Publications by authors named "Stuart Ballantine"

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Integration of lead optimization with crystallography for a membrane-bound ion channel target: discovery of a new class of AMPA receptor positive allosteric modulators.
Simon E Ward, Mark Harries, Laura Aldegheri, Nigel E Austin, Stuart Ballantine

J Med Chem· January 2011

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Pyrazolopyridines as potent PDE4B inhibitors: 5-heterocycle SAR.
Charlotte J Mitchell, Stuart P Ballantine, Diane M Coe, Caroline M Cook, Christopher J Delves

Bioorg Med Chem Lett· October 2010

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Discovery of N-[(2S)-5-(6-fluoro-3-pyridinyl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide, a novel clinical AMPA receptor positive modulator.
Simon E Ward, Mark Harries, Laura Aldegheri, Daniele Andreotti, Stuart Ballantine

J Med Chem· August 2010

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Quinolines as a novel structural class of potent and selective PDE4 inhibitors. Optimisation for inhaled administration.
Michael D Woodrow, Stuart P Ballantine, Michael D Barker, Beth J Clarke, John Dawson

Bioorg Med Chem Lett· September 2009

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Identification of PDE4B Over 4D subtype-selective inhibitors revealing an unprecedented binding mode.
Michael Kranz, Michael Wall, Brian Evans, Afjal Miah, Stuart Ballantine

Bioorg Med Chem· July 2009

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Pyrazolopyridines as a novel structural class of potent and selective PDE4 inhibitors.
J Nicole Hamblin, Tony D R Angell, Stuart P Ballantine, Caroline M Cook, Anthony W J Cooper

Bioorg Med Chem Lett· July 2008

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