Publications by authors named "Susan Christner"

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Phase 1 clinical trial of the ataxia telangiectasia and Rad3-related inhibitor berzosertib with irinotecan in patients with advanced solid tumors (ETCTN 9938).
Liza C Villaruz, Jingxiao Jin, Hong Wang, James J Lee, Jason J Luke, Susan M Christner

Cancer· November 2025

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Phase Ib study of berzosertib, carboplatin, gemcitabine, and pembrolizumab in patients with squamous nonsmall lung cancer (ETCTN 10313).
Liza C Villaruz, Benjamin Schluger, Hong Wang, James Ohr, Daniel Petro, Susan M Christner

Oncologist· November 2025

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Quantitation of Niraparib in Human Plasma by LC-MS/MS.
Tien V Le, Sarah E Taylor, Robert A Parise, Susan M Christner, Cortney Montgomery

Biomed Chromatogr· September 2025

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Phase I trial of ATR inhibitor elimusertib with FOLFIRI in advanced or metastatic gastrointestinal malignancies (ETCTN 10406).
Anuradha Krishnamurthy, Hong Wang, John C Rhee, Diwakar Davar, Ryan H Moy, Susan M Christner

Cancer Chemother Pharmacol· January 2025

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Quantitation of the DNA-dependent protein kinase inhibitor peposertib (M3814) and metabolite in human plasma by LC-MS/MS.
Susan M Christner, Robert A Parise, Christopher J Bakkenist, S Lindsey Davis, Ye Feng

Biomed Chromatogr· December 2024

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Dose finding, bioavailability, and PK-PD of oral triapine with concurrent chemoradiation for locally advanced cervical cancer and vaginal cancer (ETCTN 9892).
Sarah E Taylor, Sarah Behr, Kristine L Cooper, Haider Mahdi, Denise Fabian, Susan M Christner

Cancer Chemother Pharmacol· December 2024

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Mitigation of Fetal Radiation Injury from Mid-Gestation Total-body Irradiation by Maternal Administration of Mitochondrial-Targeted GS-Nitroxide JP4-039.
Yijen L Wu, Anthony G Christodoulou, Jan H Beumer, Lora H Rigatti, Renee Fisher, Susan M Christner

Radiat Res· September 2024

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Mitigation of Fetal Irradiation Injury from Mid-Gestation Total Body Radiation with Mitochondrial-Targeted GS-Nitroxide JP4-039.
Yijen L Wu, Anthony G Christodoulou, Jan H Beumer, Lora H Rigatti, Renee Fisher, Susan M Christner

bioRxiv· February 2024

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Tumor cell p38 inhibition to overcome immunotherapy resistance.
Jason J Luke, Rebekah E Dadey, Ryan C Augustin, Sarah Newman, Krishna B Singh, Susan M Christner

Res Sq· August 2023

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Dasatinib and dexamethasone followed by hematopoietic cell transplantation for adults with Ph-positive ALL.
Matthew J Wieduwilt, Jun Yin, Meir Wetzler, Geoffrey L Uy, Bayard L Powell, Susan M Christner

Blood Adv· November 2021

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Evaluation of the pharmacokinetic drug-drug interaction potential of iohexol, a renal filtration marker.
Anand Joshi, Jianxia Guo, Julianne L Holleran, Brian Kiesel, Sarah Taylor, Susan Christner

Cancer Chemother Pharmacol· October 2020

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Phase 1 study of the Aurora kinase A inhibitor alisertib (MLN8237) combined with the histone deacetylase inhibitor vorinostat in lymphoid malignancies.
Tanya Siddiqi, Paul Frankel, Jan H Beumer, Brian F Kiesel, Susan Christner

Leuk Lymphoma· February 2020

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Quantitation of paclitaxel, and its 6-alpha-OH and 3-para-OH metabolites in human plasma by LC-MS/MS.
Susan M Christner, Robert A Parise, Percy S Ivy, Hussein Tawbi, Edward Chu

J Pharm Biomed Anal· August 2019

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A window-of-opportunity clinical trial of dasatinib in women with newly diagnosed endometrial cancer.
Linda R Duska, Gina R Petroni, Heather Lothamer, William Faust, Jan H Beumer, Susan M Christner

Cancer Chemother Pharmacol· March 2019

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A phase-1 study of dasatinib plus all-trans retinoic acid in acute myeloid leukemia.
Robert L Redner, Jan H Beumer, Patricia Kropf, Mounzer Agha, Michael Boyiadzis, Susan M Christner

Leuk Lymphoma· November 2018

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Evaluation of Biodistribution of Sulforaphane after Administration of Oral Broccoli Sprout Extract in Melanoma Patients with Multiple Atypical Nevi.
Shawn Tahata, Shivendra V Singh, Yan Lin, Eun-Ryeong Hahm, Jan H Beumer, Susan M Christner

Cancer Prev Res (Phila)· July 2018

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Liquid chromatography-tandem mass spectrometric assay for the quantitation of the novel radiation protective agent and radiation mitigator JP4-039 in murine plasma.
Susan Christner, Jianxia Guo, Robert A Parise, Melanie Ringeval, Adam T Hoye

J Pharm Biomed Anal· February 2018

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Disease Subtype-Independent Biomarkers of Breast Cancer Chemoprevention by the Ayurvedic Medicine Phytochemical Withaferin A.
Suman K Samanta, Anuradha Sehrawat, Su-Hyeong Kim, Eun-Ryeong Hahm, Yongli Shuai, Susan M Christner

J Natl Cancer Inst· June 2017

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A phase I pharmacokinetic study of intraperitoneal bortezomib and carboplatin in patients with persistent or recurrent ovarian cancer: An NRG Oncology/Gynecologic Oncology Group study.
Danielle A Jandial, William E Brady, Stephen B Howell, Heather A Lankes, Russell J Schilder, Susan M Christner

Gynecol Oncol· May 2017

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Human hepatocyte assessment of imatinib drug-drug interactions - complexities in clinical translation.
Jan H Beumer, Venkateswaran C Pillai, Robert A Parise, Susan M Christner, Brian F Kiesel

Br J Clin Pharmacol· November 2015

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An Automated Homogeneous Immunoassay for Quantitating Imatinib Concentrations in Plasma.
Jan H Beumer, Daniel Kozo, Rebecca L Harney, Caitlin N Baldasano, Justin Jarrah, Susan M Christner

Ther Drug Monit· August 2015

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In vitro cytotoxicity and in vivo efficacy, pharmacokinetics, and metabolism of pyrazole-based small molecule inhibitors of Mdm2/4-p53 interaction.
Susan M Christner, Dana M Clausen, Jan H Beumer, Robert A Parise, Jianxia Guo

Cancer Chemother Pharmacol· August 2015

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Phase 2 trial of dasatinib in target-selected patients with recurrent glioblastoma (RTOG 0627).
Andrew B Lassman, Stephanie L Pugh, Mark R Gilbert, Kenneth D Aldape, Sandrine Geinoz, Susan M Christner

Neuro Oncol· July 2015

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Effect of age on the pharmacokinetics of busulfan in patients undergoing hematopoietic cell transplantation; an alliance study (CALGB 10503, 19808, and 100103).
Jan H Beumer, Kouros Owzar, Lionel D Lewis, Chen Jiang, Julianne L Holleran, Susan M Christner

Cancer Chemother Pharmacol· November 2014

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Quantitative method for the determination of iso-fludelone (KOS-1803) in human plasma by LC-MS/MS.
Susan M Christner, Robert A Parise, Erica D Levine, Naiyer A Rizvi, Mrinal M Gounder

J Pharm Biomed Anal· November 2014

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