Publications by authors named "Tarek Okda"

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Novel benzoxazole-based hybrids as multi-target inhibitors of aromatase, EGFR, and PI3K with potential anti-breast cancer activity.
Mai S El-Shoukrofy, Mai E Amr, Tarek M Okda, A-Mohsen M E Omar, Omaima M AboulWafa

Bioorg Med Chem· February 2026

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Design, synthesis, and antiproliferative efficacy of an innovative series of triazino[5,6-b]indole derivatives targeting EGFR, CD1, Hsp90, PI3K, and ERK/AKT as key molecular targets in cancer therapy.
Eman S Ezz-ElDien, Waleed A Badawi, Mohamed A El-Atawy, Mohammed Elhag, Ezzat A Hamed, Tarek M Okda

Eur J Med Chem· January 2026

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Design and synthesis of multitarget triazinoindole derivatives with potent antiproliferative activity: Targeting EGFR, SIRT1, MDM2, Hsp90, PI3K, p53, and caspase-9.
Waleed A Badawi, Eman S Ezz-ElDien, Mohamed A El-Atawy, Alaa Z Omar, Ezzat A Hamed, Tarek M Okda

Bioorg Chem· October 2025

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Enhanced antitumour efficacy of ferulic acid nanoparticles in combination with doxorubicin - a promising strategy for breast cancer treatment.
Alshimaa F Salama, Gamal A Omran, Ahmad M Salahuddin, Heba M Abd-El-Azim, Ahmed Noreldin, Tarek M Okda

Contemp Oncol (Pozn)· October 2025

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Developing new anticancer agents: Design, synthesis, biological evaluation and in silico study of several functionalized pyrimidine-5-carbonitriles as small molecules modulators targeting breast cancer.
Waleed A Badawi, Tarek M Okda, Shrouk M Abd El Wahab, Eman S Ezz-ElDien, Omaima M AboulWafa

Bioorg Chem· December 2024

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Design and Optimization of Sesamol Nanosuspensions to Potentiate the Anti-Tumor Activity of Epirubicin against Ehrlich Solid Carcinoma-Bearing Mice.
Kholoud A Elzanaty, Gamal A Omran, Ehab Kotb Elmahallawy, Ashraf Albrakati, Ayman A Saleh, Tarek M Okda

Pharmaceutics· July 2024

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Ameliorative effect of licorice extract against the detrimental effect of glyphosate-based pesticide: Toxicity and health.
Ahmed N Elkattan, Sayad El-Saadany, Mohamed Azzazy, Tarek M Okda, Maha Mamdouh

Heliyon· May 2024

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Design, synthesis and molecular docking study of new pyrimidine-based hydrazones with selective anti-proliferative activity against MCF-7 and MDA-MB-231 human breast cancer cell lines.
Waleed A Badawi, Mohamed Samir, Hazem M Fathy, Tarek M Okda, Mohamed H Noureldin

Bioorg Chem· September 2023

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Insights into HPLC-MS/MS Analysis, Antioxidant and Cytotoxic Activity of against Different Types of Cancer Cell Lines.
Mohamed Fayez Dekinash, Tarek M Okda, Ehab Kotb Elmahallawy, Fathy Kandil El-Fiky, Gamal Abd El Hay Omran

Pharmaceuticals (Basel)· November 2022

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Quercetin potentiates 5-fluorouracil effects in human colon cancer cells through targeting the Wnt/β-catenin signalling pathway: the role of miR-27a.
Ghada T Terana, Mohamed M Abd-Alhaseeb, Gamal A Omran, Tarek M Okda

Contemp Oncol (Pozn)· October 2022

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Baicalin; a promising chemopreventive agent, enhances the antitumor effect of 5-FU against breast cancer and inhibits tumor growth and angiogenesis in Ehrlich solid tumor.
Nisreen H Shehatta, Tarek M Okda, Gamal A Omran, Mohammad M Abd-Alhaseeb

Biomed Pharmacother· February 2022

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A Novel Role of Galectin-3 and Thyroglobulin in Prognosis and Differentiation of Different Stages of Thyroid Cancer and Elucidation of the Potential Contribution of Bcl-2, IL-8 and TNF-α.
Tarek M Okda, Gamal M K Atwa, Ahmed Fathy Eldehn, Naief Dahran, Khalaf F Alsharif

Biomedicines· February 2022

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The influence of vinpocetine alone or in combination with Epigallocatechin-3-gallate, Coenzyme COQ10, Vitamin E and Selenium as a potential neuroprotective combination against aluminium-induced Alzheimer's disease in Wistar Albino Rats.
Azza A Ali, Mona G Khalil, Doaa M Abd El-Latif, Tarek Okda, Aya I Abdelaziz

Arch Gerontol Geriatr· December 2021

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Prognostic Value of Serum Thyroglobulin and Anti-Thyroglobulin Antibody in Thyroid Carcinoma Patients following Thyroidectomy.
Hashem O Zahra, Gamal A Omran, Ahmed G Gewely, Ahmed Fathy Eldehn, Walied Abdo, Tarek M Okda

Diagnostics (Basel)· November 2021

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The antitumour effect of galangin and luteolin with doxorubicin on chemically induced hepatocellular carcinoma in rats.
Gamal Atwa, Gamal Omran, Atef Abd Elbaky, Tarek Okda

Contemp Oncol (Pozn)· October 2021

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Design and Optimization of Orally Administered Luteolin Nanoethosomes to Enhance Its Anti-Tumor Activity against Hepatocellular Carcinoma.
Mahmoud M A Elsayed, Tarek M Okda, Gamal M K Atwa, Gamal A Omran, Atef E Abd Elbaky

Pharmaceutics· May 2021

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Phytic acid potentiates oxaliplatin effects in colorectal cancer induced by 1,2-DMH: the role of miR-224 and miR-200a.
Tarek M Okda, Mohamed A Katry, Noha M Ragab, Abdel-Gawad S Shalkami

Contemp Oncol (Pozn)· May 2021

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Chemopreventive and anticancer activities of indomethacin and vitamin D combination on colorectal cancer induced by 1,2-dimethylhydrazine in rats.
Tarek M Okda, Sary K Abd-Elghaffar, Mohamed A Katary, Mohammad M Abd-Alhaseeb

Biomed Rep· February 2021

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Association between serum soluble Toll-like receptor 2 and 4 and the risk of breast cancer.
Ghada El-Kharashy, Ahmed Gowily, Tarek Okda, Maha Houssen

Mol Clin Oncol· February 2021

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Serum soluble Toll-like receptor 4 and the risk of hepatocellular carcinoma in hepatitis C virus patients.
Maha Elkammah, Ahmed Gowily, Tarek Okda, Maha Houssen

Contemp Oncol (Pozn)· January 2021

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Serum soluble toll-like receptor 2 and 4 as diagnostic and prognostic biomarkers for non-Hodgkin lymphoma.
Nouran Fakhry, Ahmed Gowily, Tarek Okda, Maha Houssen

Contemp Oncol (Pozn)· October 2020

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