Publications by authors named "Sumin Gu"

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Connexin Restrains EMT by Dual-Domain Mechanisms to Preserve Epithelial Identity.
Bo Ma, Zhaodan Ding, Guangyan Wang, Sumin Gu, Jean X Jiang

Res Sq· November 2025

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Mechano-activated connexin hemichannels mediate intercellular glutathione transport and support lens redox homeostasis.
Guangyan Wang, Yumeng Quan, Bo Ma, Sumin Gu, Jean X Jiang

Redox Biol· September 2025

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Correction: Identification of a disulfide bridge important for transport function of SNAT4 neutral amino acid transporter.
Rugmani Padmanabhan Iyer, Sumin Gu, Bruce J Nicholson, Jean X Jiang

PLoS One· July 2025

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Activation of connexin hemichannels enhances mechanosensitivity and anabolism in disused and aged bone.
Dezhi Zhao, Chao Tu, Lidan Zhang, Teja Guda, Sumin Gu

JCI Insight· December 2024

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Mechano-activated connexin hemichannels and glutathione transport protect lens fiber cells against oxidative insults.
Yuxin Tong, Guangyan Wang, Manuel A Riquelme, Yu Du, Yumeng Quan, Sumin Gu

Redox Biol· July 2024

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Antibody-activation of connexin hemichannels in bone osteocytes with ATP release suppresses breast cancer and osteosarcoma malignancy.
Manuel A Riquelme, Xuewei Wang, Francisca M Acosta, Jingruo Zhang, Jeffery Chavez, Sumin Gu, Guo Li

Cell Rep· July 2024

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Connexin hemichannels drive lactation-induced osteocyte acidification and perilacunar-canalicular remodeling.
Rui Hua, Vu A Truong, Roberto J Fajardo, Teja Guda, Sumin Gu

Cell Rep· July 2024

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Evaluation of Connexin Hemichannel Activity In Vivo.
Francisca M Acosta, Manuel A Riquelme, Sumin Gu, Jean X Jiang

Methods Mol Biol· April 2024

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Protocol for altering connexin hemichannel function in primary chicken lens fiber cells using high-titer retroviral RCAS(A) infection.
Yu Du, Francisca M Acosta, Jianping Zhang, Yuxin Tong, Yumeng Quan, Sumin Gu

STAR Protoc· December 2023

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Microinjection of Recombinant RCAS(A) Retrovirus into Embryonic Chicken Lens.
Francisca M Acosta, Bo Ma, Sumin Gu, Jean X Jiang

J Vis Exp· September 2023

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The second extracellular domain of connexin 50 is important for in cell adhesion, lens differentiation, and adhesion molecule expression.
Zhen Li, Yumeng Quan, Guangyan Wang, Bo Ma, Sumin Gu

J Biol Chem· March 2023

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Protein kinase A activation alleviates cataract formation via increased gap junction intercellular communication.
Yu Du, Yuxin Tong, Yumeng Quan, Guangyan Wang, Hongyun Cheng, Sumin Gu

iScience· March 2023

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Mechanosensitive piezo1 calcium channel activates connexin 43 hemichannels through PI3K signaling pathway in bone.
Yan Zeng, Manuel A Riquelme, Rui Hua, Jingruo Zhang, Francisca M Acosta, Sumin Gu

Cell Biosci· December 2022

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Connexin 43 hemichannels regulate mitochondrial ATP generation, mobilization, and mitochondrial homeostasis against oxidative stress.
Jingruo Zhang, Manuel A Riquelme, Rui Hua, Francisca M Acosta, Sumin Gu

Elife· November 2022

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Osteocytes regulate bone anabolic response to mechanical loading in male mice via activation of integrin α5.
Dezhi Zhao, Rui Hua, Manuel A Riquelme, Hongyun Cheng, Teja Guda, Sumin Gu

Bone Res· July 2022

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Connexin 43 Hemichannels Regulate Osteoblast to Osteocyte Differentiation.
Rui Hua, Sumin Gu, Jean X Jiang

Front Cell Dev Biol· May 2022

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Beyond the Channels: Adhesion Functions of Aquaporin 0 and Connexin 50 in Lens Development.
Zhen Li, Yumeng Quan, Sumin Gu, Jean X Jiang

Front Cell Dev Biol· April 2022

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Studying macrophage activation in immune-privileged lens through CSF-1 protein intravitreal injection in mouse model.
Yuting Li, Francisca M Acosta, Yumeng Quan, Zhen Li, Sumin Gu

STAR Protoc· March 2022

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Connexin hemichannels with prostaglandin release in anabolic function of bone to mechanical loading.
Dezhi Zhao, Manuel A Riquelme, Teja Guda, Chao Tu, Huiyun Xu, Sumin Gu

Elife· February 2022

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Data on Connexin 43 hemichannels regulation of cellular redox in lens.
Yumeng Quan, Yu Du, Changrui Wu, Sumin Gu, Jean X Jiang

Data Brief· December 2021

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Connexin hemichannels regulate redox potential via metabolite exchange and protect lens against cellular oxidative damage.
Yumeng Quan, Yu Du, Changrui Wu, Sumin Gu, Jean X Jiang

Redox Biol· October 2021

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ATP Inhibits Breast Cancer Migration and Bone Metastasis through Down-Regulation of CXCR4 and Purinergic Receptor P2Y11.
Xiaowen Liu, Manuel A Riquelme, Yi Tian, Dezhi Zhao, Francisca M Acosta, Sumin Gu

Cancers (Basel)· August 2021

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Connexin Gap Junctions and Hemichannels in Modulating Lens Redox Homeostasis and Oxidative Stress in Cataractogenesis.
Yumeng Quan, Yu Du, Yuxin Tong, Sumin Gu, Jean X Jiang

Antioxidants (Basel)· August 2021

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Macrophage recruitment in immune-privileged lens during capsule repair, necrotic fiber removal, and fibrosis.
Yuting Li, Zhen Li, Yumeng Quan, Hongyun Cheng, Manuel A Riquelme, Sumin Gu

iScience· June 2021

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Development of a potent embryonic chick lens model for studying congenital cataracts in vivo.
Zhen Li, Sumin Gu, Yumeng Quan, Kulandaiappan Varadaraj, Jean X Jiang

Commun Biol· March 2021

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