Publications by authors named "Syd Barthorpe"

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High TNF and NF-κB Pathway Dependency Are Associated with AZD5582 Sensitivity in OSCC via CASP8-Dependent Apoptosis.
Annie Wai Yeeng Chai, Yee Hua Tan, Shiyin Ooi, Pei San Yee, Shi Mun Yee, Syd Barthorpe

Cancer Res Commun· November 2024

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Novel WRN Helicase Inhibitors Selectively Target Microsatellite-Unstable Cancer Cells.
Gabriele Picco, Yanhua Rao, Angham Al Saedi, Yang Lee, Sara F Vieira, Syd Barthorpe

Cancer Discov· August 2024

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A pan-cancer screen identifies drug combination benefit in cancer cell lines at the individual and population level.
Daniel J Vis, Patricia Jaaks, Nanne Aben, Elizabeth A Coker, Syd Barthorpe

Cell Rep Med· August 2024

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Large-scale Pan-cancer Cell Line Screening Identifies Actionable and Effective Drug Combinations.
Azadeh C Bashi, Elizabeth A Coker, Krishna C Bulusu, Patricia Jaaks, Claire Crafter, Syd Barthorpe

Cancer Discov· May 2024

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Establishment and Characterization of an Epstein-Barr Virus-positive Cell Line from a Non-keratinizing Differentiated Primary Nasopharyngeal Carcinoma.
Annie Wai Yeeng Chai, Shi Mun Yee, Hui Mei Lee, Norazlin Abdul Aziz, Pei San Yee, Syd Barthorpe

Cancer Res Commun· March 2024

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Base editing screens map mutations affecting interferon-γ signaling in cancer.
Matthew A Coelho, Sarah Cooper, Magdalena E Strauss, Emre Karakoc, Shriram Bhosle, Syd Barthorpe

Cancer Cell· February 2023

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Pan-cancer proteomic map of 949 human cell lines.
Emanuel Gonçalves, Rebecca C Poulos, Zhaoxiang Cai, Syd Barthorpe, Srikanth S Manda

Cancer Cell· August 2022

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Functional Genomic Identification of Predictors of Sensitivity and Mechanisms of Resistance to Multivalent Second-Generation TRAIL-R2 Agonists.
Vera Grinkevitch, Mark Wappett, Nyree Crawford, Stacey Price, Andrea Lees, Syd Barthorpe

Mol Cancer Ther· April 2022

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A suspension technique for efficient large-scale cancer organoid culturing and perturbation screens.
Stacey Price, Shriram Bhosle, Emanuel Gonçalves, Xiaodun Li, Dylan P McClurg, Syd Barthorpe

Sci Rep· April 2022

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Effective drug combinations in breast, colon and pancreatic cancer cells.
Patricia Jaaks, Elizabeth A Coker, Daniel J Vis, Olivia Edwards, Emma F Carpenter, Syd Barthorpe

Nature· March 2022

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Cell Model Passports-a hub for clinical, genetic and functional datasets of preclinical cancer models.
Dieudonne van der Meer, Syd Barthorpe, Wanjuan Yang, Howard Lightfoot, Caitlin Hall

Nucleic Acids Res· January 2019

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The Origins and Vulnerabilities of Two Transmissible Cancers in Tasmanian Devils.
Maximilian R Stammnitz, Tim H H Coorens, Kevin C Gori, Dane Hayes, Beiyuan Fu, Syd Barthorpe

Cancer Cell· April 2018

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Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells.
Krishna Kalyan Kolluri, Constantine Alifrangis, Neelam Kumar, Yuki Ishii, Stacey Price, Syd Barthorpe

Elife· January 2018

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Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations.
Jonathan S Brammeld, Mia Petljak, Inigo Martincorena, Steven P Williams, Luz Garcia Alonso, Syd Barthorpe

Genome Res· April 2017

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A Landscape of Pharmacogenomic Interactions in Cancer.
Francesco Iorio, Theo A Knijnenburg, Daniel J Vis, Graham R Bignell, Michael P Menden, Syd Barthorpe

Cell· July 2016

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Combinations of PARP Inhibitors with Temozolomide Drive PARP1 Trapping and Apoptosis in Ewing's Sarcoma.
Sonja J Gill, Jon Travers, Irina Pshenichnaya, Fiona A Kogera, Syd Barthorpe

PLoS One· June 2016

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Systematic identification of genomic markers of drug sensitivity in cancer cells.
Mathew J Garnett, Elena J Edelman, Sonja J Heidorn, Chris D Greenman, Anahita Dastur, Syd Barthorpe

Nature· March 2012

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Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes.
Gillian L Dalgliesh, Kyle Furge, Chris Greenman, Lina Chen, Graham Bignell, Syd Barthorpe

Nature· January 2010

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Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer.
Gijs van Haaften, Gillian L Dalgliesh, Helen Davies, Lina Chen, Graham Bignell, Syd Barthorpe

Nat Genet· May 2009

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A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation.
Patrick S Tarpey, Raffaella Smith, Erin Pleasance, Annabel Whibley, Sarah Edkins, Syd Barthorpe

Nat Genet· May 2009

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X-linked protocadherin 19 mutations cause female-limited epilepsy and cognitive impairment.
Leanne M Dibbens, Patrick S Tarpey, Kim Hynes, Marta A Bayly, Ingrid E Scheffer, Syd Barthorpe

Nat Genet· June 2008

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Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardation.
Patrick S Tarpey, F Lucy Raymond, Lam S Nguyen, Jayson Rodriguez, Anna Hackett, Syd Barthorpe

Nat Genet· September 2007

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Mutations in the BRWD3 gene cause X-linked mental retardation associated with macrocephaly.
Michael Field, Patrick S Tarpey, Raffaella Smith, Sarah Edkins, Sarah O'Meara, Syd Barthorpe

Am J Hum Genet· August 2007

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Mutations in ZDHHC9, which encodes a palmitoyltransferase of NRAS and HRAS, cause X-linked mental retardation associated with a Marfanoid habitus.
F Lucy Raymond, Patrick S Tarpey, Sarah Edkins, Calli Tofts, Sarah O'Meara, Syd Barthorpe

Am J Hum Genet· May 2007

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Patterns of somatic mutation in human cancer genomes.
Christopher Greenman, Philip Stephens, Raffaella Smith, Gillian L Dalgliesh, Christopher Hunter, Syd Barthorpe

Nature· March 2007

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