Publications by authors named "Susan Laffan"

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Teratogenic Risk Impact Mitigation (TRIM): Development of Explicit Criteria to Facilitate Decisions Regarding Teratogenic Risk Mitigation Strategies.
Celeste L Y Ewig, Yanning Wang, Nicole E Smolinski, Gita A Toyserkani, Cynthia LaCivita, Susan B Laffan

Drug Saf· December 2025

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Brain Weight Effect of Ambrisentan in Juvenile Rat Toxicity Studies Associated With Breathing Sounds, Apnea, and Sustained Hypoxemia.
Susan B Laffan, Kohrs Loren, Kambara Takahito, Turner Sandra

Birth Defects Res· July 2025

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Weight of Evidence: Is an Animal Study Warranted? Assessments for Carcinogenicity, Drug Abuse Liability, and Pediatric Safety.
Thulasi Ramani, Ronald L Wange, T Scott Manetz, Paul J Kruzich, Susan B Laffan

Int J Toxicol· September 2024

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Novel Bacterial Topoisomerase Inhibitor Gepotidacin Demonstrates Absence of Fluoroquinolone-Like Arthropathy in Juvenile Rats.
Cindy Fishman, Jessica M Caverly Rae, Lorraine M Posobiec, Susan B Laffan, Steven A Lerman

Antimicrob Agents Chemother· November 2022

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The benefits, limitations and opportunities of preclinical models for neonatal drug development.
Sarah Campion, Amy Inselman, Belinda Hayes, Costanza Casiraghi, David Joseph, Susan Laffan

Dis Model Mech· April 2022

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Dose range finding approach for rodent preweaning juvenile animal studies.
Lorraine M Posobiec, Susan B Laffan

Birth Defects Res· March 2021

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The exploration of aza-quinolines as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors with low brain exposure.
Rodolfo Cadilla, David N Deaton, Young Do, Patricia A Elkins, Daniela Ennulat, Susan B Laffan

Bioorg Med Chem· December 2020

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Immune complex disease in a chronic monkey study with a humanised, therapeutic antibody against CCL20 is associated with complement-containing drug aggregates.
Susan B Laffan, Andrew S Thomson, Shing Mai, Cindy Fishman, Takahito Kambara

PLoS One· July 2020

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Absence of developmental and reproductive toxicity in animals exposed to dolutegravir.
Dinesh J Stanislaus, Lorraine M Posobiec, Susan B Laffan, Howard M Solomon, Mary K Ziejewski

Birth Defects Res· February 2020

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Species Comparison of Postnatal Development of the Female Reproductive System.
Susan B Laffan, Lorraine M Posobiec, Jenny E Uhl, Justin D Vidal

Birth Defects Res· February 2018

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Comparing rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on systemic dose and developmental effects.
Peter T Theunissen, Sonia Beken, Bruce Beyer, William J Breslin, Gregg D Cappon, Susan B Laffan

Crit Rev Toxicol· May 2017

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Comparison of rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on the nature and severity of developmental effects.
Peter T Theunissen, Sonja Beken, Bruce K Beyer, William J Breslin, Gregg D Cappon, Susan B Laffan

Crit Rev Toxicol· November 2016

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Early Vaginal Opening in Juvenile Female Rats Given BRAF-Inhibitor Dabrafenib Is Not Associated with Early Physiologic Sexual Maturation.
Lorraine M Posobiec, Justin D Vidal, Angela Hughes-Earle, Susan B Laffan, Timothy Hart

Birth Defects Res B Dev Reprod Toxicol· December 2015

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Imaging MS in Toxicology: An Investigation of Juvenile Rat Nephrotoxicity Associated with Dabrafenib Administration.
M Reid Groseclose, Susan B Laffan, Kendall S Frazier, Angela Hughes-Earle, Stephen Castellino

J Am Soc Mass Spectrom· June 2015

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The spirit of nursing.
Susan Laffan

Nursing· April 2015

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Memorable moments.
Susan Laffan

Nursing· December 2014

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Dihydroartemisinin (DHA) treatment causes an arrest of cell division and apoptosis in rat embryonic erythroblasts in whole embryo culture.
Lorraine M Posobiec, Robert L Clark, Paul B Bushdid, Susan B Laffan, Kai-Fen Wang

Birth Defects Res B Dev Reprod Toxicol· December 2013

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The inhibin B response to a motilin receptor agonist in male rats.
Mary K Ziejewski, Justin D Vidal, Dinesh Stanislaus, April Apostoli, Probash Chowdhury, Susan Laffan

Birth Defects Res B Dev Reprod Toxicol· February 2013

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Summary of the HESI consortium studies exploring circulating inhibin B as a potential biomarker of testis damage in the rat.
Robert Chapin, Gerhard Weinbauer, Michael S Thibodeau, Manisha Sonee, Louise Parks Saldutti, Susan Laffan

Birth Defects Res B Dev Reprod Toxicol· February 2013

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Assessing a theoretical risk of dolutegravir-induced developmental immunotoxicity in juvenile rats.
Melissa Rhodes, Susan Laffan, Caroline Genell, Jill Gower, Curtis Maier

Toxicol Sci· November 2012

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Artesunate-induced depletion of embryonic erythroblasts precedes embryolethality and teratogenicity in vivo.
Tacey E K White, Paul B Bushdid, Sandra Ritter, Susan B Laffan, Robert L Clark

Birth Defects Res B Dev Reprod Toxicol· October 2006

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The 'inside look' on correctional nursing: a unique nursing speciality.
Susan Laffan

N J Nurse· May 2005

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Job satisfaction and the effects of the current nationwide nursing shortage.
Susan Laffan

N J Nurse· November 2002

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