Publications by authors named "Takuma Mihara"

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Monoclonal humanized monovalent antibody blocking therapy for anti-NMDA receptor encephalitis.
Atsuo Kanno, Takuya Kito, Masashi Maeda, Shanni Yamaki, Yasushi Amano, Takuma Mihara

Nat Commun· June 2025

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Chronic subdural electrocorticography in nonhuman primates by an implantable wireless device for brain-machine interfaces.
Tianfang Yan, Katsuyoshi Suzuki, Seiji Kameda, Masashi Maeda, Takuma Mihara

Front Neurosci· September 2023

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Suppressive effects of ketamine on auditory steady-state responses in intact, awake macaques: A non-human primate model of schizophrenia.
Tomoya Nakamura, Trong Ha Dinh, Makoto Asai, Jumpei Matsumoto, Hiroshi Nishimaru, Takuma Mihara

Brain Res Bull· February 2023

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Calcium/calmodulin-dependent protein kinase IIα heterozygous knockout mice show electroencephalogram and behavioral changes characteristic of a subpopulation of schizophrenia and intellectual impairment.
Robert E Featherstone, Takeshi Shimada, Lindsey M Crown, Olya Melnychenko, Janice Yi, Takuma Mihara

Neuroscience· September 2022

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Characteristics of auditory steady-state responses to different click frequencies in awake intact macaques.
Tomoya Nakamura, Trong Ha Dinh, Makoto Asai, Hiroshi Nishimaru, Jumpei Matsumoto, Takuma Mihara

BMC Neurosci· September 2022

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Electrocorticographic effects of acute ketamine on non-human primate brains.
Tianfang Yan, Katsuyoshi Suzuki, Seiji Kameda, Masashi Maeda, Takuma Mihara

J Neural Eng· April 2022

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Computational identification of variables in neonatal vocalizations predictive for postpubertal social behaviors in a mouse model of 16p11.2 deletion.
Mitsuteru Nakamura, Kenny Ye, Mariel Barbachan E Silva, Takahira Yamauchi, Daniel J Hoeppner, Takuma Mihara

Mol Psychiatry· November 2021

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Gamma power abnormalities in a Fmr1-targeted transgenic rat model of fragile X syndrome.
Naoki Kozono, Ai Okamura, Sokichi Honda, Mitsuyuki Matsumoto, Takuma Mihara

Sci Rep· November 2020

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Effects of (+)-bicuculline, a GABAa receptor antagonist, on auditory steady state response in free-moving rats.
Mayako Yamazaki, Sokichi Honda, Keisuke Tamaki, Megumi Irie, Takuma Mihara

PLoS One· September 2020

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Enhancing Clinical Trials Through Synergistic Gamma Power Analysis.
Sokichi Honda, Mitsuyuki Matsumoto, Katsunori Tajinda, Takuma Mihara

Front Psychiatry· June 2020

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Non-invasive electroencephalographical (EEG) recording system in awake monkeys.
Tomoya Nakamura, Trong Ha Dinh, Makoto Asai, Hiroshi Nishimaru, Jumpei Matsumoto, Takuma Mihara

Heliyon· May 2020

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A novel GABA receptor positive allosteric modulator, ASP8062, exerts analgesic effects in a rat model of fibromyalgia.
Nobuhito Murai, Yuji Kondo, Shinobu Akuzawa, Takuma Mihara, Nobuyuki Shiraishi

Eur J Pharmacol· December 2019

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Auditory Steady State Response; nature and utility as a translational science tool.
Naoki Kozono, Sokichi Honda, Mariko Tada, Kenji Kirihara, Zhilei Zhao, Takuma Mihara

Sci Rep· June 2019

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Fragment-Based Discovery of Pyrimido[1,2-b]indazole PDE10A Inhibitors.
Ayaka Chino, Ryushi Seo, Yasushi Amano, Ichiji Namatame, Wataru Hamaguchi, Takuma Mihara

Chem Pharm Bull (Tokyo)· March 2018

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Amygdala activity associated with social choice in mice.
Takuma Mihara, Kobina Mensah-Brown, Rosanna Sobota, Robert Lin, Robert Featherstone

Behav Brain Res· August 2017

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Oxytocin reduces amygdala activity, increases social interactions, and reduces anxiety-like behavior irrespective of NMDAR antagonism.
Rosanna Sobota, Takuma Mihara, Alexandra Forrest, Robert E Featherstone, Steven J Siegel

Behav Neurosci· August 2015

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Synthesis and in vivo evaluation of novel quinoline derivatives as phosphodiesterase 10A inhibitors.
Wataru Hamaguchi, Naoyuki Masuda, Kiyohiro Samizu, Takuma Mihara, Kaori Takama

Chem Pharm Bull (Tokyo)· July 2015

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Addressing phototoxicity observed in a novel series of biaryl derivatives: discovery of potent, selective and orally active phosphodiesterase 10A inhibitor ASP9436.
Wataru Hamaguchi, Naoyuki Masuda, Satoshi Miyamoto, Shigetoshi Kikuchi, Fumie Narazaki, Takuma Mihara

Bioorg Med Chem· July 2015

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Synthesis, SAR study, and biological evaluation of novel quinoline derivatives as phosphodiesterase 10A inhibitors with reduced CYP3A4 inhibition.
Wataru Hamaguchi, Naoyuki Masuda, Satoshi Miyamoto, Yasuhiro Shiina, Shigetoshi Kikuchi, Takuma Mihara

Bioorg Med Chem· January 2015

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[Ketamine alters socially-evoked activity in the amygdala].
Takuma Mihara, Steven J Siegel

Nihon Yakurigaku Zasshi· December 2014

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Novel benzimidazole derivatives as phosphodiesterase 10A (PDE10A) inhibitors with improved metabolic stability.
Ayaka Chino, Naoyuki Masuda, Yasushi Amano, Kazuya Honbou, Takuma Mihara

Bioorg Med Chem· July 2014

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Design and synthesis of novel benzimidazole derivatives as phosphodiesterase 10A inhibitors with reduced CYP1A2 inhibition.
Wataru Hamaguchi, Naoyuki Masuda, Mai Isomura, Satoshi Miyamoto, Shigetoshi Kikuchi, Takuma Mihara

Bioorg Med Chem· December 2013

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Two models for weight gain and hyperphagia as side effects of atypical antipsychotics in male rats: validation with olanzapine and ziprasidone.
Miwako Shobo, Hiroshi Yamada, Takuma Mihara, Yuji Kondo, Megumi Irie

Behav Brain Res· January 2011

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A novel adenosine A(1) and A(2A) receptor antagonist ASP5854 ameliorates motor impairment in MPTP-treated marmosets: comparison with existing anti-Parkinson's disease drugs.
Takuma Mihara, Akinori Iwashita, Nobuya Matsuoka

Behav Brain Res· December 2008

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Brain adenosine A2A receptor occupancy by a novel A1/A2A receptor antagonist, ASP5854, in rhesus monkeys: relationship to anticataleptic effect.
Takuma Mihara, Akihiro Noda, Hiroshi Arai, Kayoko Mihara, Akinori Iwashita

J Nucl Med· July 2008

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