Publications by authors named "Steven T Pals"

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Targeting Wnt/β-catenin signaling enhances the efficacy of anti-CD38 immunotherapy in multiple myeloma.
Heng Li, Yunguang Chen, Michaela Gregorova, Tingting Yang, Xiayi Zhang, Steven T Pals

Neoplasia· December 2025

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Presentation of CXCL12γ by heparan sulfate proteoglycans activates CXCR4 without desensitization in normal and malignant B cells.
Hildo C Lantermans, Fangxue Ma, Annemieke Kuil, Martin F M de Rooij, Nick D Bergkamp, Steven T Pals

Blood Adv· May 2025

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The dual HCK/BTK inhibitor KIN-8194 impairs growth and integrin-mediated adhesion of BTKi-resistant mantle cell lymphoma.
Hildo C Lantermans, Fangxue Ma, Annemieke Kuil, Sanne van Kesteren, Sevtap Yasinoglu, Steven T Pals

Leukemia· July 2024

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Sinonasal DLBCL: molecular profiling identifies subtypes with distinctive prognosis and targetable genetic features.
Patrick R G Eriksen, Fleur de Groot, Erik Clasen-Linde, Peter de Nully Brown, Ruben de Groen, Steven T Pals

Blood Adv· April 2024

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Expanded ILC2s in human infant intestines promote tissue growth.
Kimberly J Möller, Lucy H M Wegner, Jakob Malsy, Martin E Baumdick, Malte Borggrewe, Steven T Pals

Mucosal Immunol· August 2023

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The oncogenic human B-cell lymphoma MYD88 L265P mutation genocopies activation by phosphorylation at the Toll/interleukin-1 receptor (TIR) domain.
Marthe Minderman, Hildo Lantermans, Carmen van der Zwaan, Arie J Hoogendijk, Maartje van den Biggelaar, Steven T Pals

Blood Cancer J· August 2023

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Prevalence and prognostic value of and mutations in ocular adnexal large B-cell lymphoma: a reclassification of ocular adnexal large B-cell lymphoma.
Marina Knudsen Kirkegaard, Marthe Minderman, Lene Dissing Sjö, Steven T Pals, Patrick R G Eriksen

Br J Ophthalmol· April 2023

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Inhibition of casein kinase 2 sensitizes mantle cell lymphoma to venetoclax through MCL-1 downregulation.
Yvonne J Thus, Martin F M De Rooij, Nathalie Swier, Roderick L Beijersbergen, Jeroen E J Guikema, Steven T Pals

Haematologica· March 2023

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MALT1-dependent cleavage of CYLD promotes NF-κB signaling and growth of aggressive B-cell receptor-dependent lymphomas.
Marthe Minderman, Hildo C Lantermans, Leonie J Grüneberg, Saskia A G M Cillessen, Richard J Bende, Steven T Pals

Blood Cancer J· March 2023

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CXCR5PD-1 CD4 T cells colonize infant intestines early in life and promote B cell maturation.
Ana Jordan-Paiz, Glòria Martrus, Fenja L Steinert, Max Kaufmann, Adrian F Sagebiel, Steven T Pals

Cell Mol Immunol· February 2023

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Megalobastic anemia, infantile leukemia, and immunodeficiency caused by a novel homozygous mutation in the DHFR gene.
Taco W Kuijpers, Andrica C H de Vries, Ester M van Leeuwen, A Ton A M Ermens, Saskia de Pont, Steven T Pals

Blood Adv· November 2022

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Discriminating between Waldenström macroglobulinemia and marginal zone lymphoma using logistic LASSO regression.
Karima Amaador, Josephine M I Vos, Steven T Pals, Willem Kraan, Johan A Dobber

Leuk Lymphoma· May 2022

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A loss-of-adhesion CRISPR-Cas9 screening platform to identify cell adhesion-regulatory proteins and signaling pathways.
Martin F M de Rooij, Yvonne J Thus, Nathalie Swier, Roderick L Beijersbergen, Steven T Pals

Nat Commun· April 2022

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Combining Ixazomib With Subcutaneous Rituximab and Dexamethasone in Relapsed or Refractory Waldenström's Macroglobulinemia: Final Analysis of the Phase I/II HOVON124/ECWM-R2 Study.
Marie José Kersten, Karima Amaador, Monique C Minnema, Josephine M I Vos, Kazem Nasserinejad, Steven T Pals

J Clin Oncol· January 2022

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Frequent mutated B2M, EZH2, IRF8, and TNFRSF14 in primary bone diffuse large B-cell lymphoma reflect a GCB phenotype.
Ruben A L de Groen, Ronald van Eijk, Stefan Böhringer, Tom van Wezel, Richard Raghoo, Steven T Pals

Blood Adv· October 2021

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Immune evasion in primary testicular and central nervous system lymphomas: HLA loss rather than 9p24.1/PD-L1/PD-L2 alterations.
Marthe Minderman, Avital Amir, Willem Kraan, Esther J M Schilder-Tol, Monique E C M Oud, Steven T Pals

Blood· September 2021

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Syndecan-1 and stromal heparan sulfate proteoglycans: key moderators of plasma cell biology and myeloma pathogenesis.
Zemin Ren, Marcel Spaargaren, Steven T Pals

Blood· April 2021

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Identification of the SRC-family tyrosine kinase HCK as a therapeutic target in mantle cell lymphoma.
Hildo C Lantermans, Marthe Minderman, Annemieke Kuil, Marie-José Kersten, Steven T Pals

Leukemia· March 2021

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Correction to: The CXCL12gamma chemokine immobilized by heparan sulfate on stromal niche cells controls adhesion and mediates drug resistance in multiple myeloma.
Zemin Ren, Hildo Lantermans, Annemieke Kuil, Willem Kraan, Fernando Arenzana-Seisdedos, Steven T Pals

J Hematol Oncol· February 2021

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Spectrum of histiocytic neoplasms associated with diverse haematological malignancies bearing the same oncogenic mutation.
Paul G Kemps, Konnie M Hebeda, Steven T Pals, Robert M Verdijk, King H Lam

J Pathol Clin Res· January 2021

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A Bispecific Antibody Antagonizes Prosurvival CD40 Signaling and Promotes Vγ9Vδ2 T cell-Mediated Antitumor Responses in Human B-cell Malignancies.
Iris de Weerdt, Roeland Lameris, George L Scheffer, Jana Vree, Renate de Boer, Steven T Pals

Cancer Immunol Res· January 2021

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The CXCL12gamma chemokine immobilized by heparan sulfate on stromal niche cells controls adhesion and mediates drug resistance in multiple myeloma.
Zemin Ren, Hildo Lantermans, Annemieke Kuil, Willem Kraan, Fernando Arenzana-Seisdedos, Steven T Pals

J Hematol Oncol· January 2021

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Hepatocyte growth factor/MET and CD44 in colorectal cancer: partners in tumorigenesis and therapy resistance.
Sander P J Joosten, Marcel Spaargaren, Hans Clevers, Steven T Pals

Biochim Biophys Acta Rev Cancer· December 2020

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AKT signaling restrains tumor suppressive functions of FOXO transcription factors and GSK3 kinase in multiple myeloma.
Timon A Bloedjes, Guus de Wilde, Chiel Maas, Eric Eldering, Richard J Bende, Steven T Pals

Blood Adv· September 2020

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Towards genomic-based prognostication and precision therapy for diffuse large B-cell lymphoma.
Marthe Minderman, Steven T Pals

Haematologica· September 2020

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