Publications by authors named "Subin George"

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An early-stage 3D fibroblast-featured tumor model mimics the gene expression of the naïve tumor microenvironment, including genes involved in cancer progression and drug resistance.
Francesca Costabile, Subin George, Andrea Facciabene, Gilberto Filaci, Maddalena Mastrogiacomo

Front Oncol· November 2025

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Leukemia mutated proteins PHF6 and PHIP form a chromatin complex that represses acute myeloid leukemia stemness.
Aishwarya S Pawar, Patrick Somers, Aleena Alex, Jason Grana, Victoria K Feist, Subin S George

Genes Dev· October 2025

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Development, optimization, and prototyping of a simplified sit-stand mechanism for lower limb impairments.
Subin P George, Mervin Joe Thomas, Meby Mathew, Naveen Gangadharan, Arun K Varghese

Med Biol Eng Comput· October 2025

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Dynamics of Ribosomal RNA Transcription and Abundance in Normal and Leukemic Hematopoiesis.
Eleanor I Sams, Victoria K Feist, Erin M Gray, Subin S George, Charles Antony

bioRxiv· August 2025

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Leukemia-mutated proteins PHF6 and PHIP form a chromatin complex that represses acute myeloid leukemia stemness.
Aishwarya S Pawar, Patrick Somers, Aleena Alex, Subin S George, Charles Antony

bioRxiv· December 2024

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PHF6 suppresses self-renewal of leukemic stem cells in AML.
Sapana S Jalnapurkar, Aishwarya S Pawar, Subin S George, Charles Antony, Patrick Somers

Leukemia· September 2024

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Modified C-type natriuretic peptide normalizes tumor vasculature, reinvigorates antitumor immunity, and improves solid tumor therapies.
Zhen Lu, Ioannis Verginadis, Motofumi Kumazoe, Gerardo M Castillo, Yao Yao, George McClung, Subin S George

Sci Transl Med· August 2024

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PARP11 inhibition inactivates tumor-infiltrating regulatory T cells and improves the efficacy of immunotherapies.
Raghavendra Basavaraja, Hongru Zhang, Ágnes Holczbauer, Zhen Lu, Enrico Radaelli, Subin S George

Cell Rep Med· July 2024

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ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes.
Zhen Lu, Noreen McBrearty, Jinyun Chen, Vivek S Tomar, Hongru Zhang, Subin S George

Cell Metab· May 2024

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PHF6 suppresses self-renewal of leukemic stem cells in AML.
Sapana S Jalnapurkar, Aishwarya Pawar, Subin S George, Charles Antony, Jason Grana

bioRxiv· January 2024

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Parkin Deficiency Suppresses Antigen Presentation to Promote Tumor Immune Evasion and Immunotherapy Resistance.
Renzo Perales-Linares, Nektaria Maria Leli, Hesham Mohei, Silvia Beghi, Osvaldo D Rivera, Subin S George

Cancer Res· November 2023

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Development, calibration and validation of a comprehensive customizable lumbar spine FE model for simulating fusion constructs.
Subin P George, K Venkatesh, G Saravana Kumar

Med Eng Phys· August 2023

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Construction and validation of customized genomes for human and mouse ribosomal DNA mapping.
Subin S George, Maxim Pimkin, Vikram R Paralkar

J Biol Chem· June 2023

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Induction of the activating transcription factor-4 in the intratumoral CD8+ T cells sustains their viability and anti-tumor activities.
Zhen Lu, Eun-Ah Bae, Ioannis I Verginadis, Hongru Zhang, Christina Cho, Subin S George

Cancer Immunol Immunother· April 2023

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Modulation of the gut microbiota engages antigen cross-presentation to enhance antitumor effects of CAR T cell immunotherapy.
Mireia Uribe-Herranz, Silvia Beghi, Marco Ruella, Kalpana Parvathaneni, Silvano Salaris, Subin S George

Mol Ther· March 2023

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Tumor factors stimulate lysosomal degradation of tumor antigens and undermine their cross-presentation in lung cancer.
Zhen Lu, Jinyun Chen, Pengfei Yu, Matthew J Atherton, Jun Gui, Subin S George

Nat Commun· November 2022

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Control of ribosomal RNA synthesis by hematopoietic transcription factors.
Charles Antony, Subin S George, Justin Blum, Patrick Somers, Chelsea L Thorsheim

Mol Cell· October 2022

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ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes.
Zhen Lu, Noreen McBrearty, Jinyun Chen, Vivek S Tomar, Hongru Zhang, Subin S George

Cell Metab· September 2022

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Targeting PARP11 to avert immunosuppression and improve CAR T therapy in solid tumors.
Hongru Zhang, Pengfei Yu, Vivek S Tomar, Xiangjie Chen, Matthew J Atherton, Subin S George

Nat Cancer· July 2022

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A glass-based, continuously zonated and vascularized human liver acinus microphysiological system (vLAMPS) designed for experimental modeling of diseases and ADME/TOX.
Xiang Li, Subin M George, Lawrence Vernetti, Albert H Gough, D Lansing Taylor

Lab Chip· August 2018

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Control of oxygen tension recapitulates zone-specific functions in human liver microphysiology systems.
Felipe T Lee-Montiel, Subin M George, Albert H Gough, Anup D Sharma, Juanfang Wu

Exp Biol Med (Maywood)· October 2017

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Optimization of custom cementless stem using finite element analysis and elastic modulus distribution for reducing stress-shielding effect.
Gurunathan Saravana Kumar, Subin Philip George

Proc Inst Mech Eng H· February 2017

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Digital microfluidic three-dimensional cell culture and chemical screening platform using alginate hydrogels.
Subin M George, Hyejin Moon

Biomicrofluidics· March 2015

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