Publications by authors named "Susan Hubchak"

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Inositol-requiring enzyme 1α/X-box protein 1 pathway expression is impaired in pediatric cholestatic liver disease explants.
Alyssa Kriegermeier, Angela Hyon, Brian LeCuyer, Susan Hubchak, Xiaoying Liu

PLoS One· December 2022

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Hepatic Deletion of X-Box Binding Protein 1 in FXR Null Mice Leads to Enhanced Liver Injury.
Xiaoying Liu, Mahmoud Khalafalla, Chuhan Chung, Yevgeniy Gindin, Susan Hubchak

J Lipid Res· November 2022

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Mechanisms of liver injury in high fat sugar diet fed mice that lack hepatocyte X-box binding protein 1.
Xiaoying Liu, Sarah A Taylor, Kyle D Gromer, Danny Zhang, Susan C Hubchak

PLoS One· February 2022

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Hepatic X-Box Binding Protein 1 and Unfolded Protein Response Is Impaired in Weanling Mice With Resultant Hepatic Injury.
Alyssa Kriegermeier, Angela Hyon, Meredith Sommars, Susan Hubchak, Brian LeCuyer

Hepatology· December 2021

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Farnesoid X receptor signaling activates the hepatic X-box binding protein 1 pathway in vitro and in mice.
Xiaoying Liu, Grace L Guo, Bo Kong, David B Hilburn, Susan C Hubchak

Hepatology· July 2018

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Hepatic deletion of X-box binding protein 1 impairs bile acid metabolism in mice.
Xiaoying Liu, Anne S Henkel, Brian E LeCuyer, Susan C Hubchak, Matthew J Schipma

J Lipid Res· March 2017

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Epidermal growth factor inhibits transforming growth factor-β-induced fibrogenic differentiation marker expression through ERK activation.
Xiaoying Liu, Susan C Hubchak, James A Browne, H William Schnaper

Cell Signal· October 2014

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Hypoxia-inducible factor-2α and TGF-β signaling interact to promote normoxic glomerular fibrogenesis.
Christian Hanna, Susan C Hubchak, Xiaoyan Liang, Benaya Rozen-Zvi, Paul T Schumacker

Am J Physiol Renal Physiol· November 2013

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TGF-β/Smad3 activates mammalian target of rapamycin complex-1 to promote collagen production by increasing HIF-1α expression.
Benaya Rozen-Zvi, Tomoko Hayashida, Susan C Hubchak, Christian Hanna, Leonidas C Platanias

Am J Physiol Renal Physiol· August 2013

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Interdependence of HIF-1α and TGF-β/Smad3 signaling in normoxic and hypoxic renal epithelial cell collagen expression.
Rajit K Basu, Susan Hubchak, Tomoko Hayashida, Constance E Runyan, Paul T Schumacker

Am J Physiol Renal Physiol· April 2011

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A conceptual framework for the molecular pathogenesis of progressive kidney disease.
H William Schnaper, Susan C Hubchak, Constance E Runyan, James A Browne, Gal Finer

Pediatr Nephrol· November 2010

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Rac1 promotes TGF-beta-stimulated mesangial cell type I collagen expression through a PI3K/Akt-dependent mechanism.
Susan C Hubchak, Erin E Sparks, Tomoko Hayashida, H William Schnaper

Am J Physiol Renal Physiol· November 2009

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Role of SARA (SMAD anchor for receptor activation) in maintenance of epithelial cell phenotype.
Constance E Runyan, Tomoko Hayashida, Susan Hubchak, Jessica F Curley, H William Schnaper

J Biol Chem· September 2009

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TGF-beta signal transduction in chronic kidney disease.
H William Schnaper, Sara Jandeska, Constance E Runyan, Susan C Hubchak, Rajit K Basu

Front Biosci (Landmark Ed)· January 2009

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Hypoxia regulates PDGF-B interactions between glomerular capillary endothelial and mesangial cells.
Eudora Eng, Cory Holgren, Susan Hubchak, Parveen Naaz, H William Schnaper

Kidney Int· August 2005

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Cytoskeletal rearrangement and signal transduction in TGF-beta1-stimulated mesangial cell collagen accumulation.
Susan C Hubchak, Constance E Runyan, Jeffrey I Kreisberg, H William Schnaper

J Am Soc Nephrol· August 2003

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TGF-beta signal transduction and mesangial cell fibrogenesis.
H William Schnaper, Tomoko Hayashida, Susan C Hubchak, Anne-Christine Poncelet

Am J Physiol Renal Physiol· February 2003

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