Publications by authors named "Susan Shimmon"

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Novel Phenylene Lipids That Are Positive Allosteric Modulators of Glycine Receptors and Inhibitors of Glycine Transporter 2.
Casey I Gallagher, Zachary J Frangos, Diba Sheipouri, Susan Shimmon, Meryem-Nur Duman

ACS Chem Neurosci· August 2023

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Peripheral Administration of Selective Glycine Transporter-2 Inhibitor, Oleoyl--Lysine, Reverses Chronic Neuropathic Pain but Not Acute or Inflammatory Pain in Male Mice.
Bruce S Wilson, Julian Peiser-Oliver, Alexander Gillis, Sally Evans, Claudia Alamein, Susan Shimmon

J Pharmacol Exp Ther· September 2022

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The allosteric inhibition of glycine transporter 2 by bioactive lipid analgesics is controlled by penetration into a deep lipid cavity.
Katie A Wilson, Shannon N Mostyn, Zachary J Frangos, Susan Shimmon, Tristan Rawling

J Biol Chem· August 2021

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A System for Assessing Dual Action Modulators of Glycine Transporters and Glycine Receptors.
Diba Sheipouri, Casey I Gallagher, Susan Shimmon, Tristan Rawling, Robert J Vandenberg

Biomolecules· November 2020

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Identification of N-acyl amino acids that are positive allosteric modulators of glycine receptors.
Casey I Gallagher, Diba Sheipouri, Susan Shimmon, Tristan Rawling, Robert J Vandenberg

Biochem Pharmacol· October 2020

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Photoswitchable ORG25543 Congener Enables Optical Control of Glycine Transporter 2.
Shannon N Mostyn, Subhodeep Sarker, Parthasarathy Muthuraman, Arun Raja, Susan Shimmon

ACS Chem Neurosci· May 2020

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Identification of an allosteric binding site on the human glycine transporter, GlyT2, for bioactive lipid analgesics.
Shannon N Mostyn, Katie A Wilson, Alexandra Schumann-Gillett, Zachary J Frangos, Susan Shimmon

Elife· October 2019

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Development of an N-Acyl Amino Acid That Selectively Inhibits the Glycine Transporter 2 To Produce Analgesia in a Rat Model of Chronic Pain.
Shannon N Mostyn, Tristan Rawling, Sarasa Mohammadi, Susan Shimmon, Zachary J Frangos

J Med Chem· March 2019

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Pentosan polysulfate binds to STRO-1 mesenchymal progenitor cells, is internalized, and modifies gene expression: a novel approach of pre-programing stem cells for therapeutic application requiring their chondrogenesis.
Jiehua Wu, Susan Shimmon, Sharon Paton, Christopher Daly, Tony Goldschlager

Stem Cell Res Ther· December 2017

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Synthesis and Characterization of Novel Acyl-Glycine Inhibitors of GlyT2.
Shannon N Mostyn, Jane E Carland, Susan Shimmon, Renae M Ryan, Tristan Rawling

ACS Chem Neurosci· September 2017

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Remarkable thermal stability of gold nanoparticles functionalised with ruthenium phthalocyanine complexes.
Shirin R King, Susan Shimmon, Angus R Gentle, Mika T Westerhausen, Annette Dowd

Nanotechnology· May 2016

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Mesenchymal progenitor cells combined with pentosan polysulfate mediating disc regeneration at the time of microdiscectomy: a preliminary study in an ovine model.
David Oehme, Peter Ghosh, Susan Shimmon, Jiehua Wu, Courtney McDonald

J Neurosurg Spine· June 2014

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Pentosan polysulfate promotes proliferation and chondrogenic differentiation of adult human bone marrow-derived mesenchymal precursor cells.
Peter Ghosh, Jiehua Wu, Susan Shimmon, Andrew Cw Zannettino, Stan Gronthos

Arthritis Res Ther· August 2010

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Biosensor analysis of the molecular interactions of pentosan polysulfate and of sulfated glycosaminoglycans with immobilized elastase, hyaluronidase and lysozyme using surface plasmon resonance (SPR) technology.
Bojiang Shen, Susan Shimmon, Margaret M Smith, Peter Ghosh

J Pharm Biomed Anal· February 2003

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