Publications by authors named "Taizo Uda"

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Structural and biochemical differences between non-catalytic and catalytic antibodies.
Taizo Uda, Ryuichi Kato, Yasuteru Shigeta, Shun Hirota, Jun Kobayashi

MAbs· December 2025

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Experimental and Computational Studies on Domain-Swapped Structure Stabilization of an Antibody Light Chain by Disulfide Bond Introduction.
Wahyu Fitriana, Takahiro Sakai, Lian Duan, Kowit Hengphasatporn, Yasuteru Shigeta, Taizo Uda

J Med Chem· December 2024

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E
Enzymatization of mouse monoclonal antibodies to the corresponding catalytic antibodies.
Emi Hifumi, Yuina Ito, Moe Tsujita, Hiroaki Taguchi, Taizo Uda

Sci Rep· May 2024

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Structural and thermodynamic insights into antibody light chain tetramer formation through 3D domain swapping.
Takahiro Sakai, Tsuyoshi Mashima, Naoya Kobayashi, Hideaki Ogata, Lian Duan, Taizo Uda

Nat Commun· December 2023

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Direct conversion of a general antibody to its catalytic antibody and corresponding applications -Importance and role of Pro95 in CDR-3.
Emi Hifumi, Hiroaki Taguchi, Tamami Nonaka, Taizo Uda

Proc Jpn Acad Ser B Phys Biol Sci· June 2023

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A new catalytic site functioning in antigen cleavage by H34 catalytic antibody light chain.
Emi Hifumi, Tamami Nonaka, Hiroaki Taguchi, Taizo Uda

Sci Rep· November 2022

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Obtaining Highly Active Catalytic Antibodies Capable of Enzymatically Cleaving Antigens.
Tamami Nonaka, Hiroaki Taguchi, Taizo Uda, Emi Hifumi

Int J Mol Sci· November 2022

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Finding and characterizing a catalytic antibody light chain, H34, capable of degrading the PD-1 molecule.
Emi Hifumi, Hiroaki Taguchi, Tamami Nonaka, Takunori Harada, Taizo Uda

RSC Chem Biol· February 2021

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A new algorithm to convert a normal antibody into the corresponding catalytic antibody.
Emi Hifumi, Hiroaki Taguchi, Haruna Tsuda, Tetsuro Minagawa, Tamami Nonaka, Taizo Uda

Sci Adv· March 2020

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New technologies to introduce a catalytic function into antibodies: A unique human catalytic antibody light chain showing degradation of β-amyloid molecule along with the peptidase activity.
Emi Hifumi, Hiroaki Taguchi, Eiichi Toorisaka, Taizo Uda

FASEB Bioadv· February 2019

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Role of the constant region domain in the structural diversity of human antibody light chains.
Emi Hifumi, Hiroaki Taguchi, Ryuichi Kato, Taizo Uda

FASEB J· April 2017

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A novel method of preparing the monoform structure of catalytic antibody light chain.
Emi Hifumi, Shingo Matsumoto, Hiroki Nakashima, Shogo Itonaga, Mitsue Arakawa, Taizo Uda

FASEB J· February 2016

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Biochemical features and antiviral activity of a monomeric catalytic antibody light-chain 23D4 against influenza A virus.
Emi Hifumi, Mitsue Arakawa, Shingo Matsumoto, Tatsuhiro Yamamoto, Yoshiki Katayama, Taizo Uda

FASEB J· June 2015

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Biochemical features of a catalytic antibody light chain, 22F6, prepared from human lymphocytes.
Emi Hifumi, Naoko Fujimoto, Mitsue Arakawa, Eri Saito, Shingo Matsumoto, Taizo Uda

J Biol Chem· July 2013

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Highly efficient method of preparing human catalytic antibody light chains and their biological characteristics.
Emi Hifumi, Eijiro Honjo, Naoko Fujimoto, Mitsue Arakawa, Akira Nishizono, Taizo Uda

FASEB J· April 2012

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C
Catalytic and biochemical features of a monoclonal antibody heavy chain, JN1-2, raised against a synthetic peptide with a hemagglutinin molecule of influenza virus.
Emi Hifumi, Shin-Ichi Takao, Naoko Fujimoto, Taizo Uda

J Am Chem Soc· September 2011

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Catalytic digestion of human tumor necrosis factor-α by antibody heavy chain.
Emi Hifumi, Kyohei Higashi, Taizo Uda

FEBS J· September 2010

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A flow-through electrochemiluminescence sensor for salt stress on rice plants.
Naoyoshi Egashira, Tsuyoshi Yamamoto, Tomio Itani, Yoshiharu Mitoma, Taizo Uda

Anal Sci· June 2010

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Characteristic features of InfA-15 monoclonal antibody recognizing H1, H3, and H5 subtypes of hemagglutinin of influenza virus A type.
Emi Hifumi, Naoko Fujimoto, Kazuya Ishida, Hirokazu Kawawaki, Taizo Uda

J Biosci Bioeng· June 2010

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Varied immune response to FVIII: presence of proteolytic antibodies directed to factor VIII in different human pathologies.
Bharath Wootla, Desirazu Narasimha Rao, Alain Friboulet, Taizo Uda, Sébastien Lacroix-Desmazes

Clin Rev Allergy Immunol· October 2009

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Factor VIII-hydrolyzing IgG in acquired and congenital hemophilia.
Bharath Wootla, Ankit Mahendra, Jordan D Dimitrov, Alain Friboulet, Annie Borel-Derlon, Taizo Uda

FEBS Lett· August 2009

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Therapeutic effects of molecularly designed antigen UREB138 for mice infected with Helicobacter pylori.
Fumiko Morihara, Emi Hifumi, Manabu Yamada, Akira Nishizono, Taizo Uda

Biotechnol Bioeng· July 2008

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Attomole detection of hemagglutinin molecule of influenza virus by combining an electrochemiluminescence sensor with an immunoliposome that encapsulates a Ru complex.
Naoyoshi Egashira, Shin-ichi Morita, Emi Hifumi, Yoshiharu Mitoma, Taizo Uda

Anal Chem· June 2008

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Catalytic features and eradication ability of antibody light-chain UA15-L against Helicobacter pylori.
Emi Hifumi, Fumiko Morihara, Kenji Hatiuchi, Takuro Okuda, Akira Nishizono, Taizo Uda

J Biol Chem· January 2008

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Effects of vaccination by a recombinant antigen ureB138 (a segment of the beta-subunit of urease) against Helicobacter pylori infection.
Fumiko Morihara, Ryoji Fujii, Emi Hifumi, Akira Nishizono, Taizo Uda

J Med Microbiol· June 2007

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