Publications by authors named "Tackhoon Kim"

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Perturbomics: CRISPR-Cas screening-based functional genomics approach for drug target discovery.
Byung-Sun Park, Mieun Lee, Jaeyeol Kim, Tackhoon Kim

Exp Mol Med· July 2025

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Combinatorial CRISPR screen reveals and as targets for synergistic drug combination for treating triple negative breast cancer.
Tackhoon Kim, Byung-Sun Park, Soobeen Heo, Heeju Jeon, Jaeyeal Kim, Donghwa Kim

Elife· April 2025

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Polyamine and EIF5A hypusination downstream of c-Myc confers targeted therapy resistance in BRAF mutant melanoma.
Byung-Sun Park, Heeju Jeon, Yeonseo Kim, Haejin Kwon, Ga-Eun Choi, Tackhoon Kim

Mol Cancer· July 2024

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Discovery of dioxo-benzo[b]thiophene derivatives as potent YAP-TEAD interaction inhibitors for treating breast cancer.
Youngchai Son, Jaeyeal Kim, Yongchan Kim, Sung-Gil Chi, Tackhoon Kim

Bioorg Chem· February 2023

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Efficient prioritization of CRISPR screen hits by accounting for targeting efficiency of guide RNA.
Byung-Sun Park, Heeju Jeon, Sung-Gil Chi, Tackhoon Kim

BMC Biol· February 2023

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Scalable recombinase-based gene expression cascades.
Tackhoon Kim, Benjamin Weinberg, Wilson Wong, Timothy K Lu

Nat Commun· May 2021

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CRISPR/Cas-based devices for mammalian synthetic biology.
Tackhoon Kim, Timothy K Lu

Curr Opin Chem Biol· October 2019

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Mechanical cue-induced YAP instructs Skp2-dependent cell cycle exit and oncogenic signaling.
Wonyul Jang, Tackhoon Kim, Ja Seung Koo, Sang-Kyum Kim, Dae-Sik Lim

EMBO J· September 2017

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The novel YAP target gene, SGK1, upregulates TAZ activity by blocking GSK3β-mediated TAZ destabilization.
Geon Yoo, Tackhoon Kim, Chaeuk Chung, Deog-Su Hwang, Dae-Sik Lim

Biochem Biophys Res Commun· August 2017

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Prostaglandin E Activates YAP and a Positive-Signaling Loop to Promote Colon Regeneration After Colitis but Also Carcinogenesis in Mice.
Han-Byul Kim, Minchul Kim, Young-Soo Park, Intae Park, Tackhoon Kim

Gastroenterology· February 2017

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MRTF potentiates TEAD-YAP transcriptional activity causing metastasis.
Tackhoon Kim, Daehee Hwang, Dahye Lee, Jeong-Hwan Kim, Seon-Young Kim

EMBO J· February 2017

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The E3 ubiquitin ligase CHIP selectively regulates mutant epidermal growth factor receptor by ubiquitination and degradation.
Chaeuk Chung, Geon Yoo, Tackhoon Kim, Dahye Lee, Choong-Sik Lee, Ju Ock Kim, Sun Young Kim

Biochem Biophys Res Commun· October 2016

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LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression during liver development.
Da-Hye Lee, Jae Oh Park, Tae-Shin Kim, Sang-Kyum Kim, Tack-Hoon Kim, Min-Chul Kim, Jeong-Hwan Kim, Seon-Young Kim

Nat Commun· June 2016

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Hippo pathway effector YAP inhibition restores the sensitivity of EGFR-TKI in lung adenocarcinoma having primary or acquired EGFR-TKI resistance.
Jeong Eun Lee, Hee Sun Park, Dahye Lee, Geon Yoo, Tackhoon Kim, Ju Ock Kim, Sun Young Kim

Biochem Biophys Res Commun· May 2016

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The SRF-YAP-IL6 axis promotes breast cancer stemness.
Tackhoon Kim, Dae-Sik Lim

Cell Cycle· May 2016

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An evolutionarily conserved negative feedback mechanism in the Hippo pathway reflects functional difference between LATS1 and LATS2.
Gun-Soo Park, Hyangyee Oh, Minchul Kim, Tackhoon Kim, Randy L Johnson

Oncotarget· April 2016

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A basal-like breast cancer-specific role for SRF-IL6 in YAP-induced cancer stemness.
Tackhoon Kim, Suk-Jin Yang, Daehee Hwang, Jinhoi Song, Minchul Kim, Sang Kyum Kim, Mi-Young Kim, Seyun Kim, Seon-Young Kim

Nat Commun· December 2015

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Trunk and pelvic coordination at various walking speeds during an anterior load carriage task in subjects with and without chronic low back pain.
Tackhoon Kim, Eunsu Chai

J Phys Ther Sci· July 2015

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Reversing the intractable nature of pancreatic cancer by selectively targeting ALDH-high, therapy-resistant cancer cells.
Sang Kyum Kim, Honsoul Kim, Da-Hye Lee, Tae-shin Kim, Tackhoon Kim, Hoguen Kim

PLoS One· February 2015

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Effects of vojta therapy on gait of children with spastic diplegia.
Hyungwon Lim, Tackhoon Kim

J Phys Ther Sci· December 2013

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Real-time single-molecule co-immunoprecipitation analyses reveal cancer-specific Ras signalling dynamics.
Hong-Won Lee, Taeyoon Kyung, Janghyun Yoo, Tackhoon Kim, Chaeuk Chung

Nat Commun· June 2013

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Hippo-Foxa2 signaling pathway plays a role in peripheral lung maturation and surfactant homeostasis.
Chaeuk Chung, Tackhoon Kim, Miju Kim, Minchul Kim, Hoogeun Song, Tae-Shin Kim, Hanbyul Kim, Sang Kyum Kim, Jin-Man Kim

Proc Natl Acad Sci U S A· May 2013

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The Er71 is an important regulator of hematopoietic stem cells in adult mice.
Dongjun Lee, Tackhoon Kim, Dae-Sik Lim

Stem Cells· March 2011

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The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis.
Kwang-Pyo Lee, Joo-Hyeon Lee, Tae-Shin Kim, Tack-Hoon Kim, Hee-Dong Park, Min-Chul Kim, Jin-Man Kim

Proc Natl Acad Sci U S A· May 2010

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MST1 limits the kinase activity of aurora B to promote stable kinetochore-microtubule attachment.
Hyun Jung Oh, Mi Ju Kim, Su Jung Song, Tackhoon Kim, Dongjun Lee

Curr Biol· March 2010

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