Publications by authors named "Sumito Ito"

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Generation and application of CES1-knockout Tet-Off-regulated CYP3A4 and UGT1A1-expressing Caco-2 cells.
Michika Murata, Kentaro Okada, Masaki Takahashi, Yukiko Ueyama-Toba, Sumito Ito

Toxicol Lett· November 2024

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Generation of tetracycline-controllable CYP3A4-expressing Caco-2 cells by the piggyBac transposon system.
Moe Ichikawa, Hiroki Akamine, Michika Murata, Sumito Ito, Kazuo Takayama

Sci Rep· June 2021

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Transient, Tunable Expression of NTCP and BSEP in MDCKII Cells for Kinetic Delineation of the Rate-Determining Process and Inhibitory Effects of Rifampicin in Hepatobiliary Transport of Taurocholate.
Sumito Ito, Wooin Lee, Ji Eun Park, Masa Yasunaga, Ayano Mori

J Pharm Sci· January 2021

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Generation of Human iPSC-Derived Intestinal Epithelial Cell Monolayers by CDX2 Transduction.
Kazuo Takayama, Ryosuke Negoro, Tomoki Yamashita, Kanae Kawai, Moe Ichikawa, Sumito Ito

Cell Mol Gastroenterol Hepatol· July 2020

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Investigation of non-linear Mate1-mediated efflux of trimethoprim in the mouse kidney as the mechanism underlying drug-drug interactions between trimethoprim and organic cations in the kidney.
Tomoko Kito, Sumito Ito, Tadahaya Mizuno, Kazuya Maeda, Hiroyuki Kusuhara

Drug Metab Pharmacokinet· February 2019

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Different Involvement of OAT in Renal Disposition of Oral Anticoagulants Rivaroxaban, Dabigatran, and Apixaban.
Yuri Tsuruya, Takeo Nakanishi, Hisakazu Komori, Xinying Wang, Naoki Ishiguro, Tomoko Kito, Sumito Ito

J Pharm Sci· September 2017

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Possible Role of Organic Cation Transporters in the Distribution of [C]Sulpiride, a Dopamine D Receptor Antagonist.
Harumasa Takano, Sumito Ito, Xuan Zhang, Hiroshi Ito, Ming-Rong Zhang

J Pharm Sci· September 2017

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Solute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2- Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug Penetration.
Houfu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang

Drug Metab Dispos· July 2015

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Evaluation of [(11)C]oseltamivir uptake into the brain during immune activation by systemic polyinosine-polycytidylic acid injection: a quantitative PET study using juvenile monkey models of viral infection.
Chie Seki, Arata Oh-Nishi, Yuji Nagai, Takafumi Minamimoto, Shigeru Obayashi, Takehito Ito, Hiroshi Ito, Mototsugu Ito, Sumito Ito

EJNMMI Res· July 2014

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Investigation of endogenous compounds for assessing the drug interactions in the urinary excretion involving multidrug and toxin extrusion proteins.
Koji Kato, Haruyuki Mori, Tomoko Kito, Miyu Yokochi, Sumito Ito

Pharm Res· January 2014

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Relationship between the urinary excretion mechanisms of drugs and their physicochemical properties.
Sumito Ito, Hirotaka Ando, Atsushi Ose, Yoshiaki Kitamura, Tomohiro Ando

J Pharm Sci· September 2013

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Drugs interacting with organic anion transporter-1 affect uptake of Tc-99m-mercaptoacetyl-triglycine (MAG3) in the human kidney: therapeutic drug interaction in Tc-99m-MAG3 diagnosis of renal function and possible application of Tc-99m-MAG3 for drug development.
Noriko Takahara, Tsuneo Saga, Masayuki Inubushi, Hiroyuki Kusuhara, Chie Seki, Sumito Ito

Nucl Med Biol· July 2013

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Association of multidrug resistance-associated protein 2 single nucleotide polymorphism rs12762549 with the basal plasma levels of phase II metabolites of isoflavonoids in healthy Japanese individuals.
Koji Kato, Hiroyuki Kusuhara, Yuji Kumagai, Ichiro Ieiri, Haruyuki Mori, Sumito Ito

Pharmacogenet Genomics· May 2012

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Competitive inhibition of the luminal efflux by multidrug and toxin extrusions, but not basolateral uptake by organic cation transporter 2, is the likely mechanism underlying the pharmacokinetic drug-drug interactions caused by cimetidine in the kidney.
Sumito Ito, Hiroyuki Kusuhara, Miyu Yokochi, Junko Toyoshima, Katsuhisa Inoue

J Pharmacol Exp Ther· February 2012

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The ATP-binding cassette transporter BCRP1/ABCG2 plays a pivotal role in cardiac repair after myocardial infarction via modulation of microvascular endothelial cell survival and function.
Yasutomi Higashikuni, Julie Sainz, Kazuto Nakamura, Minoru Takaoka, Soichiro Enomoto, Sumito Ito

Arterioscler Thromb Vasc Biol· November 2010

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Potent and specific inhibition of mMate1-mediated efflux of type I organic cations in the liver and kidney by pyrimethamine.
Sumito Ito, Hiroyuki Kusuhara, Yushun Kuroiwa, Chunyong Wu, Yoshinori Moriyama

J Pharmacol Exp Ther· April 2010

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