Publications by authors named "Tanja A Gruber"

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Infant acute lymphoblastic leukaemia-Progress from worldwide clinical efforts.
Neil Barrett, Tanja A Gruber, Takako Miyamura, Alasdair Duguid, Janine Stutterheim

Br J Haematol· December 2025

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Transcriptomic Diversity of Pediatric Acute Myeloid Leukemia Genetic Drivers Correlates With Clinical Outcome and Expression of Stemness-Related Genes.
Quenton Rashawn Bubb, Elena Sotillo, Rebecca M Richards, Crystal L Mackall, Tanja A Gruber

Cancer Med· November 2025

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Clonal Evolution of Pediatric Acute Myeloid Leukemia and Its Contribution to Disease Relapse.
Masayuki Umeda, Pandurang Kolekar, Anna Lw Huskey, Shruthi Suryaprakash, Jing Ma, Tanja A Gruber

medRxiv· November 2025

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BH3 mimetic therapies for CBFA2T3::GLIS2 pediatric acute megakaryoblastic leukemia.
Caroline Capdevielle, Sarah St-Amand, Mathieu Neault, Tanja A Gruber, Sonia Cellot

Trends Mol Med· October 2025

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The genomic landscape of relapsed infant and childhood KMT2A-rearranged acute leukemia.
Louise Ahlgren, Mattias Pilheden, Helena Sturesson, Guangchun Song, Michael P Walsh, Tanja A Gruber

Nat Commun· October 2025

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CIC-Rearrangements in Pediatric Acute Erythroid Leukemia/Erythroblastic Sarcoma.
Alexandra L Chang-Graham, Thien Nguyen, Jean Oak, Oscar Silva, Tanja A Gruber

Pediatr Blood Cancer· September 2025

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Development of multivalent CAR T cells as dual immunotherapy and conditioning agents.
Quenton Rashawn Bubb, Mohammad Balood, Gabe Eduardo Seir, Leah Swartzrock, Ethan Haslett, Tanja A Gruber

Mol Ther Oncol· March 2025

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An inflammatory state defines a high-risk T-lineage acute lymphoblastic leukemia subgroup.
Mark Gower, Ximing Li, Alicia G Aguilar-Navarro, Brian Lin, Minerva Fernandez, Tanja A Gruber

Sci Transl Med· January 2025

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CBFA2T3-GLIS2 mediates transcriptional regulation of developmental pathways through a gene regulatory network.
Elizabeth A R Garfinkle, Pratima Nallagatla, Binay Sahoo, Jinjun Dang, Mohammad Balood, Tanja A Gruber

Nat Commun· October 2024

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CBFA2T3::GLIS2 pediatric acute megakaryoblastic leukemia is sensitive to BCL-XL inhibition by navitoclax and DT2216.
Verena Gress, Mathieu Roussy, Luc Boulianne, Mélanie Bilodeau, Sophie Cardin, Tanja A Gruber

Blood Adv· January 2024

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Genome editing-induced t(4;11) chromosomal translocations model B cell precursor acute lymphoblastic leukemias with KMT2A-AFF1 fusion.
Feng Pan, Jolanda Sarno, Johan Jeong, Xin Yang, Astraea Jager, Tanja A Gruber

J Clin Invest· January 2024

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CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax.
Mathieu Neault, Charles-Étienne Lebert-Ghali, Marilaine Fournier, Caroline Capdevielle, Elizabeth A R Garfinkle, Tanja A Gruber

Cell Rep· September 2023

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Malignant Progression of an Ancestral Bone Marrow Clone Harboring a CIC-NUTM2A Fusion in Isolated Myeloid Sarcoma.
Jennifer L Kamens, Jinjun Dang, Timothy I Shaw, Alexander M Gout, Scott Newman, Tanja A Gruber

Mol Cancer Res· April 2023

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Author Correction: Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia.
Jennifer L Kamens, Stephanie Nance, Cary Koss, Beisi Xu, Anitria Cotton, Tanja A Gruber

Nat Commun· March 2023

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Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia.
Jennifer L Kamens, Stephanie Nance, Cary Koss, Beisi Xu, Anitria Cotton, Tanja A Gruber

Nat Commun· February 2023

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Analysis of rare driving events in pediatric acute myeloid leukemia.
Sanne Noort, Jolieke van Oosterwijk, Jing Ma, Elizabeth A R Garfinkle, Stephanie Nance, Tanja A Gruber

Haematologica· January 2023

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An inflammatory state remodels the immune microenvironment and improves risk stratification in acute myeloid leukemia.
Audrey Lasry, Bettina Nadorp, Maarten Fornerod, Deedra Nicolet, Huiyun Wu, Tanja A Gruber

Nat Cancer· January 2023

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Author Correction: An inflammatory state remodels the immune microenvironment and improves risk stratification in acute myeloid leukemia.
Audrey Lasry, Bettina Nadorp, Maarten Fornerod, Deedra Nicolet, Huiyun Wu, Tanja A Gruber

Nat Cancer· January 2023

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Clofarabine treatment of KMT2Ar infantile patients with acute lymphoblastic leukemia in St. Jude Total Therapy Study 16.
Tanja A Gruber, Deqing Pei, John Choi, Cheng Cheng, Elaine Coustan-Smith

Blood Adv· December 2022

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A CRISPR/Cas9 engineered Mpl mouse model recapitulates human myelofibrosis.
Fabienne R S Adriaanse, Jennifer L Kamens, Peter Vogel, Sadie M Sakurada, Shondra M Pruett-Miller, Tanja A Gruber

Leukemia· October 2022

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The development of therapy related myeloid neoplasms in childhood cancer survivors.
Esther A Obeng, Tanja A Gruber

Trends Cancer· October 2022

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Therapy-related myeloid neoplasms resembling juvenile myelomonocytic leukemia: a case series and review of the literature.
Astrid Wintering, Stephen Smith, Beng Fuh, Arun Rangaswami, Gary Dahl, Tanja A Gruber

Pediatr Blood Cancer· May 2022

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Integrative Genomic Analysis of Pediatric Myeloid-Related Acute Leukemias Identifies Novel Subtypes and Prognostic Indicators.
Maarten Fornerod, Jing Ma, Sanne Noort, Yu Liu, Michael P Walsh, Tanja A Gruber

Blood Cancer Discov· November 2021

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Favorable outcome of NUTM1-rearranged infant and pediatric B cell precursor acute lymphoblastic leukemia in a collaborative international study.
Judith M Boer, Maria Grazia Valsecchi, Femke M Hormann, Željko Antić, Marketa Zaliova

Leukemia· October 2021

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Clinical significance of novel subtypes of acute lymphoblastic leukemia in the context of minimal residual disease-directed therapy.
Sima Jeha, John Choi, Kathryn G Roberts, Deqing Pei, Elaine Coustan-Smith, Tanja A Gruber

Blood Cancer Discov· July 2021

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