Publications by authors named "Teclegiorgis Gebremariam"

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Efficacy assessments of EL219, a next-generation polyene antifungal, in immunosuppressed mice infected with drug-sensitive and drug-resistant isolates.
Eman G Youssef, Teclegiorgis Gebremariam, Yiyou Gu, Hoja Patterson, Sondus Alkhazraji

Antimicrob Agents Chemother· December 2025

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Next-generation Candida albicans vaccine VXV-01 containing recombinant Als3p and Hyr1p antigens for invasive Candida infections.
Shakti Singh, Eman G Youssef, Ashley Barbarino, Haley Hautau, Sunna Nabeela, Teclegiorgis Gebremariam

Sci Rep· December 2025

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β-Glucan Chitosan Particle Provides Cross-Protection Against Multi-Drug- Resistant Candida auris.
Shakti Singh, Ashley Barbarino, Eman G Youssef, Kaustav Das Gupta, Sunna Nabeela, Teclegiorgis Gebremariam

Res Sq· November 2025

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Next-generation Candida albicans recombinant Als3p and Hyr1p dual antigen vaccine for invasive Candida infections.
Shakti Singh, Eman G Youssef, Ashley Barbarino, Haley Hautau, Sunna Nabeela, Teclegiorgis Gebremariam

Res Sq· September 2025

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Efficacy assessments of SF001, a next-generation polyene antifungal, in a neutropenic mouse model of invasive fusariosis.
Teclegiorgis Gebremariam, Yiyou Gu, Hoja Patterson, Eman Youssef, Sondus Alkhazraji

Antimicrob Agents Chemother· May 2025

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A humanized antibody against mucormycosis targets angioinvasion and augments the host immune response.
Yiyou Gu, Shakti Singh, Abdullah Alqarihi, Sondus Alkhazraji, Teclegiorgis Gebremariam

Sci Transl Med· March 2025

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Efficacy of an oral lipid nanocrystal formulation of amphotericin B (MAT2203) in the neutropenic mouse model of pulmonary mucormycosis.
Yiyou Gu, Teclegiorgis Gebremariam, Sondus Alkhazraji, Eman Youssef, Sabrina El-Gamal

Antimicrob Agents Chemother· June 2024

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Ibrexafungerp is efficacious in a neutropenic murine model of pulmonary mucormycosis as monotherapy and combined with liposomal amphotericin B.
Teclegiorgis Gebremariam, Sondus Alkhazraji, Yiyou Gu, Laura K Najvar, Katyna Borroto-Esoda

Antimicrob Agents Chemother· May 2024

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Tuning sterol extraction kinetics yields a renal-sparing polyene antifungal.
Arun Maji, Corinne P Soutar, Jiabao Zhang, Agnieszka Lewandowska, Brice E Uno, Teclegiorgis Gebremariam

Nature· November 2023

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Efficacy of an oral lipid nanocrystal (LNC) formulation of amphotericin B (MAT2203) in the neutropenic mouse model of pulmonary mucormycosis.
Yiyou Gu, Teclegiorgis Gebremariam, Sondus Alkhazraji, Eman Youssef, Sabrina El-Gamal

bioRxiv· November 2023

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Genes Are Necessary for Normal Spore Formation and Virulence in .
Csilla Szebenyi, Yiyou Gu, Teclegiorgis Gebremariam, Sándor Kocsubé, Sándor Kiss-Vetráb

mBio· February 2023

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Protective Efficacy of Anti-Hyr1p Monoclonal Antibody against Systemic Candidiasis Due to Multi-Drug-Resistant .
Shakti Singh, Ashley Barbarino, Eman G Youssef, Declan Coleman, Teclegiorgis Gebremariam

J Fungi (Basel)· January 2023

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The Combination Treatment of Fosmanogepix and Liposomal Amphotericin B Is Superior to Monotherapy in Treating Experimental Invasive Mold Infections.
Teclegiorgis Gebremariam, Yiyou Gu, Sondus Alkhazraji, Eman Youssef, Karen Joy Shaw

Antimicrob Agents Chemother· July 2022

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A bacterial endosymbiont of the fungus Rhizopus microsporus drives phagocyte evasion and opportunistic virulence.
Herbert Itabangi, Poppy C S Sephton-Clark, Diana P Tamayo, Xin Zhou, Georgina P Starling, Teclegiorgis Gebremariam

Curr Biol· March 2022

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Combination treatment of liposomal amphotericin B and isavuconazole is synergistic in treating experimental mucormycosis.
Teclegiorgis Gebremariam, Yiyou Gu, Shakti Singh, Therese M Kitt, Ashraf S Ibrahim

J Antimicrob Chemother· September 2021

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Evaluation of Sex Differences in Murine Diabetic Ketoacidosis and Neutropenic Models of Invasive Mucormycosis.
Teclegiorgis Gebremariam, Sondus Alkhazraji, Abdullah Alqarihi, Nathan P Wiederhold, Laura K Najvar

J Fungi (Basel)· April 2021

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Monoclonal IgM Antibodies Targeting Hyr1 Provide Cross-Kingdom Protection Against Gram-Negative Bacteria.
Eman G Youssef, Lina Zhang, Sondus Alkhazraji, Teclegiorgis Gebremariam, Shakti Singh

Front Immunol· March 2021

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Mucoricin is a ricin-like toxin that is critical for the pathogenesis of mucormycosis.
Sameh S M Soliman, Clara Baldin, Yiyou Gu, Shakti Singh, Teclegiorgis Gebremariam

Nat Microbiol· March 2021

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Preserving Vascular Integrity Protects Mice against Multidrug-Resistant Gram-Negative Bacterial Infection.
Teclegiorgis Gebremariam, Lina Zhang, Sondus Alkhazraji, Yiyou Gu, Eman G Youssef

Antimicrob Agents Chemother· July 2020

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Selective inhibition of Rhizopus eumelanin biosynthesis by novel natural product scaffold-based designs caused significant inhibition of fungal pathogenesis.
Sameh S M Soliman, Rania Hamdy, Samia A Elseginy, Teclegiorgis Gebremariam, Alshaimaa M Hamoda

Biochem J· July 2020

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GRP78 and Integrins Play Different Roles in Host Cell Invasion during Mucormycosis.
Abdullah Alqarihi, Teclegiorgis Gebremariam, Yiyou Gu, Marc Swidergall, Sondus Alkhazraji

mBio· June 2020

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Fosmanogepix (APX001) Is Effective in the Treatment of Pulmonary Murine Mucormycosis Due to Rhizopus arrhizus.
Teclegiorgis Gebremariam, Sondus Alkhazraji, Abdullah Alqarihi, Nathan P Wiederhold, Karen Joy Shaw

Antimicrob Agents Chemother· May 2020

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Fosmanogepix (APX001) Is Effective in the Treatment of Immunocompromised Mice Infected with Invasive Pulmonary Scedosporiosis or Disseminated Fusariosis.
Sondus Alkhazraji, Teclegiorgis Gebremariam, Abdullah Alqarihi, Yiyou Gu, Zeinab Mamouei

Antimicrob Agents Chemother· February 2020

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Galactomannan Is a Biomarker of Fosmanogepix (APX001) Efficacy in Treating Experimental Invasive Pulmonary Aspergillosis.
Teclegiorgis Gebremariam, Sondus Alkhazraji, Yiyou Gu, Shakti Singh, Abdullah Alqarihi

Antimicrob Agents Chemother· December 2019

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Anti-CotH3 antibodies protect mice from mucormycosis by prevention of invasion and augmenting opsonophagocytosis.
Teclegiorgis Gebremariam, Sondus Alkhazraji, Sameh S M Soliman, Yiyou Gu, Heewon H Jeon

Sci Adv· June 2019

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