Publications by authors named "Surajit Sinha"

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4
4'-O-methoxyethyl-2'-deoxy-uridine and cytidine ribonucleotides improve duplex stability, nuclease resistance, and elicit efficient knockdown of Bcl-2 expression.
Sumit Gangopadhyay, Gourav Das, Swrajit Nath Sharma, Atanu Ghosh, Siddharam Shivappa Bagale, Surajit Sinha

Bioorg Med Chem Lett· December 2025

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Antibody-Mediated Inhibition of HLA/LILR Interactions Breaks Innate Immune Tolerance and Induces Antitumor Immunity.
Abir K Panda, Kannan Natarajan, Surajit Sinha, Jiansheng Jiang, Sruthi Chempati

Cancer Immunol Res· December 2025

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A rebrand for proteasome inhibition in solid tumors via continuous hepatic artery infusion.
Carolina M Larrain, Jack H Victory, Priyanka P Desai, Lindsay R Friedman, Hannah Stepp, Surajit Sinha

JCI Insight· December 2025

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A simple circuit to sustain intact tumor microenvironments for complex drug interrogations.
A Leila Sarvestani, Samantha Ruff, Kirsten Remmert, Martha Teke, Emily Verbus, Surajit Sinha

bioRxiv· October 2025

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Guanidinium-linked morpholino-siRNA chimera: synthesis, biophysical properties and activity.
Shalini Gupta, Atanu Ghosh, Subhamoy Pratihar, Maria Mukherjee, Jayanta Kundu, Surajit Sinha

Chem Commun (Camb)· September 2025

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Expression of IMPACT Curtails Metabolic Plasticity and Augments NK Cell Killing to Abrogate Metastatic Growth.
Surajit Sinha, Abir Kumar Panda, Rodrigo Xavier das Neves, Zeribe C Nwosu, Ke Xu

Cancer Discov· September 2025

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Enhanced G-Quadruplex Stability and Anticancer Activity of -Aryl Deoxyguanosine-Modified T40214 Oligonucleotides Targeting STAT3 in Prostate Cancer.
Nishant Kumar Choudhary, Swrajit Nath Sharma, Gourav Das, Atanu Ghosh, Siddharam Shivappa Bagale, Surajit Sinha

Biochemistry· August 2025

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Thermodynamic Destabilization and Structural Adaptability of 2'-Alkoxy/Fluoro--Methyl Pyrimidine Nucleotides in siRNA Enhance RNA Interference Activity.
Avijit Sahoo, Shalini Gupta, Gourav Das, Swrajit Nath Sharma, Atanu Ghosh, Surajit Sinha

J Med Chem· August 2025

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Wireless Uncaging of Boronates in Living Cells via Piezocatalytically Generated HO.
Jayanta Dolai, Atanu Ghosh, Reeddhi Ray, Abu Raihan Sarkar, Anupam Maity, Surajit Sinha

ACS Appl Mater Interfaces· July 2025

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Expression of IMPACT curtails metabolic plasticity and augments NK cell killing to abrogate metastatic growth.
Surajit Sinha, Abir Kumar Panda, Rodrigo Xavier das Neves, Zeribe C Nwosu, Ke Xu

Cancer Discov· July 2025

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An Open-Source Normothermic Perfusion System Designed for Research Scientists.
Lindsay R Friedman, Hannah E Stepp, Jacob Lambdin, Allen Luna, Alexander Rossi, Surajit Sinha

J Vis Exp· July 2025

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4'--Cholesterol/Pyridyl-2'--Methyl Uridine-Functionalized siRNA Enhances Stability and Carrier-Free Gene Silencing.
Santanu Sar, Shalini Gupta, Gourav Das, Swrajit Nath Sharma, Deepak K, Surajit Sinha

Bioconjug Chem· June 2025

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Phosphoramidite Platform for the Automated Synthesis of Morpholino Antisense Oligonucleotides and Their Chimeras.
Atanu Ghosh, Maria Mukherjee, Arpan Banerjee, Shreyasi Acharya, Surajit Sinha

Curr Protoc· June 2025

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Site-Specific Chemical Modulation of a Flexible Azaproline Transporter to Enhance Epirubicin Accumulation in Drug-Resistant Human Glioblastoma Cells and Blood-Brain Barrier Penetration in Adult Zebrafish.
Abhishek Gupta, Pallab Shaw, Swrajit Nath Sharma, Shalini Gupta, Surajit Sinha

Mol Pharm· May 2025

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Chemical Insights into Oligonucleotide-Protein Binding for Therapeutic Applications.
Shalini Gupta, Abhishek Gupta, Maria Mukherjee, Sritama Bose, Surajit Sinha

J Med Chem· May 2025

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Optochemical control over mRNA translation by photocaged phosphorodiamidate morpholino oligonucleotides in vivo.
Katsiaryna Tarbashevich, Atanu Ghosh, Arnab Das, Debajyoti Kuilya, Swrajit Nath Sharma, Surajit Sinha

Nat Commun· April 2025

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A Unified Phosphoramidite Platform for the Synthesis of Morpholino Oligonucleotides and Diverse Chimeric Backbones.
Atanu Ghosh, Arpan Banerjee, Shalini Gupta, Surajit Sinha

J Am Chem Soc· December 2024

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Selective Recognition of the Dimeric NG16 Parallel G-Quadruplex Structure Using Synthetic Turn-On Red Fluorescent Protein Chromophore.
Nishant Kumar Choudhary, Shalini Gupta, Gourav Das, Avijit Sahoo, S Harikrishna, Surajit Sinha

Biochemistry· November 2024

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Benzofuran Iboga-Analogs Modulate Nociception and Inflammation in an Acute Mouse Pain Model.
Tuhin Bhattacharya, Abhishek Gupta, Shalini Gupta, Samrat Saha, Shatabdi Ghosh, Surajit Sinha

Chembiochem· August 2024

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Total Synthesis of Lipopeptide Bacilotetrin C: Discovery of Potent Anticancer Congeners Promoting Autophagy.
Sourya Shankar Auddy, Shalini Gupta, Subrata Mandi, Himangshu Sharma, Surajit Sinha

ACS Med Chem Lett· August 2024

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2'--Alkyl- -Methyluridine Functionalized Passenger Strand Improves RNAi Activity by Modulating the Thermal Stability.
Avijit Sahoo, Shalini Gupta, Gourav Das, Atanu Ghosh, Siddharam Shivappa Bagale, Surajit Sinha

ACS Med Chem Lett· August 2024

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Synthesis of Self Permeable Antisense PMO Using C5-Guanidino-Functionalized Pyrimidines at the 5'-End Enables Sox2 Downregulation in Triple Negative Breast Cancer Cells.
Arnab Das, Shalini Gupta, Pallab Shaw, Surajit Sinha

Mol Pharm· March 2024

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Synthesis and Biophysical Properties of Triazole-Incorporated PMOs (TzPMOs): A Convergent, Click Ligation Approach.
Arpan Banerjee, Arnab Das, Atanu Ghosh, Abhishek Gupta, Surajit Sinha

J Org Chem· March 2024

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4'--Acetamidomethyl-2'--methoxyethyl Nucleic Acid Modifications Improve Thermal Stability, Nuclease Resistance, Potency, and hAgo2 Binding of Small Interfering RNAs.
Sumit Gangopadhyay, Gourav Das, Shalini Gupta, Atanu Ghosh, Siddharam Shivappa Bagale, Surajit Sinha

J Org Chem· March 2024

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N-Methyluridine and 2'-O-Alkyl/2'-Fluoro-N-methyluridine functionalized nucleic acids improve nuclease resistance while maintaining duplex geometry.
Avijit Sahoo, Gourav Das, Atanu Ghosh, Siddharam Shivappa Bagale, Nishant Kumar Choudhary, Surajit Sinha

Bioorg Med Chem· February 2024

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