Publications by authors named "Steven Y Cheng"

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A splicing variant in EFCAB7 hinders ciliary transport and disrupts cardiac development.
Xin Yang, Qiuye Wang, Tianyuan Li, Yan Zhou, Jimiao Gao, Steven Y Cheng

J Biol Chem· March 2025

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Lysozyme 1 Inflamed CCR2 Macrophages Promote Obesity-Induced Cardiac Dysfunction.
Lai Zhang, Huian Han, Andi Xu, Adwait Sathe, Siying Fu, Steven Yan Cheng

Circ Res· August 2024

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Blocking smoothened cholesterylation: A strategy for overcoming drug resistance in cancer.
Steven Y Cheng, Ying E Zhang

Cell Chem Biol· July 2024

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Increasing Sufu gene dosage reveals its unorthodox role in promoting polydactyly and medulloblastoma tumorigenesis.
Boang Han, Yu Wang, Shen Yue, Yun-Hao Zhang, Lun Kuang, Steven Y Cheng

JCI Insight· February 2024

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Hedgehog signal activates AMPK via Smoothened to promote autophagy and lipid degradation in hepatocytes.
Yixing Yao, Tianyuan Li, Tingting Yu, Xin Yang, Yue Wang, Steven Y Cheng

Biochem Cell Biol· August 2023

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Peptidomic changes in human serous colorectal cancer patients.
Jianghao Xu, Xingling Li, Wenlong Chen, Steven Yan Cheng, Jie Cheng

J Gastrointest Oncol· April 2023

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AMPK attenuates SHH subgroup medulloblastoma growth and metastasis by inhibiting NF-κB activation.
Jing Cai, Yue Wang, Xinfa Wang, Zihe Ai, Tianyuan Li, Steven Y Cheng

Cell Biosci· January 2023

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Editorial: Hedgehog signaling pathway in development and cancer.
Steven Y Cheng, Matthias Lauth, Aimin Liu

Front Cell Dev Biol· August 2022

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Macroautophagy supports Sonic Hedgehog signaling by promoting Patched1 degradation.
Xin Yang, Nan Jin, Yu Wang, Yixing Yao, Yue Wang, Steven Y Cheng

Biochim Biophys Acta Mol Cell Res· November 2021

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Sufu negatively regulates both initiations of centrosome duplication and DNA replication.
Tenghan Zhuang, Boyan Zhang, Yihong Song, Fan Huang, Wangfei Chi, Steven Y Cheng

Proc Natl Acad Sci U S A· July 2021

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SPOP-PTEN-SUFU axis promotes progression of clear cell renal cell carcinoma via activating SHH and WNT pathway.
Bo'ang Han, Zhen Sun, Tingting Yu, Yu Wang, Lun Kuang, Steven Y Cheng

Cell Death Discov· May 2021

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Identification of a potent antagonist of smoothened in hedgehog signaling.
Junwan Fan, Haowen Li, Lun Kuang, Zichen Zhao, Wenyan He, Steven Y Cheng

Cell Biosci· March 2021

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Deletion at an 1q24 locus reveals a critical role of long noncoding RNA DNM3OS in skeletal development.
Ting-Ting Yu, Qiu-Fan Xu, Si-Yang Li, Hui-Jie Huang, Sarah Dugan, Steven Y Cheng

Cell Biosci· March 2021

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Identification of four novel prognosis biomarkers and potential therapeutic drugs for human colorectal cancer by bioinformatics analysis.
Zhen Sun, Chen Liu, Steven Y Cheng

J Biomed Res· October 2020

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Protein phosphatase 4 promotes Hedgehog signaling through dephosphorylation of Suppressor of fused.
Hengqing Liao, Jing Cai, Chen Liu, Longyan Shen, Xiaohong Pu, Steven Y Cheng

Cell Death Dis· August 2020

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Tibetan Medicated Bathing Therapy for Patients With Post-stroke Limb Spasticity: A Randomized Controlled Clinical Trial.
Meng Wang, Shouguo Liu, Zhihang Peng, Yi Zhu, Xiaodong Feng, Steven Y Cheng

J Am Med Dir Assoc· March 2020

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Dual Regulatory Functions of SUFU and Targetome of GLI2 in SHH Subgroup Medulloblastoma.
Wen-Chi Yin, Thevagi Satkunendran, Rong Mo, Sorana Morrissy, Xiaoyun Zhang, Steven Y Cheng

Dev Cell· January 2020

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Dual Regulatory Functions of SUFU and Targetome of GLI2 in SHH Subgroup Medulloblastoma.
Wen-Chi Yin, Thevagi Satkunendran, Rong Mo, Sorana Morrissy, Xiaoyun Zhang, Steven Y Cheng

Dev Cell· January 2019

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Extra-mitochondrial prosurvival BCL-2 proteins regulate gene transcription by inhibiting the SUFU tumour suppressor.
Xiaofeng Wu, Li-Shu Zhang, Jason Toombs, Yi-Chun Kuo, John Tyler Piazza, Steven Y Cheng

Nat Cell Biol· October 2017

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DeSUMOylation of Gli1 by SENP1 Attenuates Sonic Hedgehog Signaling.
Huaize Liu, Sen Yan, Jie Ding, Ting-Ting Yu, Steven Y Cheng

Mol Cell Biol· September 2017

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DGKδ triggers endoplasmic reticulum release of IFT88-containing vesicles destined for the assembly of primary cilia.
Jie Ding, Lei Shao, Yixing Yao, Xin Tong, Huaize Liu, Steven Y Cheng

Sci Rep· July 2017

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Suppressor of Fused Chaperones Gli Proteins To Generate Transcriptional Responses to Sonic Hedgehog Signaling.
Ziyu Zhang, Longyan Shen, Kelvin Law, Zengdi Zhang, Xiaotong Liu, Steven Y Cheng

Mol Cell Biol· February 2017

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DAZ-interacting Protein 1 (Dzip1) Phosphorylation by Polo-like Kinase 1 (Plk1) Regulates the Centriolar Satellite Localization of the BBSome Protein during the Cell Cycle.
Boyan Zhang, Gang Wang, Xiaowei Xu, Sisi Yang, Tenghan Zhuang, Steven Y Cheng

J Biol Chem· January 2017

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Set7 mediated Gli3 methylation plays a positive role in the activation of Sonic Hedgehog pathway in mammals.
Lin Fu, Hailong Wu, Steven Y Cheng, Daming Gao, Lei Zhang

Elife· May 2016

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Up-regulation of the Hippo pathway effector TAZ renders lung adenocarcinoma cells harboring EGFR-T790M mutation resistant to gefitinib.
Wei Xu, Yunyan Wei, Shuangshuang Wu, Yun Wang, Zhen Wang, Steven Y Cheng

Cell Biosci· May 2015

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