Publications by authors named "Tarah A Word"

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Structure-activity optimization of ryanodine receptor modulators for the treatment of catecholaminergic polymorphic ventricular tachycardia.
Oliver M Moore, Martha Sibrian-Vazquez, Jose Alberto Navarro-Garcia, Yuriana Aguilar-Sanchez, Mara R Turkieltaub-Paredes, Tarah A Word

Heart Rhythm· July 2025

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ATP1A3 Variants, Variably Penetrant Short QT Intervals, and Lethal Ventricular Arrhythmias.
Mary E Moya-Mendez, Minu-Tshyeto Bidzimou, Padmapriya Muralidharan, Zhushan Zhang, Jordan E Ezekian, Tarah A Word

JAMA Pediatr· May 2025

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Long-term efficacy and safety of cardiac genome editing for catecholaminergic polymorphic ventricular tachycardia.
Oliver M Moore, Yuriana Aguilar-Sanchez, Satadru K Lahiri, Mohit M Hulsurkar, J Alberto Navarro-Garcia, Tarah A Word

J Cardiovasc Aging· January 2024

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Nonsense Variant PRDM16-Q187X Causes Impaired Myocardial Development and TGF-β Signaling Resulting in Noncompaction Cardiomyopathy in Humans and Mice.
Bo Sun, Omid M T Rouzbehani, Ryan J Kramer, Rajeshwary Ghosh, Robin M Perelli, Tarah A Word

Circ Heart Fail· December 2023

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Reduction in Junctophilin 2 Expression in Cardiac Nodal Tissue Results in Intracellular Calcium-Driven Increase in Nodal Cell Automaticity.
Andrew P Landstrom, Qixin Yang, Bo Sun, Robin M Perelli, Minu-Tshyeto Bidzimou, Tarah A Word

Circ Arrhythm Electrophysiol· February 2023

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Efficacy of RyR2 inhibitor EL20 in induced pluripotent stem cell-derived cardiomyocytes from a patient with catecholaminergic polymorphic ventricular tachycardia.
Tarah A Word, Ann P Quick, Christina Y Miyake, Mayra K Shak, Xiaolu Pan

J Cell Mol Med· June 2021

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Reversible cardiac disease features in an inducible CUG repeat RNA-expressing mouse model of myotonic dystrophy.
Ashish N Rao, Hannah M Campbell, Xiangnan Guan, Tarah A Word, Xander Ht Wehrens

JCI Insight· March 2021

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Loss of SPEG Inhibitory Phosphorylation of Ryanodine Receptor Type-2 Promotes Atrial Fibrillation.
Hannah M Campbell, Ann P Quick, Issam Abu-Taha, David Y Chiang, Carlos F Kramm, Tarah A Word

Circulation· September 2020

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Calmodulin kinase II regulates atrial myocyte late sodium current, calcium handling, and atrial arrhythmia.
Amara Greer-Short, Hassan Musa, Katherina M Alsina, Li Ni, Tarah A Word

Heart Rhythm· March 2020

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Targeting pathological leak of ryanodine receptors: preclinical progress and the potential impact on treatments for cardiac arrhythmias and heart failure.
Patrick Connell, Tarah A Word, Xander H T Wehrens

Expert Opin Ther Targets· January 2020

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Loss of Protein Phosphatase 1 Regulatory Subunit PPP1R3A Promotes Atrial Fibrillation.
Katherina M Alsina, Mohit Hulsurkar, Sören Brandenburg, Daniel Kownatzki-Danger, Christof Lenz, Tarah A Word

Circulation· August 2019

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In Vivo Ryr2 Editing Corrects Catecholaminergic Polymorphic Ventricular Tachycardia.
Xiaolu Pan, Leonne Philippen, Satadru K Lahiri, Ciaran Lee, So Hyun Park, Tarah A Word

Circ Res· September 2018

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EL20, a potent antiarrhythmic compound, selectively inhibits calmodulin-deficient ryanodine receptor type 2.
Robert C Klipp, Na Li, Qiongling Wang, Tarah A Word, Martha Sibrian-Vazquez

Heart Rhythm· April 2018

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Time resolved calorimetry of photo-induced folding in horse heart cytochrome c at high pH.
Tarah A Word, Randy W Larsen

Arch Biochem Biophys· February 2017

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Treatment of catecholaminergic polymorphic ventricular tachycardia in mice using novel RyR2-modifying drugs.
Na Li, Qiongling Wang, Martha Sibrian-Vazquez, Robert C Klipp, Julia O Reynolds, Tarah A Word

Int J Cardiol· January 2017

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Photoacoustic calorimetry studies of CO photo-dissociation from chloramine-T modified horse heart cytochrome-c.
Tarah A Word, Randy W Larsen

Arch Biochem Biophys· December 2016

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Removal of pain-relieving drugs from aqueous solutions using Octolig and selected metalloligs.
Dean F Martin, Tanya Sehgal, Tarah A Word

J Environ Sci Health A Tox Hazard Subst Environ Eng· January 2016

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Removal of selected NSAIDs (nonsteroidal anti-inflammatory drugs) in aqueous samples by Octolig®.
Dean F Martin, Jenny Mojarena Martin, Tarah A Word

J Environ Sci Health A Tox Hazard Subst Environ Eng· January 2016

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