Publications by authors named "Susan Tzotzos"

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The Epithelial Sodium Channel-An Underestimated Drug Target.
Rosa Lemmens-Gruber, Susan Tzotzos

Int J Mol Sci· April 2023

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Stapled peptides as potential inhibitors of SARS-CoV-2 binding to the hACE2 receptor.
Susan Tzotzos

J Pept Sci· September 2022

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Conformational ensemble of the TNF-derived peptide solnatide in solution.
Pau Martin-Malpartida, Silvia Arrastia-Casado, Josep Farrera-Sinfreu, Rudolf Lucas, Hendrik Fischer, Susan Tzotzos

Comput Struct Biotechnol J· April 2022

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Incidence of ARDS and outcomes in hospitalized patients with COVID-19: a global literature survey.
Susan J Tzotzos, Bernhard Fischer, Hendrik Fischer, Markus Zeitlinger

Crit Care· August 2020

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TNF Lectin-Like Domain Restores Epithelial Sodium Channel Function in Frameshift Mutants Associated with Pseudohypoaldosteronism Type 1B.
Anita Willam, Mohammed Aufy, Susan Tzotzos, Dina El-Malazi, Franziska Poser

Front Immunol· May 2017

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Restoration of Epithelial Sodium Channel Function by Synthetic Peptides in Pseudohypoaldosteronism Type 1B Mutants.
Anita Willam, Mohammed Aufy, Susan Tzotzos, Heinrich Evanzin, Sabine Chytracek

Front Pharmacol· February 2017

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The Lectin-like Domain of TNF Increases ENaC Open Probability through a Novel Site at the Interface between the Second Transmembrane and C-terminal Domains of the α-Subunit.
Rudolf Lucas, Qiang Yue, Abdel Alli, Billie Jeanne Duke, Otor Al-Khalili, Susan Tzotzos

J Biol Chem· November 2016

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Glycosylation-dependent activation of epithelial sodium channel by solnatide.
Waheed Shabbir, Susan Tzotzos, Minela Bedak, Mohammad Aufy, Anita Willam

Biochem Pharmacol· December 2015

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A FIM study to assess safety and exposure of inhaled single doses of AP301-A specific ENaC channel activator for the treatment of acute lung injury.
Richard Schwameis, Sandra Eder, Helmut Pietschmann, Bernhard Fischer, Hermann Mascher, Susan Tzotzos

J Clin Pharmacol· March 2014

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Mechanism of action of novel lung edema therapeutic AP301 by activation of the epithelial sodium channel.
Waheed Shabbir, Parastoo Scherbaum-Hazemi, Susan Tzotzos, Bernhard Fischer, Hendrik Fischer

Mol Pharmacol· December 2013

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AP301, a synthetic peptide mimicking the lectin-like domain of TNF, enhances amiloride-sensitive Na(+) current in primary dog, pig and rat alveolar type II cells.
Susan Tzotzos, Bernhard Fischer, Hendrik Fischer, Helmut Pietschmann, Rudolf Lucas

Pulm Pharmacol Ther· June 2013

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Essential structural features of TNF-α lectin-like domain derived peptides for activation of amiloride-sensitive sodium current in A549 cells.
Parastoo Hazemi, Susan J Tzotzos, Bernhard Fischer, Gowri Shankar Bagavananthem Andavan, Hendrik Fischer

J Med Chem· November 2010

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Amyloidogenic sequences in native protein structures.
Susan Tzotzos, Andrew J Doig

Protein Sci· February 2010

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Mechanisms of quinolone resistance in clinical isolates of Enterobacter cloacae.
Apostolos Georgopoulos, Robert Schein, Astrid Buxbaum, Susan Tzotzos, Alexander Hirschl

Clin Microbiol Infect· February 1998

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