Publications by authors named "Sudarshan Rajagopal"

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The emerging role of hyperpolarized Xe MRI in pulmonary hypertension.
Fawaz Alenezi, Anna Costelle, Seth Lee, Bastiaan Driehuys, Sudarshan Rajagopal

Expert Rev Respir Med· December 2025

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Right Ventricular Dysfunction at echocardiography to Predict Mortality in Acute Pulmonary Embolism: an IPDMA.
Ludovica Anna Cimini, Piotr Pruszczyk, David Jiménez, Anthony Weekes, Marco Zuin, Sudarshan Rajagopal

J Thromb Haemost· December 2025

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Pericardial effusions and sotatercept therapy in pulmonary arterial hypertension: a multicentre, real-world experience.
Sandeep Sahay, Nelson Villasmil Hernandez, Yassmin Al Aaraj, Rahul G Argula, Roberto J Bernardo, Sudarshan Rajagopal

Eur Respir J· October 2025

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Biased Agonists of the Type 1 Angiotensin II Receptor Promote Distinct Subcellular β-Arrestin Conformations.
Anand Chundi, Uyen Pham, Srikrishna Darbha, Sudarshan Rajagopal

Biochemistry· October 2025

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CXCR1 and CXCR2 display receptor bias for shared chemokine agonists.
Chanpreet Jassal, Joseph Strawn, Krishna Rajarathnam, Sudarshan Rajagopal

bioRxiv· October 2025

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Mechanisms of Location Bias in G Protein-Coupled Receptors.
Uyen Pham, Anand Chundi, Sudarshan Rajagopal

Handb Exp Pharmacol· September 2025

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Clinical validation of a machine-learned, point-of-care system to IDENTIFY pulmonary hypertension.
Dalton McLean, John Rommel, John A Steuter, William S Carroll, Mark Rabbat, Sudarshan Rajagopal

ERJ Open Res· September 2025

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β-arrestin recruitment facilitates a direct association with G proteins.
Claudia Y Lee, Jeffrey S Smith, Taylor Kohlmann, Emily M Meara, Uyen Pham, Sudarshan Rajagopal

bioRxiv· July 2025

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β-Arrestin Condensates Regulate G Protein-Coupled Receptor Function.
Preston J Anderson, Peng Xiao, Yani Zhong, Adam Kaakati, Juliana Alfonso-DeSouza, Sudarshan Rajagopal

bioRxiv· April 2025

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Combining hyperpolarized Xe MR imaging and spectroscopy to noninvasively estimate pulmonary vascular resistance.
Anna Costelle, Junlan Lu, Suphachart Leewiwatwong, Berend Westerhof, David Mummy, Sudarshan Rajagopal

J Appl Physiol (1985)· March 2025

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Xenon-129 magnetic resonance imaging and spectroscopy detects response to therapy in pulmonary hypertension.
Fawaz Alenezi, Anna Costelle, Prerna Sharma, Megan Barrett, Elianna A Bier, Sudarshan Rajagopal

Eur Respir J· February 2025

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Evaluation of patients with severe pulmonary hypertension and a range of comorbidities prescribed inhaled treprostinil.
Aparna C Swaminathan, Amber Meservey, Alice Parish, Cynthia L Green, Kishan Parikh, Sudarshan Rajagopal

JHLT Open· November 2024

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Emerging multimodality imaging techniques for the pulmonary circulation.
Sudarshan Rajagopal, Harm J Bogaard, Mohammed S M Elbaz, Benjamin H Freed, Martine Remy-Jardin

Eur Respir J· October 2024

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Location-biased β-arrestin conformations direct GPCR signaling.
Uyen Pham, Anand Chundi, Tomasz Maciej Stępniewski, Srikrishna Darbha, Dylan Scott Eiger, Sudarshan Rajagopal

bioRxiv· September 2024

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Phosphorylation patterns in the AT1R C-terminal tail specify distinct downstream signaling pathways.
Clarice Gareri, Conrad T Pfeiffer, Xue Jiang, Joao A Paulo, Steven P Gygi, Sudarshan Rajagopal

Sci Signal· August 2024

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G Protein-Coupled Receptors: A Century of Research and Discovery.
Samuel Liu, Preston J Anderson, Sudarshan Rajagopal, Robert J Lefkowitz, Howard A Rockman

Circ Res· June 2024

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Optimized quantitative mapping of cardiopulmonary oscillations using hyperpolarized Xe gas exchange MRI: Digital phantoms and clinical evaluation in CTEPH.
Junlan Lu, Fawaz Alenezi, Elianna Bier, Suphachart Leewiwatwong, David Mummy, Sudarshan Rajagopal

Magn Reson Med· April 2024

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GPCR kinases differentially modulate biased signaling downstream of CXCR3 depending on their subcellular localization.
Julia Gardner, Dylan Scott Eiger, Chloe Hicks, Issac Choi, Uyen Pham, Sudarshan Rajagopal

Sci Signal· February 2024

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Determining the Architecture of Inflammation in Pulmonary Arterial Hypertension.
Sudarshan Rajagopal, Yen-Rei Yu

Am J Respir Crit Care Med· January 2024

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ACKR3 Proximity Labeling Identifies Novel G protein- and β-arrestin-independent GPCR Interacting Proteins.
Chloe Hicks, Julia Gardner, Dylan Scott Eiger, Nicholas D Camarda, Uyen Pham, Sudarshan Rajagopal

bioRxiv· January 2024

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Location bias: A "Hidden Variable" in GPCR pharmacology.
Dylan Scott Eiger, Chloe Hicks, Julia Gardner, Uyen Pham, Sudarshan Rajagopal

Bioessays· November 2023

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How carvedilol does not activate β-adrenoceptors.
Robert J Lefkowitz, Howard A Rockman, Paul J Shim, Samuel Liu, Seungkirl Ahn, Sudarshan Rajagopal

Nat Commun· November 2023

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Inhaled Epoprostenol Compared With Nitric Oxide for Right Ventricular Support After Major Cardiac Surgery.
Kamrouz Ghadimi, Jhaymie L Cappiello, Mary Cooter Wright, Jerrold H Levy, Benjamin S Bryner, Sudarshan Rajagopal

Circulation· October 2023

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Quantitative assessment of ligand bias from bias plots: The bias coefficient "kappa".
Kelly Karl, Sudarshan Rajagopal, Kalina Hristova

Biochim Biophys Acta Gen Subj· October 2023

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Overcoming Confounding to Characterize the Effects of Calcium Channel Blockers.
Sudarshan Rajagopal, Paul B Rosenberg

Function (Oxf)· October 2023

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