Publications by authors named "Takehiro Tozuka"

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ACTN4 Gene Amplification and Actinin-4 Protein Expression for Osimertinib Efficacy in EGFR-Mutant NSCLC.
Takehiro Tozuka, Rintaro Noro, Yutaka Naito, Nami Miura, Shinobu Kunugi

Cancer Sci· December 2025

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Lung immune prognostic index as a biomarker for predicting the benefit of immune checkpoint inhibitor plus chemotherapy in older patients with non-small cell lung cancer: a secondary analysis of the NEJ057 study.
Takehiro Tozuka, Yoko Tsukita, Kohei Kushiro, Shinobu Hosokawa, Hitomi Nogawa

Int J Clin Oncol· December 2025

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Phase II Study of Short Hydration without Diuretics for Cisplatin-Based Chemotherapy.
Tetsuya Wako, Ryosuke Arakawa, Shinji Nakamichi, Masaru Matsumoto, Rei Yamaguchi, Takehiro Tozuka

J Nippon Med Sch· May 2025

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Efficacy and safety of pleurodesis for lung cancer patients with interstitial lung disease.
Hirokazu Iso, Akihiko Miyanaga, Yozo Sato, Yukari Shirakura, Kaoruko Shinbu, Takehiro Tozuka

J Thorac Dis· February 2025

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Chemoimmunotherapy in Older Adults With Non-Small Cell Lung Cancer-Reply.
Hajime Asahina, Yoko Tsukita, Takehiro Tozuka

JAMA Oncol· December 2024

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Comparison of immune checkpoint inhibitor plus chemotherapy or ipilimumab plus nivolumab-based therapy for NSCLC patients with PD-L1 TPS (1-49 %): TOPGAN2023-01.
Hisashi Tanaka, Tomonori Makiguchi, Takehiro Tozuka, Yosuke Kawashima, Tomohiro Oba

Eur J Cancer· December 2024

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Ivermectin Enhances Paclitaxel Efficacy by Overcoming Resistance Through Modulation of in Non-small Cell Lung Cancer.
Anna Hayashi, Koichiro Kamio, Akihiko Miyanaga, Keisuke Yoshida, Rintaro Noro, Takehiro Tozuka

Anticancer Res· December 2024

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Induction of resistance to neurotrophic tropomyosin-receptor kinase inhibitors by HMGCS2 via a mevalonate pathway.
Yasuhiro Kato, Masaru Matsumoto, Natsuki Takano, Mariko Hirao, Kuniko Matsuda, Takehiro Tozuka

Cancer Med· June 2024

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Osimertinib plus local treatment for brain metastases versus osimertinib alone in patients with EGFR-Mutant Non-Small Cell Lung Cancer.
Takehiro Tozuka, Rintaro Noro, Hideaki Mizutani, Futoshi Kurimoto, Taiki Hakozaki

Lung Cancer· May 2024

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Immunotherapy or Chemoimmunotherapy in Older Adults With Advanced Non-Small Cell Lung Cancer.
Yoko Tsukita, Takehiro Tozuka, Kohei Kushiro, Shinobu Hosokawa, Toshiyuki Sumi

JAMA Oncol· April 2024

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Phosphoproteomic Analysis Identified Mutual Phosphorylation of FAK and Src as a Mechanism of Osimertinib Resistance in -Mutant Lung Cancer.
Takehiro Tozuka, Rintaro Noro, Keisuke Yoshida, Satoshi Takahashi, Mariko Hirao

JTO Clin Res Rep· April 2024

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Immunotherapy With Radiotherapy for Brain Metastases in Patients With NSCLC: NEJ060.
Takehiro Tozuka, Yuji Minegishi, Ou Yamaguchi, Kana Watanabe, Yukihiro Toi

JTO Clin Res Rep· April 2024

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Second-line immunosuppressant administration for steroid-refractory immune-related adverse events in patients with lung cancer.
Shinsuke Ogusu, Yuhei Harutani, Takehiro Tozuka, Ryota Saito, Junji Koyama

Cancer Immunol Immunother· November 2023

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Successful Treatment with Definitive Concurrent Chemoradiotherapy Followed by Durvalumab Maintenance Therapy in a Patient with Tracheal Adenoid Cystic Carcinoma.
Erika Mikami, Shinji Nakamichi, Atsuhiro Nagano, Kazuhito Misawa, Anna Hayashi, Takehiro Tozuka

Intern Med· September 2023

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Osimertinib early dose reduction as a risk to brain metastasis control in EGFR-mutant non-small cell lung cancer.
Takehiro Tozuka, Rintaro Noro, Akihiko Miyanaga, Shinji Nakamichi, Susumu Takeuchi

Cancer Med· September 2023

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Subsequent treatment for locally advanced non-small-cell lung cancer that progressed after definitive chemoradiotherapy and consolidation therapy with durvalumab: a multicenter retrospective analysis (TOPGAN 2021-02).
Tsukasa Hasegawa, Ryo Ariyasu, Hisashi Tanaka, Ryota Saito, Yosuke Kawashima, Takehiro Tozuka

Cancer Chemother Pharmacol· July 2023

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Platinum-combination chemotherapy with or without immune-checkpoint inhibitor in patients with postoperative recurrent non-small cell lung cancer previously treated with adjuvant platinum-doublet chemotherapy: A multicenter retrospective study.
Kakeru Hisakane, Takehiro Tozuka, Satoshi Takahashi, Namiko Taniuchi, Nobuhiko Nishijima

Thorac Cancer· July 2023

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Soluble interleukin-2 receptor as a predictive biomarker for poor efficacy of combination treatment with anti-PD-1/PD-L1 antibodies and chemotherapy in non-small cell lung cancer patients.
Takehiro Tozuka, Noriko Yanagitani, Hiroshi Yoshida, Ryo Manabe, Shinsuke Ogusu

Invest New Drugs· June 2023

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Remarkable Clinical Response of -Rearranged/-Mutant Lung Adenocarcinoma with Liver Metastasis to Atezolizumab-Bevacizumab-Carboplatin-Paclitaxel After ALK Inhibitors: A Case Report.
Hirokazu Iso, Akihiko Miyanaga, Naohiro Kadoma, Kaoruko Shinbu, Takehiro Tozuka

Onco Targets Ther· June 2023

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Clinical efficacy of amrubicin in patients with small cell lung cancer relapse after first-line treatment including immune checkpoint inhibitors: A retrospective multicenter study (TOPGAN 2021-01).
Shinya Uematsu, Satoru Kitazono, Hisashi Tanaka, Ryota Saito, Yosuke Kawashima, Takehiro Tozuka

Thorac Cancer· January 2023

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Alectinib-Induced Severe Hemolytic Anemia in a Patient with ALK-Positive Non-Small Cell Lung Cancer: A Case Report.
Kazuhito Misawa, Shinji Nakamichi, Hiroki Iida, Atsuhiro Nagano, Erika Mikami, Takehiro Tozuka

Onco Targets Ther· January 2023

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Benefits from Adjuvant Chemotherapy in Patients with Resected Non-Small Cell Lung Cancer: Possibility of Stratification by Gene Amplification of According to Evaluation of Metastatic Ability.
Takehiro Tozuka, Rintaro Noro, Masahiro Seike, Kazufumi Honda

Cancers (Basel)· September 2022

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Successful Treatment with Short-Term Steroid Against Severe Hepatitis Confirmed by Liver Biopsy in a Patient with Advanced Squamous-Cell Lung Cancer Receiving a Combination of Pembrolizumab, Carboplatin, and Nab-Paclitaxel: A Case Report.
Anna Hayashi, Shinji Nakamichi, Yukako Nakayama, Atsuhiro Nagano, Erika Mikami, Takehiro Tozuka

Onco Targets Ther· June 2022

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Acute respiratory failure due to infection with acute fibrinous and organazing pneumonia: A case report.
Ken Okamura, Rintaro Noro, Kazue Fujita, Shoko Kure, Shinobu Kunugi, Takehiro Tozuka

Respir Med Case Rep· March 2022

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Characteristics of central nervous system progression in non-small cell lung cancer treated with crizotinib or alectinib.
Hiroaki Sakamoto, Noriko Yanagitani, Ryo Manabe, Ryosuke Tsugitomi, Shinsuke Ogusu, Takehiro Tozuka

Cancer Rep (Hoboken)· December 2021

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