Publications by authors named "Susana Proenca"

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Towards NAM-based risk assessment for developmental neurotoxic effects, illustrated with chlorpyrifos.
Anne Zwartsen, Joost Westerhout, Shensheng Zhao, Victoria C de Leeuw, Véronique M P de Bruijn

ALTEX· October 2025

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Comparison of physiologically based pharmacokinetic modeling platforms for developmental neurotoxicity in vitro to in vivo extrapolation.
Anna Kreutz, Xiaoqing Chang, Michael Lawless, Susana Proença, Stephan Schaller

Toxicol Sci· October 2025

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Harnessing Open-Source Solutions: Insights From the First Open Systems Pharmacology (OSP) Community Conference.
André Dallmann, Denise Feick, Pavel Balazki, Salih Benamara, Rolf Burghaus

CPT Pharmacometrics Syst Pharmacol· May 2025

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Integrating distribution kinetics and toxicodynamics to assess repeat dose neurotoxicity using human BrainSpheres: a case study on amiodarone.
Carolina Nunes, Susana Proença, Giovanna Ambrosini, David Pamies, Aurélien Thomas

Front Pharmacol· September 2023

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The effects of hexabromocyclododecane on the transcriptome and hepatic enzyme activity in three human HepaRG-based models.
Susana Proença, Nick van Sabben, Juliette Legler, Jorke H Kamstra, Nynke I Kramer

Toxicology· February 2023

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Drug Metabolism of Hepatocyte-like Organoids and Their Applicability in In Vitro Toxicity Testing.
Manon C Bouwmeester, Yu Tao, Susana Proença, Frank G van Steenbeek, Roos-Anne Samsom

Molecules· January 2023

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HiPSC-Derived Hepatocyte-like Cells Can Be Used as a Model for Transcriptomics-Based Study of Chemical Toxicity.
Sreya Ghosh, Jonathan De Smedt, Tine Tricot, Susana Proença, Manoj Kumar

Toxics· December 2021

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Effective exposure of chemicals in in vitro cell systems: A review of chemical distribution models.
Susana Proença, Beate I Escher, Fabian C Fischer, Ciarán Fisher, Sébastien Grégoire

Toxicol In Vitro· June 2021

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Insights into in vitro biokinetics using Virtual Cell Based Assay simulations.
Susana Proença, Alicia Paini, Elisabeth Joossens, Jose Vicente Sala Benito, Elisabet Berggren

ALTEX· January 2020

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Pyridine-Containing Macrocycles Display MMP-2/9 Inhibitory Activity and Distinct Effects on Migration and Invasion of 2D and 3D Breast Cancer Models.
Susana Proença, Bernardo Antunes, Rita C Guedes, Filipa Ramilo-Gomes, M Fátima Cabral

Int J Mol Sci· October 2019

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