Publications by authors named "Stuart A Morgan"

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Glucocorticoid excess alters metabolic rate and substrate utilisation via 11β-HSD1.
Samuel R Heaselgrave, Silke Heising, Stuart A Morgan, David M Carthwright, Michael Sagmeister

J Endocrinol· November 2024

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11β-HSD1 contributes to age-related metabolic decline in male mice.
Stuart A Morgan, Laura L Gathercole, Zaki K Hassan-Smith, Jeremy Tomlinson, Paul M Stewart

J Endocrinol· December 2022

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Regulation of 11β-HSD1 by GH/IGF-1 in key metabolic tissues may contribute to metabolic disease in GH deficient patients.
Stuart A Morgan, Darlene E Berryman, Edward O List, Gareth G Lavery, Paul M Stewart

Growth Horm IGF Res· February 2022

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25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 exert distinct effects on human skeletal muscle function and gene expression.
Zaki K Hassan-Smith, Carl Jenkinson, David J Smith, Ivan Hernandez, Stuart A Morgan

PLoS One· August 2017

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The CRH-Transgenic Cushingoid Mouse Is a Model of Glucocorticoid-Induced Osteoporosis.
Jasmine Williams-Dautovich, Keertika Yogendirarajah, Ariana Dela Cruz, Rucha Patel, Ricky Tsai, Stuart A Morgan

JBMR Plus· August 2017

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11β-HSD1 Modulates the Set Point of Brown Adipose Tissue Response to Glucocorticoids in Male Mice.
Craig L Doig, Rachel S Fletcher, Stuart A Morgan, Emma L McCabe, Dean P Larner

Endocrinology· June 2017

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11β-Hydroxysteroid dehydrogenase type 1 within muscle protects against the adverse effects of local inflammation.
Rowan S Hardy, Craig L Doig, Zahrah Hussain, Mary O'Leary, Stuart A Morgan

J Pathol· December 2016

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Male 11β-HSD1 Knockout Mice Fed Trans-Fats and Fructose Are Not Protected From Metabolic Syndrome or Nonalcoholic Fatty Liver Disease.
Dean P Larner, Stuart A Morgan, Laura L Gathercole, Craig L Doig, Phil Guest

Endocrinology· September 2016

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MECHANISMS IN ENDOCRINOLOGY: Tissue-specific activation of cortisol in Cushing's syndrome.
Stuart A Morgan, Zaki K Hassan-Smith, Gareth G Lavery

Eur J Endocrinol· August 2016

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Glucocorticoids and 11β-HSD1 are major regulators of intramyocellular protein metabolism.
Stuart A Morgan, Zaki K Hassan-Smith, Craig L Doig, Mark Sherlock, Paul M Stewart

J Endocrinol· June 2016

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Gender-Specific Differences in Skeletal Muscle 11β-HSD1 Expression Across Healthy Aging.
Zaki K Hassan-Smith, Stuart A Morgan, Mark Sherlock, Beverly Hughes, Angela E Taylor

J Clin Endocrinol Metab· July 2015

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11β-Hydroxysteroid dehydrogenase-1 is involved in bile acid homeostasis by modulating fatty acid transport protein-5 in the liver of mice.
Carlos A Penno, Stuart A Morgan, Adam J Rose, Stephan Herzig, Gareth G Lavery

Mol Metab· August 2014

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11β-HSD1 is the major regulator of the tissue-specific effects of circulating glucocorticoid excess.
Stuart A Morgan, Emma L McCabe, Laura L Gathercole, Zaki K Hassan-Smith, Dean P Larner

Proc Natl Acad Sci U S A· June 2014

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Hormonal regulation of lipogenesis.
Laura L Gathercole, Stuart A Morgan, Jeremy W Tomlinson

Vitam Horm· December 2013

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Loss of 5α-reductase type 1 accelerates the development of hepatic steatosis but protects against hepatocellular carcinoma in male mice.
Joanna K Dowman, Laurence J Hopkins, Gary M Reynolds, Matthew J Armstrong, Maryam Nasiri, Stuart A Morgan

Endocrinology· December 2013

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Impaired oxidoreduction by 11β-hydroxysteroid dehydrogenase 1 results in the accumulation of 7-oxolithocholic acid.
Carlos A Penno, Stuart A Morgan, Anna Vuorinen, Daniela Schuster, Gareth G Lavery

J Lipid Res· October 2013

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11β-Hydroxysteroid dehydrogenase 1: translational and therapeutic aspects.
Laura L Gathercole, Gareth G Lavery, Stuart A Morgan, Mark S Cooper, Alexandra J Sinclair

Endocr Rev· August 2013

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Regulation of lipid metabolism by glucocorticoids and 11β-HSD1 in skeletal muscle.
Stuart A Morgan, Laura L Gathercole, Claire Simonet, Zaki K Hassan-Smith, Iwona Bujalska

Endocrinology· July 2013

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11β-Hydroxysteroid dehydrogenase blockade prevents age-induced skin structure and function defects.
Ana Tiganescu, Abd A Tahrani, Stuart A Morgan, Marcela Otranto, Alexis Desmoulière

J Clin Invest· July 2013

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Inflammatory regulation of glucocorticoid metabolism in mesenchymal stromal cells.
Mohammad M Ahasan, Rowan Hardy, Christopher Jones, Kirren Kaur, Dominika Nanus, Stuart A Morgan

Arthritis Rheum· July 2012

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Lack of significant metabolic abnormalities in mice with liver-specific disruption of 11β-hydroxysteroid dehydrogenase type 1.
Gareth G Lavery, Agnieszka E Zielinska, Laura L Gathercole, Beverly Hughes, Nina Semjonous, Stuart A Morgan

Endocrinology· July 2012

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Regulation of lipogenesis by glucocorticoids and insulin in human adipose tissue.
Laura L Gathercole, Stuart A Morgan, Iwona J Bujalska, David Hauton, Paul M Stewart

PLoS One· February 2012

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11beta-hydroxysteroid dehydrogenase type 1 inhibitors for the treatment of type 2 diabetes.
Stuart A Morgan, Jeremy W Tomlinson

Expert Opin Investig Drugs· September 2010

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11beta-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid-induced insulin resistance in skeletal muscle.
Stuart A Morgan, Mark Sherlock, Laura L Gathercole, Gareth G Lavery, Carol Lenaghan

Diabetes· November 2009

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