Publications by authors named "Susan O Meakin"

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TrkB Regulates N-Methyl-D-Aspartate Receptor Signaling by Uncoupling and Recruiting the Brain-Specific Guanine Nucleotide Exchange Factor, RasGrf1.
Asghar Talebian, Kim Robinson-Brookes, Susan O Meakin

J Mol Neurosci· January 2019

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Signaling adaptor ShcD suppresses extracellular signal-regulated kinase (Erk) phosphorylation distal to the Ret and Trk neurotrophic receptors.
Melanie K B Wills, Ava Keyvani Chahi, Hayley R Lau, Manali Tilak, Brianna D Guild, Susan O Meakin

J Biol Chem· April 2017

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Unravelling the Mechanism of TrkA-Induced Cell Death by Macropinocytosis in Medulloblastoma Daoy Cells.
Chunhui Li, James I S MacDonald, Asghar Talebian, Jennifer Leuenberger, Claudia Seah, Susan O Meakin

Mol Cell Biol· October 2016

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Arf6 controls beta-amyloid production by regulating macropinocytosis of the Amyloid Precursor Protein to lysosomes.
Weihao Tang, Joshua H K Tam, Claudia Seah, Justin Chiu, Andrea Tyrer, Susan O Meakin

Mol Brain· July 2015

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Imaging chemical exchange saturation transfer (CEST) effects following tumor-selective acidification using lonidamine.
Nevin McVicar, Alex X Li, Susan O Meakin, Robert Bartha

NMR Biomed· May 2015

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The signaling adapter, FRS2, facilitates neuronal branching in primary cortical neurons via both Grb2- and Shp2-dependent mechanisms.
Li Zhou, Asghar Talebian, Susan O Meakin

J Mol Neurosci· March 2015

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Quantitative tissue pH measurement during cerebral ischemia using amine and amide concentration-independent detection (AACID) with MRI.
Nevin McVicar, Alex X Li, Daniela F Gonçalves, Miranda Bellyou, Susan O Meakin

J Cereb Blood Flow Metab· April 2014

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Nerve growth factor receptor TrkA, a new receptor in insulin signaling pathway in PC12 cells.
Thangiah Geetha, Shraddha D Rege, Salome E Mathews, Susan O Meakin, Morris F White

J Biol Chem· August 2013

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Ras guanine nucleotide releasing factor 1 (RasGrf1) enhancement of Trk receptor-mediated neurite outgrowth requires activation of both H-Ras and Rac.
Asghar Talebian, Kim Robinson-Brookes, James I S MacDonald, Susan O Meakin

J Mol Neurosci· January 2013

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Nesca, a novel neuronal adapter protein, links the molecular motor kinesin with the pre-synaptic membrane protein, syntaxin-1, in hippocampal neurons.
James I S MacDonald, Alfonso Dietrich, Sarah Gamble, Todd Hryciw, Robert Ian Grant, Susan O Meakin

J Neurochem· June 2012

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Nerve growth factor activation of the TrkA receptor induces cell death, by macropinocytosis, in medulloblastoma Daoy cells.
Chunhui Li, James I S Macdonald, Todd Hryciw, Susan O Meakin

J Neurochem· February 2010

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The fibroblast growth factor receptor substrate 3 adapter is a developmentally regulated microtubule-associated protein expressed in migrating and differentiated neurons.
Todd Hryciw, James I S MacDonald, Renée Phillips, Claudia Seah, Stephen Pasternak, Susan O Meakin

J Neurochem· February 2010

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Trypanosome trans-sialidase mediates neuroprotection against oxidative stress, serum/glucose deprivation, and hypoxia-induced neurite retraction in Trk-expressing PC12 cells.
Alicja Woronowicz, Schammim Ray Amith, Vanessa W Davis, Preethi Jayanth, Kristof De Vusser, Susan O Meakin

Glycobiology· July 2007

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Trk receptor binding and neurotrophin/fibroblast growth factor (FGF)-dependent activation of the FGF receptor substrate (FRS)-3.
Scott J Dixon, James I S MacDonald, Kim N Robinson, Christopher J Kubu, Susan O Meakin

Biochim Biophys Acta· April 2006

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Nerve growth factor increases connexin43 phosphorylation and gap junctional intercellular communication.
Paul Cushing, Ruchi Bhalla, Andrew M Johnson, Walter J Rushlow, Susan O Meakin

J Neurosci Res· December 2005

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Human tumorous imaginal disc 1 (TID1) associates with Trk receptor tyrosine kinases and regulates neurite outgrowth in nnr5-TrkA cells.
Hui-Yu Liu, James I S MacDonald, Todd Hryciw, Chunhui Li, Susan O Meakin

J Biol Chem· May 2005

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Neurotrophin-dependent tyrosine phosphorylation of Ras guanine-releasing factor 1 and associated neurite outgrowth is dependent on the HIKE domain of TrkA.
Kim N Robinson, Kara Manto, Rachel J Buchsbaum, James I S MacDonald, Susan O Meakin

J Biol Chem· January 2005

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Trypanosome trans-sialidase targets TrkA tyrosine kinase receptor and induces receptor internalization and activation.
Alicja Woronowicz, Kristof De Vusser, Wouter Laroy, Roland Contreras, Susan O Meakin

Glycobiology· November 2004

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ShcA regulates neurite outgrowth stimulated by neural cell adhesion molecule but not by fibroblast growth factor 2: evidence for a distinct fibroblast growth factor receptor response to neural cell adhesion molecule activation.
Anders M Hinsby, Line Lundfald, Dorte K Ditlevsen, Irina Korshunova, Lone Juhl, Susan O Meakin

J Neurochem· November 2004

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Nesca, a novel adapter, translocates to the nuclear envelope and regulates neurotrophin-induced neurite outgrowth.
James I S MacDonald, Chris J Kubu, Susan O Meakin

J Cell Biol· March 2004

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Acidic substitution of the activation loop tyrosines in TrkA supports nerve growth factor-dependent, but not nerve growth factor-independent, differentiation and cell cycle arrest in the human neuroblastoma cell line, SY5Y.
Ela A Gryz, Susan O Meakin

Oncogene· November 2003

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Ectopic expression of the TrkA receptor in adult dopaminergic mesencephalic neurons promotes retrograde axonal NGF transport and NGF-dependent neuroprotection.
Benoît Melchior, Véronique Nerrière-Daguin, David A Laplaud, Séverine Rémy, Sandrine Wiertlewski, Susan O Meakin

Exp Neurol· October 2003

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The signaling adapters fibroblast growth factor receptor substrate 2 and 3 are activated by the thyroid TRK oncoproteins.
Valeria Ranzi, Susan O Meakin, Claudia Miranda, Piera Mondellini, Marco A Pierotti

Endocrinology· March 2003

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Genomic organization and comparative sequence analysis of the mouse and human FRS2, FRS3 genes.
Li Zhou, Kathryn McDougall, Christopher J Kubu, Joseph M Verdi, Susan O Meakin

Mol Biol Rep· March 2003

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Neutralizing intraspinal nerve growth factor with a trkA-IgG fusion protein blocks the development of autonomic dysreflexia in a clip-compression model of spinal cord injury.
Daniel R Marsh, Sharon T Wong, Susan O Meakin, James I S MacDonald, Eilis F Hamilton

J Neurotrauma· December 2002

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