Publications by authors named "Stuart A Sievers"

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In vivo CAR T cell generation to treat cancer and autoimmune disease.
Theresa L Hunter, Yanjie Bao, Yan Zhang, Daiki Matsuda, Romina Riener, Stuart A Sievers

Science· June 2025

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Activation of CAR and non-CAR T cells within the tumor microenvironment following CAR T cell therapy.
Pei-Hsuan Chen, Mikel Lipschitz, Jason L Weirather, Caron Jacobson, Philippe Armand, Stuart A Sievers

JCI Insight· June 2020

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Crystal structures of amyloidogenic segments of human transthyretin.
Lorena Saelices, Stuart A Sievers, Michael R Sawaya, David S Eisenberg

Protein Sci· July 2018

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Function of Novel Anti-CD19 Chimeric Antigen Receptors with Human Variable Regions Is Affected by Hinge and Transmembrane Domains.
Leah Alabanza, Melissa Pegues, Claudia Geldres, Victoria Shi, Jed J W Wiltzius, Stuart A Sievers

Mol Ther· November 2017

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Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller.
Natalia T Freund, Haoqing Wang, Louise Scharf, Lilian Nogueira, Joshua A Horwitz, Stuart A Sievers

Sci Transl Med· January 2017

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Structural basis for germline antibody recognition of HIV-1 immunogens.
Louise Scharf, Anthony P West, Stuart A Sievers, Courtney Chen, Siduo Jiang

Elife· March 2016

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A New Glycan-Dependent CD4-Binding Site Neutralizing Antibody Exerts Pressure on HIV-1 In Vivo.
Natalia T Freund, Joshua A Horwitz, Lilian Nogueira, Stuart A Sievers, Louise Scharf

PLoS Pathog· October 2015

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Antibody engineering for increased potency, breadth and half-life.
Stuart A Sievers, Louise Scharf, Anthony P West, Pamela J Bjorkman

Curr Opin HIV AIDS· May 2015

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Structure-based design of functional amyloid materials.
Dan Li, Eric M Jones, Michael R Sawaya, Hiroyasu Furukawa, Fang Luo, Stuart A Sievers

J Am Chem Soc· December 2014

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Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS.
Magdalena I Ivanova, Stuart A Sievers, Elizabeth L Guenther, Lisa M Johnson, Duane D Winkler

Proc Natl Acad Sci U S A· January 2014

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Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation.
Stuart A Sievers, John Karanicolas, Howard W Chang, Anni Zhao, Lin Jiang

Nature· June 2011

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Towards a pharmacophore for amyloid.
Meytal Landau, Michael R Sawaya, Kym F Faull, Arthur Laganowsky, Lin Jiang, Stuart A Sievers

PLoS Biol· June 2011

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Molecular basis for insulin fibril assembly.
Magdalena I Ivanova, Stuart A Sievers, Michael R Sawaya, Joseph S Wall, David Eisenberg

Proc Natl Acad Sci U S A· November 2009

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Atomic structures of IAPP (amylin) fusions suggest a mechanism for fibrillation and the role of insulin in the process.
Jed J W Wiltzius, Stuart A Sievers, Michael R Sawaya, David Eisenberg

Protein Sci· July 2009

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Atomic structure of the cross-beta spine of islet amyloid polypeptide (amylin).
Jed J W Wiltzius, Stuart A Sievers, Michael R Sawaya, Duilio Cascio, Dmitriy Popov

Protein Sci· September 2008

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Draft crystal structure of the vault shell at 9-A resolution.
Daniel H Anderson, Valerie A Kickhoefer, Stuart A Sievers, Leonard H Rome, David Eisenberg

PLoS Biol· November 2007

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Atomic structures of amyloid cross-beta spines reveal varied steric zippers.
Michael R Sawaya, Shilpa Sambashivan, Rebecca Nelson, Magdalena I Ivanova, Stuart A Sievers

Nature· May 2007

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The TCL1 oncoprotein binds the RNase PH domains of the PNPase exoribonuclease without affecting its RNA degrading activity.
Samuel W French, David W Dawson, Hsiao-Wen Chen, Robert N Rainey, Stuart A Sievers

Cancer Lett· April 2007

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Identification and biochemical characterization of serine hydroxymethyl transferase in the hydrogenosome of Trichomonas vaginalis.
Mandira Mukherjee, Stuart A Sievers, Mark T Brown, Patricia J Johnson

Eukaryot Cell· December 2006

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The 3D profile method for identifying fibril-forming segments of proteins.
Michael J Thompson, Stuart A Sievers, John Karanicolas, Magdalena I Ivanova, David Baker

Proc Natl Acad Sci U S A· March 2006

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