Publications by authors named "Sudhakar Jha"

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USP10/GSK3β-mediated inhibition of PTEN drives resistance to PI3K inhibitors in breast cancer.
Nishi Kumari, Sarah Ce Wright, Christopher M Witham, Laia Monserrat, Marta Palafox, Sudhakar Jha

J Clin Invest· November 2025

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Case report of a rare variant of adult intussusception with delayed presentation: idiopathic ileocecal colic intussusception.
Rahul Jha, Sabin Kumar Ghimire, Rishika Prasad, Kaushal Samsher Thapa, Sudhakar Jha

Ann Med Surg (Lond)· August 2025

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A Prospective Observational Study on Use of Acute Physiology and Chronic Health Evaluation-II and Sequential Organ Failure Assessment Score to Predict Outcome.
Niraj Kumar Keyal, Sudhakar Jha, Shahnaj Parween, Ishfa Banu Haque, Tauqueer Ansari

J Nepal Health Res Counc· June 2025

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The TIP60-CD44 Axis Modulates Colorectal Cancer Stemness.
Asad Mohammad, Sudhakar Jha

Cells· May 2025

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E4F1 and ZNF148 are transcriptional activators of the -57A > C and wild-type promoter.
Boon Haow Chua, Nurkaiyisah Zaal Anuar, Laure Ferry, Cecilia Domrane, Anna Wittek, Sudhakar Jha

Genome Res· December 2023

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Histone-lysine N-methyltransferase EHMT2 (G9a) inhibition mitigates tumorigenicity in Myc-driven liver cancer.
Dexter Kai Hao Thng, Lissa Hooi, Clarissa Chin Min Toh, Jhin Jieh Lim, Deepa Rajagopalan, Sudhakar Jha

Mol Oncol· November 2023

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Oncoviruses: How do they hijack their host and current treatment regimes.
Kainat Ahmed, Sudhakar Jha

Biochim Biophys Acta Rev Cancer· September 2023

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Targeting RNA Exonuclease XRN1 Potentiates Efficacy of Cancer Immunotherapy.
Xue-Bin Ran, Ling-Wen Ding, Qiao-Yang Sun, Henry Yang, Jonathan W Said, Sudhakar Jha

Cancer Res· March 2023

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Epimutations and Their Effect on Chromatin Organization: Exciting Avenues for Cancer Treatment.
Asad Mohammad, Sudhakar Jha

Cancers (Basel)· December 2022

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Integrative epigenomic and high-throughput functional enhancer profiling reveals determinants of enhancer heterogeneity in gastric cancer.
Taotao Sheng, Shamaine Wei Ting Ho, Wen Fong Ooi, Chang Xu, Manjie Xing, Sudhakar Jha

Genome Med· October 2021

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GAGE mediates radio resistance in cervical cancers via the regulation of chromatin accessibility.
Dawn Sijin Nin, Caryn Wujanto, Tuan Zea Tan, Diana Lim, J Mirjam A Damen, Sudhakar Jha

Cell Rep· August 2021

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Hypertension among Young Adults with Ischemic Stroke of a Tertiary Care Centre in Nepal: A Descriptive Cross-sectional Study.
Dilli Ram Kafle, Sudhakar Jha

JNMA J Nepal Med Assoc· August 2021

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The oncogenic E3 ligase TRIP12 suppresses epithelial-mesenchymal transition (EMT) and mesenchymal traits through ZEB1/2.
Kwok Kin Lee, Deepa Rajagopalan, Shreshtha Sailesh Bhatia, Roberto Tirado-Magallanes, Wee Joo Chng, Sudhakar Jha

Cell Death Discov· May 2021

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Lysine acetyltransferase Tip60 is required for hematopoietic stem cell maintenance.
Akihiko Numata, Hui Si Kwok, Qi-Ling Zhou, Jia Li, Roberto Tirado-Magallanes, Sudhakar Jha

Blood· October 2020

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circASXL1-1 regulates BAP1 deubiquitinase activity in leukemia.
Shweta Pradip Jadhav, Nishi Kumari, Larry Ng, Pei Fang Tan, Nicole Shu Ling Yeo-Teh, Sudhakar Jha

Haematologica· July 2020

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Frequent upregulation of G9a promotes RelB-dependent proliferation and survival in multiple myeloma.
Xi Yun Zhang, Deepa Rajagopalan, Tae-Hoon Chung, Lissa Hooi, Tan Boon Toh, Sudhakar Jha

Exp Hematol Oncol· May 2020

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TFregulomeR reveals transcription factors' context-specific features and functions.
Quy Xiao Xuan Lin, Denis Thieffry, Sudhakar Jha, Touati Benoukraf

Nucleic Acids Res· January 2020

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MethMotif: an integrative cell specific database of transcription factor binding motifs coupled with DNA methylation profiles.
Quy Xiao Xuan Lin, Stephanie Sian, Omer An, Denis Thieffry, Sudhakar Jha

Nucleic Acids Res· January 2019

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TIP60 represses activation of endogenous retroviral elements.
Deepa Rajagopalan, Roberto Tirado-Magallanes, Shreshtha Sailesh Bhatia, Wen Shiun Teo, Stephanie Sian, Sudhakar Jha

Nucleic Acids Res· October 2018

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Optimizing drug combinations against multiple myeloma using a quadratic phenotypic optimization platform (QPOP).
Masturah Bte Mohd Abdul Rashid, Tan Boon Toh, Lissa Hooi, Aleidy Silva, Yanzhou Zhang, Sudhakar Jha

Sci Transl Med· August 2018

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High-Risk Human Papillomaviral Oncogenes E6 and E7 Target Key Cellular Pathways to Achieve Oncogenesis.
Nicole S L Yeo-Teh, Yoshiaki Ito, Sudhakar Jha

Int J Mol Sci· June 2018

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An epi(c)genetic war: Pathogens, cancer and human genome.
Deepa Rajagopalan, Sudhakar Jha

Biochim Biophys Acta Rev Cancer· April 2018

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Inhibition of the H3K9 methyltransferase G9A attenuates oncogenicity and activates the hypoxia signaling pathway.
Jolene Caifeng Ho, Lissa Nurrul Abdullah, Qing You Pang, Sudhakar Jha, Edward Kai-Hua Chow

PLoS One· December 2017

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Live-imaging of Breast Epithelial Cell Migration After the Transient Depletion of TIP60.
Yanzhou Zhang, Grace SuShin Chia, Cheng Yong Tham, Sudhakar Jha

J Vis Exp· December 2017

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Hypomethylation associated enhanced transcription of trefoil factor-3 mediates tamoxifen-stimulated oncogenicity of ER+ endometrial carcinoma cells.
Vijay Pandey, Min Zhang, Qing-Yun Chong, Mingliang You, Ainiah Rushdiana Raquib, Sudhakar Jha

Oncotarget· September 2017

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