Publications by authors named "Suling Huang"

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Cassane diterpenoids with hepatic gluconeogenesis inhibitory activity from the seeds of Caesalpinia decapetala (Roth) Alston.
De-Sheng Wang, Yu Shen, Lin-Fen Ding, Run-Cheng Yan, Ming Hu, Suling Huang

Phytochemistry· December 2025

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Dehydrotrametenolic acid methyl ester, a triterpenoid of Poria cocos, alleviates non-alcoholic steatohepatitis by suppressing NLRP3 inflammasome activation via targeting Caspase-1 in mice.
Ling-Yan Xia, Nai-Rong Yu, Su-Ling Huang, Hui Qu, Li Qin

Acta Pharmacol Sin· October 2025

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Clerodane diterpenoids from the vine stems of Fibraurea recisa Pierre and their hepatic gluconeogenesis inhibitory activity.
Hai-Yin Wang, Yu Shen, Wei Nie, Wen-Chao Tu, Suling Huang

Phytochemistry· April 2025

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Activation of SIK1 by phanginin A regulates skeletal muscle glucose uptake by phosphorylating HADC4/5/7 and enhancing GLUT4 expression and translocation.
Yu Shi, Xing-de Wu, Yanli Liu, Yu Shen, Hui Qu, Suling Huang

Nat Prod Bioprospect· April 2025

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A novel TGR5 agonist Sauchinone ameliorates IMQ induced murine psoriasis by regulating macrophage polarization.
Hao-Yu Wang, Su-Ling Huang, Jing Ren, Li-Yan Peng, Lin-Rui Chen

J Adv Res· April 2025

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Design, synthesis and biological evaluation of Alisol B derivatives for potential treatment of non-alcoholic steatohepatitis.
Nai-Rong Yu, Suling Huang, Zhen-Tao Deng, Jiayue Wang, Yu Shen

Bioorg Chem· February 2025

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Magnetic/Acoustic Dual-Controlled Microrobot Overcoming Oto-Biological Barrier for On-Demand Multidrug Delivery against Hearing Loss.
Xinyang Yi, Lifang Guo, Qi Zeng, Suling Huang, Dingsheng Wen

Small· November 2024

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A new mechanism of thyroid hormone receptor β agonists ameliorating nonalcoholic steatohepatitis by inhibiting intestinal lipid absorption via remodeling bile acid profiles.
Kai Sun, Nan-Lin Zhu, Su-Ling Huang, Hui Qu, Yi-Pei Gu

Acta Pharmacol Sin· October 2024

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Coronarin A modulated hepatic glycogen synthesis and gluconeogenesis via inhibiting mTORC1/S6K1 signaling and ameliorated glucose homeostasis of diabetic mice.
Su-Ling Huang, Wei Xie, Yang-Liang Ye, Jia Liu, Hui Qu

Acta Pharmacol Sin· March 2023

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Phenotypic screening-based drug discovery of furan-2-carboxylic acid derivatives for the amelioration of type 2 diabetes mellitus (T2DM).
Lili Chen, Suling Huang, Yangliang Ye, Yu Shen, Tifei Xu

Eur J Med Chem· January 2023

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Development and structure-activity relationships of tanshinones as selective 11β-hydroxysteroid dehydrogenase 1 inhibitors.
Xu Deng, Su-Ling Huang, Jian Ren, Zheng-Hong Pan, Yu Shen

Nat Prod Bioprospect· September 2022

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Spicatulides A-G, Phenolic-Monoterpenoid Hybrids from .
Jun-Su Zhou, Su-Ling Huang, Yuan Gao, Qun-Fang Liu, Ying Leng

J Nat Prod· August 2022

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Alisol B Alleviates Hepatocyte Lipid Accumulation and Lipotoxicity via Regulating RARα-PPARγ-CD36 Cascade and Attenuates Non-Alcoholic Steatohepatitis in Mice.
Zhuohui Zhao, Zhen-Tao Deng, Suling Huang, Mengmeng Ning, Ying Feng

Nutrients· June 2022

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Design, synthesis and structural-activity relationship studies of phanginin A derivatives for regulating SIK1-cAMP/CREB signaling to suppress hepatic gluconeogenesis.
Xing-De Wu, Suling Huang, Yu Shi, Yu Shen, Wen-Chao Tu

Eur J Med Chem· March 2022

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SL010110, a lead compound, inhibits gluconeogenesis via SIRT2-p300-mediated PEPCK1 degradation and improves glucose homeostasis in diabetic mice.
Yu-Ran Ren, Yang-Liang Ye, Ying Feng, Ti-Fei Xu, Yu Shen, Su-Ling Huang

Acta Pharmacol Sin· November 2021

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Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK.
Andris Elksnis, Tomas A Schiffer, Fredrik Palm, Yun Wang, Jing Cen, Suling Huang

Clin Sci (Lond)· October 2021

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Application of NRS2002 in Preoperative Nutritional Screening for Patients with Liver Cancer.
Suling Huang, Shijie Wang, Yuankang Xie, Xiao He, Xiuying Yi

J Oncol· August 2021

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A new mechanism of obeticholic acid on NASH treatment by inhibiting NLRP3 inflammasome activation in macrophage.
Suling Huang, Yanwei Wu, Zhuohui Zhao, Bing Wu, Kai Sun

Metabolism· July 2021

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Metabolomic Study of High-Fat Diet-Induced Obese (DIO) and DIO Plus CCl-Induced NASH Mice and the Effect of Obeticholic Acid.
Nanlin Zhu, Suling Huang, Qingli Zhang, Zhuohui Zhao, Hui Qu

Metabolites· June 2021

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An integrative drug repositioning framework discovered a potential therapeutic agent targeting COVID-19.
Yiyue Ge, Tingzhong Tian, Suling Huang, Fangping Wan, Jingxin Li

Signal Transduct Target Ther· April 2021

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Activation of SIK1 by phanginin A inhibits hepatic gluconeogenesis by increasing PDE4 activity and suppressing the cAMP signaling pathway.
Siwen Liu, Suling Huang, Xingde Wu, Ying Feng, Yu Shen

Mol Metab· November 2020

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TGR5 agonist ameliorates insulin resistance in the skeletal muscles and improves glucose homeostasis in diabetic mice.
Suling Huang, Shanyao Ma, Mengmeng Ning, Wenji Yang, Yangliang Ye

Metabolism· October 2019

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Linderane Suppresses Hepatic Gluconeogenesis by Inhibiting the cAMP/PKA/CREB Pathway Through Indirect Activation of PDE 3 via ERK/STAT3.
Wei Xie, Yangliang Ye, Ying Feng, Tifei Xu, Suling Huang

Front Pharmacol· May 2018

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Structural Elucidation and Bioinspired Total Syntheses of Ascorbylated Diterpenoid Hongkonoids A-D.
Jin-Xin Zhao, Yan-Yan Yu, Sha-Sha Wang, Su-Ling Huang, Yu Shen

J Am Chem Soc· February 2018

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Design and synthesis of Atglistatin derivatives as adipose triglyceride lipase inhibitors.
Jiyu Jin, Suling Huang, Lei Wang, Ying Leng, Wei Lu

Chem Biol Drug Des· December 2017

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