Publications by authors named "Susann Matthes"

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Novel Tryptophan Hydroxylase Inhibitor TPT-001 Reverses PAH, Vascular Remodeling, and Proliferative-Proinflammatory Gene Expression.
Ekaterina Legchenko, Philippe Chouvarine, Fatimunnisa Qadri, Edgar Specker, Marc Nazaré, Susann Matthes

JACC Basic Transl Sci· July 2024

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Structure-Based Design of Xanthine-Imidazopyridines and -Imidazothiazoles as Highly Potent and In Vivo Efficacious Tryptophan Hydroxylase Inhibitors.
Edgar Specker, Radoslaw Wesolowski, Anja Schütz, Susann Matthes, Keven Mallow

J Med Chem· November 2023

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Structure-Based Design of Xanthine-Benzimidazole Derivatives as Novel and Potent Tryptophan Hydroxylase Inhibitors.
Edgar Specker, Susann Matthes, Radoslaw Wesolowski, Anja Schütz, Maik Grohmann

J Med Chem· August 2022

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Enduring Effects of Conditional Brain Serotonin Knockdown, Followed by Recovery, on Adult Rat Neurogenesis and Behavior.
Maria Sidorova, Golo Kronenberg, Susann Matthes, Markus Petermann, Rainer Hellweg

Cells· November 2021

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Community-Wide Experimental Evaluation of the PROSS Stability-Design Method.
Yoav Peleg, Renaud Vincentelli, Brett M Collins, Kai-En Chen, Emma K Livingstone, Susann Matthes

J Mol Biol· June 2021

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Phenylalanine hydroxylase contributes to serotonin synthesis in mice.
Alexander Mordhorst, Priyavathi Dhandapani, Susann Matthes, Valentina Mosienko, Michael Rothe

FASEB J· June 2021

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Targeted Manipulation of Brain Serotonin: RNAi-Mediated Knockdown of Tryptophan Hydroxylase 2 in Rats.
Susann Matthes, Valentina Mosienko, Elena Popova, Marion Rivalan, Michael Bader

ACS Chem Neurosci· July 2019

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Depletion of angiotensin-converting enzyme 2 reduces brain serotonin and impairs the running-induced neurogenic response.
Friederike Klempin, Valentina Mosienko, Susann Matthes, Daniel C Villela, Mihail Todiras

Cell Mol Life Sci· October 2018

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Peripheral Serotonin Synthesis as a New Drug Target.
Susann Matthes, Michael Bader

Trends Pharmacol Sci· June 2018

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Life without brain serotonin: reevaluation of serotonin function with mice deficient in brain serotonin synthesis.
Valentina Mosienko, Daniel Beis, Massimo Pasqualetti, Jonas Waider, Susann Matthes

Behav Brain Res· January 2015

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Reply to Lrp5 regulation of bone mass and gut serotonin synthesis.
Yajun Cui, Paul J Niziolek, Bryan T MacDonald, Natalia Alenina, Susann Matthes

Nat Med· November 2014

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Adaptive changes in serotonin metabolism preserve normal behavior in mice with reduced TPH2 activity.
Valentina Mosienko, Susann Matthes, Natalie Hirth, Daniel Beis, Michael Flinders

Neuropharmacology· October 2014

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Measurement of plasma, serum, and platelet serotonin in individuals with high bone mass and mutations in LRP5.
Grace S Lee, Christine Simpson, Ben-Hua Sun, Chen Yao, Dinah Foer, Susann Matthes

J Bone Miner Res· April 2014

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Lrp5 functions in bone to regulate bone mass.
Yajun Cui, Paul J Niziolek, Bryan T MacDonald, Cassandra R Zylstra, Natalia Alenina, Susann Matthes

Nat Med· June 2011

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Tryptophan hydroxylase as novel target for the treatment of depressive disorders.
Susann Matthes, Valentina Mosienko, Saleh Bashammakh, Natalia Alenina, Michael Bader

Pharmacology· October 2010

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