Publications by authors named "Stuart A Cain"

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ADAMTS6 cleaves the large latent TGFβ complex and increases the mechanotension of cells to activate TGFβ.
Stuart A Cain, Steven Woods, Mukti Singh, Susan J Kimber, Clair Baldock

Matrix Biol· December 2022

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SIRT1 activity orchestrates ECM expression during hESC-chondrogenic differentiation.
Christopher A Smith, Paul A Humphreys, Nicola Bates, Mark A Naven, Stuart A Cain

FASEB J· May 2022

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Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development.
Timothy J Mead, Daniel R Martin, Lauren W Wang, Stuart A Cain, Cagri Gulec

Elife· May 2022

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Latent TGFβ complexes are transglutaminase cross-linked to fibrillin to facilitate TGFβ activation.
Michael P Lockhart-Cairns, Stuart A Cain, Rana Dajani, Ruth Steer, Jennifer Thomson

Matrix Biol· March 2022

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Delineation of a new fibrillin-2-opathy with evidence for a role of in the pathogenesis of carpal tunnel syndrome.
Silke Peeters, Arne Decramer, Stuart Alan Cain, Peter Houpt, Frederik Verstreken

J Med Genet· November 2021

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Autosomal Recessive Cutis Laxa 1C Mutations Disrupt the Structure and Interactions of Latent TGFβ Binding Protein-4.
Yasmene F Alanazi, Michael P Lockhart-Cairns, Stuart A Cain, Thomas A Jowitt, Anthony S Weiss

Front Genet· September 2021

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Regulation of TGFβ Signalling by TRPV4 in Chondrocytes.
Steven Woods, Paul A Humphreys, Nicola Bates, Sophie Alice Richardson, Shweta Yogesh Kuba, Stuart A Cain

Cells· March 2021

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Tropoelastin and Elastin Assembly.
Jazmin Ozsvar, Chengeng Yang, Stuart A Cain, Clair Baldock, Anna Tarakanova

Front Bioeng Biotechnol· February 2021

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Optogenetic Control of the BMP Signaling Pathway.
Paul A Humphreys, Steven Woods, Christopher A Smith, Nicola Bates, Stuart A Cain

ACS Synth Biol· November 2020

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Molecular Cloning, Lentiviral Transduction, and Expression of Recombinant ADAMTSL2 and ADAMTSL4.
Mukti Singh, Stuart A Cain, Clair Baldock

Methods Mol Biol· April 2020

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The role of fibrillin and microfibril binding proteins in elastin and elastic fibre assembly.
Alan R F Godwin, Mukti Singh, Michael P Lockhart-Cairns, Yasmene F Alanazi, Stuart A Cain

Matrix Biol· November 2019

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Fibrillin microfibrils and elastic fibre proteins: Functional interactions and extracellular regulation of growth factors.
Jennifer Thomson, Mukti Singh, Alexander Eckersley, Stuart A Cain, Michael J Sherratt

Semin Cell Dev Biol· May 2019

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Internal cleavage and synergy with twisted gastrulation enhance BMP inhibition by BMPER.
Michael P Lockhart-Cairns, Karen Tzia Wei Lim, Alexandra Zuk, Alan R F Godwin, Stuart A Cain

Matrix Biol· April 2019

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Effect of Topography and Physical Stimulus on hMSC Phenotype Using a 3D In Vitro Model.
Deepak Kumar, Stuart A Cain, Lucy A Bosworth

Nanomaterials (Basel)· April 2019

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ADAMTS10-mediated tissue disruption in Weill-Marchesani syndrome.
Ewa J Mularczyk, Mukti Singh, Alan R F Godwin, Francessco Galli, Neil Humphreys, Stuart A Cain

Hum Mol Genet· November 2018

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Extracellular Matrix Molecule-Based Capture of Mesenchymal Stromal Cells Under Flow.
Teresa Massam-Wu, Stuart A Cain, Cay M Kielty

Methods Mol Biol· August 2018

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Generation of Human Mesenchymal Stem Cell 3D Spheroids Using Low-binding Plates.
Elena Redondo-Castro, Catriona J Cunningham, Jonjo Miller, Stuart A Cain, Stuart M Allan

Bio Protoc· August 2018

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Recombinant Extracellular Matrix Protein Fragments Support Human Embryonic Stem Cell Chondrogenesis.
Aixin Cheng, Stuart A Cain, Pinyuan Tian, Andrew K Baldwin, Paweena Uppanan

Tissue Eng Part A· June 2018

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ADAMTS-10 and -6 differentially regulate cell-cell junctions and focal adhesions.
Stuart A Cain, Ewa J Mularczyk, Mukti Singh, Teresa Massam-Wu, Cay M Kielty

Sci Rep· October 2016

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A high-content platform to characterise human induced pluripotent stem cell lines.
Andreas Leha, Nathalie Moens, Ruta Meleckyte, Oliver J Culley, Mia K Gervasio, Stuart A Cain

Methods· March 2016

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Leri's pleonosteosis, a congenital rheumatic disease, results from microduplication at 8q22.1 encompassing GDF6 and SDC2 and provides insight into systemic sclerosis pathogenesis.
Siddharth Banka, Stuart A Cain, Sabrya Carim, Sarah B Daly, Jill E Urquhart

Ann Rheum Dis· June 2015

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Comparative quantification of the surfaceome of human multipotent mesenchymal progenitor cells.
Rebecca J Holley, Guangping Tai, Andrew J K Williamson, Samuel Taylor, Stuart A Cain

Stem Cell Reports· March 2015

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Epithelial-mesenchymal status influences how cells deposit fibrillin microfibrils.
Andrew K Baldwin, Stuart A Cain, Rachel Lennon, Alan Godwin, Catherine L R Merry

J Cell Sci· January 2014

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Elastic fibres in health and disease.
Andrew K Baldwin, Andreja Simpson, Ruth Steer, Stuart A Cain, Cay M Kielty

Expert Rev Mol Med· August 2013

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Fibrillin-1 mutations causing Weill-Marchesani syndrome and acromicric and geleophysic dysplasias disrupt heparan sulfate interactions.
Stuart A Cain, Amanda McGovern, Andrew K Baldwin, Clair Baldock, Cay M Kielty

PLoS One· May 2013

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