Publications by authors named "Sultan Chowdhury"

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Structure-Activity Relationship Study of Benzamides as QcrB Inhibitors.
Brock E Lynde, Jared Mattos, Danielle M Chemaly, Aditi Deshpande, Sreekanth Reddy Pogula, Sultan Chowdhury

ACS Med Chem Lett· August 2025

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New Triazolopyrimidines with Improved Activity against .
Sreekanth Reddy Pogula, Aditi Deshpande, Eric Greve, Sultan Chowdhury, Tanya Parish

ACS Med Chem Lett· June 2025

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Discovery of novel cyclopentane carboxylic acids as potent and selective inhibitors of Na1.7.
Shaoyi Sun, Sultan Chowdhury, Ivan Hemeon, Abid Hasan, Michael S Wilson

Bioorg Med Chem Lett· February 2025

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Novel 3-Aminothieno[2,3-]pyridine-2-carboxamides with Activity against .
Brock E Lynde, Danielle M Chemaly, Vanessa Pietrowski Baldin, Eric Greve, Christopher L Harding, Sultan Chowdhury

ACS Med Chem Lett· February 2025

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The contribution of Na1.6 to the efficacy of voltage-gated sodium channel inhibitors in wild type and Na1.6 gain-of-function (GOF) mouse seizure control.
James P Johnson, Thilo Focken, Parisa Karimi Tari, Celine Dube, Samuel J Goodchild, Sultan Chowdhury

Br J Pharmacol· October 2024

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Benzene Amide Ether Scaffold is Active against Non-replicating and Intracellular .
Sara Ahmed, Sultan Chowdhury, James Gomez, Deborah T Hung, Tanya Parish

ACS Infect Dis· October 2023

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Potent, Gut-Restricted Inhibitors of Divalent Metal Transporter 1: Preclinical Efficacy against Iron Overload and Safety Evaluation.
Alison Cutts, Sultan Chowdhury, Laszlo G Ratkay, Maryanne Eyers, Clint Young

J Pharmacol Exp Ther· July 2023

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Chemical Exploration of a Highly Selective Scaffold with Activity against Intracellular .
Samuel Njikan, Sara Ahmed, Alyssa Manning, Divya Awasthi, Yulia Ovechkina, Sultan Chowdhury

Microbiol Spectr· June 2022

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NBI-921352, a first-in-class, Na1.6 selective, sodium channel inhibitor that prevents seizures in gain-of-function mice, and wild-type mice and rats.
J P Johnson, Thilo Focken, Kuldip Khakh, Parisa Karimi Tari, Celine Dube, Sultan Chowdhury

Elife· March 2022

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Discovery of Acyl-sulfonamide Na1.7 Inhibitors GDC-0276 and GDC-0310.
Brian S Safina, Steven J McKerrall, Shaoyi Sun, Chien-An Chen, Sultan Chowdhury

J Med Chem· March 2021

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Identification of CNS-Penetrant Aryl Sulfonamides as Isoform-Selective Na1.6 Inhibitors with Efficacy in Mouse Models of Epilepsy.
Thilo Focken, Kristen Burford, Michael E Grimwood, Alla Zenova, Jean-Christophe Andrez, Sultan Chowdhury

J Med Chem· November 2019

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Structure- and Ligand-Based Discovery of Chromane Arylsulfonamide Na1.7 Inhibitors for the Treatment of Chronic Pain.
Steven J McKerrall, Teresa Nguyen, Kwong Wah Lai, Philippe Bergeron, Lunbin Deng, Sultan Chowdhury

J Med Chem· April 2019

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Identification of Selective Acyl Sulfonamide-Cycloalkylether Inhibitors of the Voltage-Gated Sodium Channel (Na) 1.7 with Potent Analgesic Activity.
Shaoyi Sun, Qi Jia, Alla Y Zenova, Michael S Wilson, Sultan Chowdhury

J Med Chem· January 2019

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Selective Na1.7 Antagonists with Long Residence Time Show Improved Efficacy against Inflammatory and Neuropathic Pain.
Girish Bankar, Samuel J Goodchild, Sarah Howard, Karen Nelkenbrecher, Matthew Waldbrook, Sultan Chowdhury

Cell Rep· September 2018

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Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N-([1,2,4]Triazolo[4,3- a]pyridin-3-yl)methane-sulfonamides as Potent and Selective hNa1.7 Inhibitors for the Treatment of Pain.
Thilo Focken, Sultan Chowdhury, Alla Zenova, Michael E Grimwood, Christine Chabot

J Med Chem· June 2018

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Discovery of Aryl Sulfonamides as Isoform-Selective Inhibitors of NaV1.7 with Efficacy in Rodent Pain Models.
Thilo Focken, Shifeng Liu, Navjot Chahal, Maxim Dauphinais, Michael E Grimwood, Sultan Chowdhury

ACS Med Chem Lett· March 2016

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Discovery of triazolone derivatives as novel, potent stearoyl-CoA desaturase-1 (SCD1) inhibitors.
Shaoyi Sun, Zaihui Zhang, Natalia Pokrovskaia, Sultan Chowdhury, Qi Jia

Bioorg Med Chem· February 2015

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The discovery of benzenesulfonamide-based potent and selective inhibitors of voltage-gated sodium channel Na(v)1.7.
Shaoyi Sun, Qi Jia, Alla Y Zenova, Mikhail Chafeev, Zaihui Zhang, Sultan Chowdhury

Bioorg Med Chem Lett· September 2014

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Systematic evaluation of amide bioisosteres leading to the discovery of novel and potent thiazolylimidazolidinone inhibitors of SCD1 for the treatment of metabolic diseases.
Shaoyi Sun, Zaihui Zhang, Vishnumurthy Kodumuru, Natalia Pokrovskaia, Julia Fonarev, Sultan Chowdhury

Bioorg Med Chem Lett· January 2014

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Discovery of piperazin-1-ylpyridazine-based potent and selective stearoyl-CoA desaturase-1 inhibitors for the treatment of obesity and metabolic syndrome.
Zaihui Zhang, Shaoyi Sun, Vishnumurthy Kodumuru, Duanjie Hou, Shifeng Liu, Sultan Chowdhury

J Med Chem· January 2013

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Discovery of benzylisothioureas as potent divalent metal transporter 1 (DMT1) inhibitors.
Zaihui Zhang, Vishnumurthy Kodumuru, Serguei Sviridov, Shifeng Liu, Mikhail Chafeev, Sultan Chowdhury

Bioorg Med Chem Lett· August 2012

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Discovery of XEN907, a spirooxindole blocker of NaV1.7 for the treatment of pain.
Sultan Chowdhury, Mikhail Chafeev, Shifeng Liu, Jianyu Sun, Vandna Raina

Bioorg Med Chem Lett· June 2011

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Synthesis and properties of a new member of the calixnaphthalene family: a C(2)-symmetrical endo-calix[4]naphthalene.
Sultan Chowdhury, Paris E Georghiou

J Org Chem· September 2002

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