Publications by authors named "Talat Malik"

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Temporal multi-omics analysis of COVID-19 in end-stage kidney disease.
Emily Stephenson, Erin Macdonald-Dunlop, Lisa M Dratva, Rik G H Lindeboom, Zewen Kelvin Tuong, Talat H Malik

Cell Genom· August 2025

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A novel mutation in EROS (CYBC1) causes chronic granulomatous disease.
Paige M Mortimer, Esme Nichols, Joe Thomas, Rachna Shanbhag, Neha Singh, Talat H Malik

Clin Immunol· October 2023

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Multi-omics identify falling LRRC15 as a COVID-19 severity marker and persistent pro-thrombotic signals in convalescence.
Jack S Gisby, Norzawani B Buang, Artemis Papadaki, Candice L Clarke, Talat H Malik

Nat Commun· December 2022

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Factor H-Related Protein 1 Drives Disease Susceptibility and Prognosis in C3 Glomerulopathy.
Bárbara Márquez-Tirado, Josué Gutiérrez-Tenorio, Agustín Tortajada, Laura Lucientes Continente, Fernando Caravaca-Fontán, Talat H Malik

J Am Soc Nephrol· June 2022

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Homodimeric Minimal Factor H: Tracking and Extended Dosing Studies in Factor H Deficient Mice.
Ola Kamala, Talat H Malik, Thomas M Hallam, Thomas E Cox, Yi Yang

Front Immunol· February 2022

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Adeno-Associated Virus Vector Gene Delivery Elevates Factor I Levels and Downregulates the Complement Alternative Pathway .
Amina Ahmad, Mawj Mandwie, Anna K Dreismann, Christine M Smyth, Helen Doyle, Talat H Malik

Hum Gene Ther· November 2021

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Murine Factor H Co-Produced in Yeast With Protein Disulfide Isomerase Ameliorated C3 Dysregulation in Factor H-Deficient Mice.
Heather Kerr, Andrew P Herbert, Elisavet Makou, Dariusz Abramczyk, Talat H Malik

Front Immunol· October 2021

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Severe COVID-19 is associated with endothelial activation and abnormal glycosylation of von Willebrand factor in patients undergoing hemodialysis.
Golzar Mobayen, Amrita Dhutia, Candice Clarke, Maria Prendecki, Stephen McAdoo, Talat Malik

Res Pract Thromb Haemost· August 2021

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Defining the Glycosaminoglycan Interactions of Complement Factor H-Related Protein 5.
Frederick Gyapon-Quast, Elena Goicoechea de Jorge, Talat Malik, Nian Wu, Jin Yu

J Immunol· July 2021

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Longitudinal proteomic profiling of dialysis patients with COVID-19 reveals markers of severity and predictors of death.
Jack Gisby, Candice L Clarke, Nicholas Medjeral-Thomas, Talat H Malik, Artemis Papadaki

Elife· March 2021

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Gain-of-function factor H-related 5 protein impairs glomerular complement regulation resulting in kidney damage.
Talat H Malik, Daniel P Gitterman, Deborah P Lavin, Hannah J Lomax-Browne, E Christina Hiemeyer

Proc Natl Acad Sci U S A· March 2021

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B cell OX40L supports T follicular helper cell development and contributes to SLE pathogenesis.
Andrea Cortini, Ursula Ellinghaus, Talat H Malik, Deborah S Cunninghame Graham, Marina Botto

Ann Rheum Dis· December 2017

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Increased Autoreactivity of the Complement-Activating Molecule Mannan-Binding Lectin in a Type 1 Diabetes Model.
Jakob Appel Østergaard, Marieta Milkova Ruseva, Talat Habib Malik, Ingeborg Torp Hoffmann-Petersen, Matthew Caleb Pickering

J Diabetes Res· December 2016

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Partial Complement Factor H Deficiency Associates with C3 Glomerulopathy and Thrombotic Microangiopathy.
Katherine A Vernon, Marieta M Ruseva, H Terence Cook, Marina Botto, Talat H Malik

J Am Soc Nephrol· May 2016

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Near Infrared Fluorescence (NIRF) Molecular Imaging of Oxidized LDL with an Autoantibody in Experimental Atherosclerosis.
Ramzi Y Khamis, Kevin J Woollard, Gareth D Hyde, Joseph J Boyle, Colin Bicknell, Talat H Malik

Sci Rep· February 2016

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Triglyceride-Rich Lipoproteins Modulate the Distribution and Extravasation of Ly6C/Gr1(low) Monocytes.
Maha F Saja, Lucie Baudino, William D Jackson, H Terence Cook, Talat H Malik

Cell Rep· September 2015

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Competition between antagonistic complement factors for a single protein on N. meningitidis rules disease susceptibility.
Joseph J E Caesar, Hayley Lavender, Philip N Ward, Rachel M Exley, Jack Eaton, Talat H Malik

Elife· December 2014

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Requirement of JNK1 for endothelial cell injury in atherogenesis.
Narges Amini, Joseph J Boyle, Britta Moers, Christina M Warboys, Talat H Malik

Atherosclerosis· August 2014

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IL-10-producing regulatory B cells induced by IL-33 (Breg(IL-33)) effectively attenuate mucosal inflammatory responses in the gut.
Susanne Sattler, Guang-Sheng Ling, Damo Xu, Leonie Hussaarts, Andreas Romaine, Talat Malik

J Autoimmun· May 2014

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A novel CFHR5 fusion protein causes C3 glomerulopathy in a family without Cypriot ancestry.
Nicholas Medjeral-Thomas, Talat H Malik, Mitali P Patel, Tibor Toth, H Terence Cook

Kidney Int· April 2014

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Nonfunctional variant 3 factor H binding proteins as meningococcal vaccine candidates.
Stijn van der Veen, Steven Johnson, Ilse Jongerius, Talat Malik, Alessia Genovese

Infect Immun· March 2014

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Trans-ancestral studies fine map the SLE-susceptibility locus TNFSF4.
Harinder Manku, Carl D Langefeld, Sandra G Guerra, Talat H Malik, Marta Alarcon-Riquelme

PLoS Genet· January 2014

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Complement component C3 plays a critical role in protecting the aging retina in a murine model of age-related macular degeneration.
Jaimie Hoh Kam, Eva Lenassi, Talat H Malik, Matthew C Pickering, Glen Jeffery

Am J Pathol· August 2013

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C3 glomerulopathy-associated CFHR1 mutation alters FHR oligomerization and complement regulation.
Agustín Tortajada, Hugo Yébenes, Cynthia Abarrategui-Garrido, Jaouad Anter, Jesús M García-Fernández, Talat H Malik

J Clin Invest· June 2013

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Dimerization of complement factor H-related proteins modulates complement activation in vivo.
Elena Goicoechea de Jorge, Joseph J E Caesar, Talat H Malik, Mitali Patel, Matthew Colledge

Proc Natl Acad Sci U S A· March 2013

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