Publications by authors named "Susan Leed"

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Optimization of Prodiginines as Single-Dose Curative Antimalarials.
Amrendra Kumar, Yuexin Li, Xiaowei Zhang, Mahesh Gaddam, Diana Caridha, Susan Leed

J Med Chem· November 2025

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Acridone Prodrugs with Enhanced Dual-Stage Antimalarial Efficacy.
Rozalia A Dodean, Yuexin Li, Xiaowei Zhang, Amrendra Kumar, Sovitj Pou, Susan Leed

ACS Med Chem Lett· July 2025

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Optimization of Tambjamines Active against Multiple Stages of Malaria Parasites.
Amrendra Kumar, Yuexin Li, Xiaowei Zhang, Xiannu Jin, William E Dennis, Susan Leed

J Med Chem· June 2025

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In vitro activity and in vivo efficacy of omadacycline against Plasmodium species.
Michael S Madejczyk, Susan E Leed, Karl Kudyba, Alison Roth, Monica L Martin

Malar J· June 2025

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Potent Acridone Antimalarial against All Three Life Stages of .
Papireddy Kancharla, Rozalia A Dodean, Yuexin Li, Xiaowei Zhang, Sean Kelly, Susan Leed

Res Sq· June 2025

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Development of Next-Generation Antimalarial Acridones with Radical Cure Potential.
Rozalia A Dodean, Yuexin Li, Xiaowei Zhang, Diana Caridha, Michael S Madejczyk, Susan Leed

J Med Chem· April 2025

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Identification of Substituted 4-Aminocinnolines as Broad-Spectrum Antiparasitic Agents.
Andrew Spaulding, Amrita Sharma, Miriam A Giardini, Benjamin Hoffman, Jean A Bernatchez, Susan E Leed

ACS Infect Dis· March 2025

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Tambjamines as Fast-Acting Multistage Antimalarials.
Amrendra Kumar, Yuexin Li, Rozalia A Dodean, Alison Roth, Diana Caridha, Susan Leed

ACS Infect Dis· December 2024

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Optimization of B-Ring-Functionalized Antimalarial Tambjamines and Prodiginines.
Amrendra Kumar, Sivanna Chithanna, Yuexin Li, Xiaowei Zhang, Rozalia A Dodean, Susan Leed

J Med Chem· November 2024

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Novel hydrazone compounds with broad-spectrum antiplasmodial activity and synergistic interactions with antimalarial drugs.
Angélica M Rosado-Quiñones, Emilee E Colón-Lorenzo, Zarna Rajeshkumar Pala, Jürgen Bosch, Karl Kudyba, Susan E Leed

Antimicrob Agents Chemother· June 2024

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Discovery and Optimization of Tambjamines as a Novel Class of Antileishmanial Agents.
Papireddy Kancharla, Diana Ortiz, Corinne M Fargo, Xiaowei Zhang, Yuexin Li, Susan Leed

J Med Chem· May 2024

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Combination of Subtherapeutic Doses of Tretazicar and Liposomal Amphotericin B Suppresses and Cures -Induced Cutaneous Lesions in Murine Models.
Diana Caridha, Richard J Sciotti, Jason Sousa, Brian Vesely, Tesfaye Teshome, Susan Leed

ACS Infect Dis· February 2021

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In Vivo Bioluminescent Monitoring of Parasites in BALB/c Mouse Models of Cutaneous Leishmaniasis Drug Discovery.
Diana Caridha, Susan Leed, Alicia Cawlfield

Methods Mol Biol· December 2020

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Lead Optimization of Second-Generation Acridones as Broad-Spectrum Antimalarials.
Papireddy Kancharla, Rozalia A Dodean, Yuexin Li, Sovitj Pou, Brandon Pybus, Susan E Leed

J Med Chem· June 2020

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Scaffold and Parasite Hopping: Discovery of New Protozoal Proliferation Inhibitors.
Baljinder Singh, Jean A Bernatchez, Laura-Isobel McCall, Claudia M Calvet, Jasmin Ackermann, Susan E Leed

ACS Med Chem Lett· March 2020

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Novel benzoxaborole, nitroimidazole and aminopyrazoles with activity against experimental cutaneous leishmaniasis.
Katrien Van Bocxlaer, Diana Caridha, Chad Black, Brian Vesely, Susan Leed

Int J Parasitol Drugs Drug Resist· December 2019

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Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials.
Rozalia A Dodean, Papireddy Kancharla, Yuexin Li, Victor Melendez, Lisa Read, Susan E Leed

J Med Chem· April 2019

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Updating the modified Thompson test by using whole-body bioluminescence imaging to replace traditional efficacy testing in experimental models of murine malaria.
Diana Caridha, Mark Hickman, Lisa Xie, Franklyn Ngundam, Erin Milner, Susan Leed

Malar J· February 2019

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Anilinoquinoline based inhibitors of trypanosomatid proliferation.
Lori Ferrins, Amrita Sharma, Sarah M Thomas, Naimee Mehta, Jessey Erath, Susan E Leed

PLoS Negl Trop Dis· November 2018

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Series of Alkynyl-Substituted Thienopyrimidines as Inhibitors of Protozoan Parasite Proliferation.
Jennifer L Woodring, Ranjan Behera, Amrita Sharma, Justin Wiedeman, Gautam Patel, Susan E Leed

ACS Med Chem Lett· October 2018

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Corrigendum to "Optimization of physicochemical properties for 4-Anilinoquinazoline inhibitors of trypanosome proliferation" [Eur. J. Med. Chem. 141 (2017) 446-459].
Jennifer L Woodring, Kelly A Bachovchin, Kimberly G Brady, Mitchell F Gallerstein, Jessey Erath, Susan E Leed

Eur J Med Chem· May 2018

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Optimization of Physicochemical Properties for 4-Anilinoquinoline Inhibitors of Plasmodium falciparum Proliferation.
Naimee Mehta, Lori Ferrins, Susan E Leed, Richard J Sciotti, Michael P Pollastri

ACS Infect Dis· April 2018

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Optimization of physicochemical properties for 4-anilinoquinazoline inhibitors of trypanosome proliferation.
Jennifer L Woodring, Kelly A Bachovchin, Kimberly G Brady, Mitchell F Gallerstein, Jessey Erath, Susan E Leed

Eur J Med Chem· December 2017

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Use of Optical Imaging Technology in the Validation of a New, Rapid, Cost-Effective Drug Screen as Part of a Tiered Screening Paradigm for Development of Drugs To Treat Cutaneous Leishmaniasis.
Diana Caridha, Sandi Parriot, Thomas H Hudson, Thierry Lang, Franklyn Ngundam, Susan Leed

Antimicrob Agents Chemother· April 2017

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Antiparasitic Lead Discovery: Toward Optimization of a Chemotype with Activity Against Multiple Protozoan Parasites.
William Devine, Sarah M Thomas, Jessey Erath, Kelly A Bachovchin, Patricia J Lee, Susan E Leed

ACS Med Chem Lett· March 2017

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