Publications by authors named "Suzanne M Scheaffer"

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Germinal center-mediated broadening of B cell responses to SARS-CoV-2 booster immunization.
Sameer Kumar Malladi, Deepika Jaiswal, Baoling Ying, Wafaa B Alsoussi, Tamarand L Darling, Suzanne M Scheaffer

Sci Immunol· October 2025

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A trivalent mucosal vaccine encoding phylogenetically inferred ancestral RBD sequences confers pan-Sarbecovirus protection in mice.
James Brett Case, Shilpa Sanapala, Carly Dillen, Victoria Rhodes, Christian Zmasek, Suzanne M Scheaffer

Cell Host Microbe· December 2024

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Defining a highly conserved B cell epitope in the receptor binding motif of SARS-CoV-2 spike glycoprotein.
Sameer Kumar Malladi, Deepika Jaiswal, Baoling Ying, Wafaa B Alsoussi, Tamarand L Darling, Suzanne M Scheaffer

bioRxiv· December 2024

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Ipsilateral or contralateral boosting of mice with mRNA vaccines confers equivalent immunity and protection against a SARS-CoV-2 Omicron strain.
Baoling Ying, Chieh-Yu Liang, Pritesh Desai, Suzanne M Scheaffer, Sayda M Elbashir

J Virol· September 2024

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Infiltrating monocytes drive cardiac dysfunction in a cardiomyocyte-restricted mouse model of SARS-CoV-2 infection.
Oleksandr Dmytrenko, Shibali Das, Attila Kovacs, Markus Cicka, Meizi Liu, Suzanne M Scheaffer

J Virol· September 2024

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Imprinting of serum neutralizing antibodies by Wuhan-1 mRNA vaccines.
Chieh-Yu Liang, Saravanan Raju, Zhuoming Liu, Yuhao Li, Guha Asthagiri Arunkumar, Suzanne M Scheaffer

Nature· June 2024

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Computationally restoring the potency of a clinical antibody against Omicron.
Thomas A Desautels, Kathryn T Arrildt, Adam T Zemla, Edmond Y Lau, Fangqiang Zhu, Suzanne M Scheaffer

Nature· May 2024

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Prototype and BA.5 protein nanoparticle vaccines protect against Omicron BA.5 variant in Syrian hamsters.
Traci L Bricker, Astha Joshi, Nadia Soudani, Suzanne M Scheaffer, Nita Patel

J Virol· March 2024

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Immunoglobulin replacement products protect against SARS-CoV-2 infection in vivo despite poor neutralizing activity.
Ofer Zimmerman, Alexa Michelle Altman Doss, Baoling Ying, Chieh-Yu Liang, Samantha R Mackin, Suzanne M Scheaffer

JCI Insight· February 2024

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Neutralization, effector function and immune imprinting of Omicron variants.
Amin Addetia, Luca Piccoli, James Brett Case, Young-Jun Park, Martina Beltramello, Suzanne M Scheaffer

Nature· September 2023

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Characterization of the SARS-CoV-2 BA.5.5 and BQ.1.1 Omicron variants in mice and hamsters.
James Brett Case, Suzanne M Scheaffer, Tamarand L Darling, Traci L Bricker, Lucas J Adams

J Virol· September 2023

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Domain-based mRNA vaccines encoding spike protein N-terminal and receptor binding domains confer protection against SARS-CoV-2.
Guillaume B E Stewart-Jones, Sayda M Elbashir, Kai Wu, Diana Lee, Isabella Renzi, Suzanne M Scheaffer

Sci Transl Med· September 2023

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SARS-CoV-2 Omicron boosting induces de novo B cell response in humans.
Wafaa B Alsoussi, Sameer Kumar Malladi, Julian Q Zhou, Zhuoming Liu, Baoling Ying, Suzanne M Scheaffer

Nature· May 2023

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Characterization of the SARS-CoV-2 BA.5.5 and BQ.1.1 Omicron Variants in Mice and Hamsters.
James Brett Case, Suzanne M Scheaffer, Tamarand L Darling, Traci L Bricker, Lucas J Adams

bioRxiv· May 2023

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Computationally restoring the potency of a clinical antibody against SARS-CoV-2 Omicron subvariants.
Thomas A Desautels, Kathryn T Arrildt, Adam T Zemla, Edmond Y Lau, Fangqiang Zhu, Suzanne M Scheaffer

bioRxiv· April 2023

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Persons with HIV Develop Spike-Specific Lymph Node Germinal Center Responses following SARS-CoV-2 Vaccination.
Michael Quinn, Luis Parra-Rodriguez, Wafaa B Alsoussi, Chapelle Ayres, Michael K Klebert, Suzanne M Scheaffer

J Immunol· April 2023

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Bivalent SARS-CoV-2 mRNA vaccines increase breadth of neutralization and protect against the BA.5 Omicron variant in mice.
Suzanne M Scheaffer, Diana Lee, Bradley Whitener, Baoling Ying, Kai Wu

Nat Med· January 2023

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Development of SARS-CoV-2 mRNA vaccines encoding spike N-terminal and receptor binding domains.
Guillaume B E Stewart-Jones, Sayda M Elbashir, Kai Wu, Diana Lee, Isabella Renzi, Suzanne M Scheaffer

bioRxiv· October 2022

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IMM-BCP-01, a patient-derived anti-SARS-CoV-2 antibody cocktail, is active across variants of concern including Omicron BA.1 and BA.2.
Pavel A Nikitin, Jillian M DiMuzio, John P Dowling, Nirja B Patel, Jamie L Bingaman-Steele, Suzanne M Scheaffer

Sci Immunol· September 2022

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SARS-CoV-2 Omicron boosting induces de novo B cell response in humans.
Wafaa B Alsoussi, Sameer K Malladi, Julian Q Zhou, Zhuoming Liu, Baoling Ying, Suzanne M Scheaffer

bioRxiv· September 2022

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Bivalent SARS-CoV-2 mRNA vaccines increase breadth of neutralization and protect against the BA.5 Omicron variant.
Suzanne M Scheaffer, Diana Lee, Bradley Whitener, Baoling Ying, Kai Wu

bioRxiv· September 2022

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Human induced pluripotent stem cell engineering establishes a humanized mouse platform for pediatric low-grade glioma modeling.
Corina Anastasaki, Jit Chatterjee, Olivia Cobb, Shilpa Sanapala, Suzanne M Scheaffer

Acta Neuropathol Commun· August 2022

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Neuronal hyperexcitability drives central and peripheral nervous system tumor progression in models of neurofibromatosis-1.
Corina Anastasaki, Juan Mo, Ji-Kang Chen, Jit Chatterjee, Yuan Pan, Suzanne M Scheaffer

Nat Commun· May 2022

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Boosting with variant-matched or historical mRNA vaccines protects against Omicron infection in mice.
Baoling Ying, Suzanne M Scheaffer, Bradley Whitener, Chieh-Yu Liang, Oleksandr Dmytrenko

Cell· April 2022

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Boosting with Omicron-matched or historical mRNA vaccines increases neutralizing antibody responses and protection against B.1.1.529 infection in mice.
Baoling Ying, Suzanne M Scheaffer, Bradley Whitener, Chieh-Yu Liang, Oleksandr Dmytrenko

bioRxiv· February 2022

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