Publications by authors named "Sujan Shresta"

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Structure of a SARS-CoV-2 spike S2 subunit in a pre-fusion, open conformation.
Eduardo Olmedillas, Roshan R Rajamanickam, Ruben Diaz Avalos, Fernanda Ana-Sosa-Batiz, Dawid Zyla, Sujan Shresta

Cell Rep· August 2025

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Structural stabilization of the intrinsically disordered SARS-CoV-2 N by binding to RNA sequences engineered from the viral genome fragment.
Sara Landeras-Bueno, Chitra Hariharan, Ruben Diaz Avalos, Andrew S Norris, Dalton T Snyder, Sujan Shresta

Nat Commun· July 2025

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Enhanced durability of a Zika virus self-amplifying RNA vaccine through combinatorial OX40 and 4-1BB agonism.
Hsueh-Han Lu, Rúbens Prince Dos Santos Alves, Qin Hui Li, Luke Eder, Julia Timis, Sujan Shresta

JCI Insight· May 2025

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A humanised ACE2, TMPRSS2, and FCGRT mouse model reveals the protective efficacy of anti-receptor binding domain antibodies elicited by SARS-CoV-2 hybrid immunity.
Fernanda Ana-Sosa-Batiz, Shailendra Kumar Verma, Norazizah Shafee, Robyn Miller, Chris Conner, Sujan Shresta

EBioMedicine· March 2025

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Zika but not Dengue virus infection limits NF-κB activity in human monocyte-derived dendritic cells and suppresses their ability to activate T cells.
Ying-Ting Wang, Emilie Branche, Jialei Xie, Rachel E McMillan, Fernanda Ana-Sosa-Batiz, Sujan Shresta

Nat Commun· March 2025

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Genomic surveillance of SARS-CoV-2 in Nepal.
Binod Khadka, Rajindra Napit, Kathie A Mihindukulasuriya, Smita Shrestha, Ramanuj Rauniyar, Sujan Shresta

Microbiol Resour Announc· December 2024

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Co-immunization with spike and nucleocapsid based DNA vaccines for long-term protective immunity against SARS-CoV-2 Omicron.
Paolla Beatriz Almeida Pinto, Julia Timis, Kantinan Chuensirikulchai, Qin Hui Li, Hsueh Han Lu, Sujan Shresta

NPJ Vaccines· December 2024

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Human immunodeficiency virus-1 genome from patient with fever, Nepal.
Eans Tara Tuladhar, Bimal Sharma Chalise, Binod Khadka, Mamta Tamang, Jenish Neupane, Sujan Shresta

Microbiol Resour Announc· November 2024

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Genomic sequencing and neutralizing serological profiles during acute dengue infection: A 2017 cohort study in Nepal.
Sabita Prajapati, Annie Elong Ngono, Melanie Mc Cauley, Julia Timis, Srijan Shrestha, Sujan Shresta

PLOS Glob Public Health· November 2024

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Influence of Th1 versus Th2 immune bias on viral, pathological, and immunological dynamics in SARS-CoV-2 variant-infected human ACE2 knock-in mice.
Shailendra Kumar Verma, Fernanda Ana-Sosa-Batiz, Julia Timis, Norazizah Shafee, Erin Maule, Sujan Shresta

EBioMedicine· October 2024

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Dengue virus surveillance in Nepal yields the first on-site whole genome sequences of isolates from the 2022 outbreak.
Rajindra Napit, Annie Elong Ngono, Kathie A Mihindukulasuriya, Aunji Pradhan, Binod Khadka, Sujan Shresta

BMC Genomics· October 2024

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Gemykibivirus detection in acute encephalitis patients from Nepal.
Eans Tara Tuladhar, Smita Shrestha, Susan Vernon, Lindsay Droit, Kathie A Mihindukulasuriya, Sujan Shresta

mSphere· July 2024

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Genomic sequencing and neutralizing serological profiles during acute dengue infection: A 2017 cohort study in Nepal.
Sabita Prajapati, Annie Elong Ngono, Melanie Mc Cauley, Julia Timis, Srijan Shrestha, Sujan Shresta

bioRxiv· June 2024

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Dengue Virus Surveillance in Nepal Yields the First On-Site Whole Genome Sequences of Isolates from the 2022 Outbreak.
Rajindra Napit, Annie Elong Ngono, Kathie A Mihindukulasuriya, Aunji Pradhan, Binod Khadka, Sujan Shresta

bioRxiv· June 2024

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Gemykibivirus detection in acute encephalitis patients from Nepal.
Eans Tara Tuladhar, Smita Shrestha, Susan Vernon, Lindsay Droit, Kathie A Mihindukulasuriya, Sujan Shresta

medRxiv· February 2024

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Human coronavirus OC43-elicited CD4 T cells protect against SARS-CoV-2 in HLA transgenic mice.
Rúbens Prince Dos Santos Alves, Julia Timis, Robyn Miller, Kristen Valentine, Paolla Beatriz Almeida Pinto, Sujan Shresta

Nat Commun· January 2024

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Structure of a SARS-CoV-2 spike S2 subunit in a pre-fusion, open conformation.
Eduardo Olmedillas, Roshan R Rajamanickam, Ruben Diaz Avalos, Fernanda A Sosa, Michelle A Zandonatti, Sujan Shresta

bioRxiv· December 2023

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Potent Omicron-neutralizing antibodies isolated from a patient vaccinated 6 months before Omicron emergence.
Kathryn M Hastie, Xiaoying Yu, Fernanda Ana-Sosa-Batiz, Dawid S Zyla, Stephanie S Harkins, Sujan Shresta

Cell Rep· May 2023

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SARS-CoV-2 Omicron (B.1.1.529) shows minimal neurotropism in a double-humanized mouse model.
Rubens Prince Dos Santos Alves, Ying-Ting Wang, Zbigniew Mikulski, Sara McArdle, Norazizah Shafee, Sujan Shresta

Antiviral Res· April 2023

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Mouse models of Zika virus transplacental transmission.
Qin Hui Li, Kenneth Kim, Sujan Shresta

Antiviral Res· February 2023

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SREBP2-dependent lipid gene transcription enhances the infection of human dendritic cells by Zika virus.
Emilie Branche, Ying-Ting Wang, Karla M Viramontes, Joan M Valls Cuevas, Jialei Xie, Sujan Shresta

Nat Commun· September 2022

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Acute-phase Serum Cytokine Levels and Correlation with Clinical Outcomes in Children and Adults with Primary and Secondary Dengue Virus Infection in Myanmar between 2017 and 2019.
Khine Mya Nwe, Mya Myat Ngwe Tun, Theingi Win Myat, Chris Fook Sheng Ng, Moh Moh Htun, Sujan Shresta

Pathogens· May 2022

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A Zika virus mutation enhances transmission potential and confers escape from protective dengue virus immunity.
Jose Angel Regla-Nava, Ying-Ting Wang, Camila R Fontes-Garfias, Yang Liu, Thasneem Syed, Sujan Shresta

Cell Rep· April 2022

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The Ability of Zika virus Intravenous Immunoglobulin to Protect From or Enhance Zika Virus Disease.
Amelia K Pinto, Mariah Hassert, Xiaobing Han, Douglas Barker, Trevor Carnelley, Sujan Shresta

Front Immunol· December 2021

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SARS-CoV-2 monoclonal antibodies with therapeutic potential: Broad neutralizing activity and No evidence of antibody-dependent enhancement.
Ying-Ting Wang, Robert D Allen, Kenneth Kim, Norazizah Shafee, Andrew J Gonzalez, Sujan Shresta

Antiviral Res· November 2021

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