Publications by authors named "Ted Johnson"

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Discovery of PF-07265028, A Selective Small Molecule Inhibitor of Hematopoietic Progenitor Kinase 1 (HPK1) for the Treatment of Cancer.
Rebecca A Gallego, Sujin Cho-Schultz, Matthew Del Bel, Anne-Marie Dechert-Schmitt, Joyann S Donaldson, Eric Johnson, Ted W Johnson

J Med Chem· December 2024

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Crossing the Halfway Point: Aptamer-Based, Highly Multiplexed Assay for the Assessment of the Proteome.
Stephan Kraemer, Daniel J Schneider, Clare Paterson, Darryl Perry, Matthew J Westacott, Ted Johnson

J Proteome Res· November 2024

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Discovery of Highly Selective Inhibitors of Microtubule-Associated Serine/Threonine Kinase-like (MASTL).
Rebecca A Gallego, Stephanie Scales, Chad Toledo, Marin Auth, Louise Bernier, Ted W Johnson

J Med Chem· November 2024

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The Choice of Osteosynthesis for Distal Radius Fractures: A Matter of Taste, Fracture Instability, or Patient-Related Factors? A Retrospective Study of Functional Outcome in 346 Distal Radius Fractures Operated With Percutaneous Wires or Volar Plate Fixation.
Karl-Johan Holmqvist, Ted Johnson, Lotta Fornander

Hand (N Y)· May 2024

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Design and Synthesis of Functionally Active 5-Amino-6-Aryl Pyrrolopyrimidine Inhibitors of Hematopoietic Progenitor Kinase 1.
Rebecca A Gallego, Louise Bernier, Hui Chen, Sujin Cho-Schultz, Loanne Chung, Eric Johnson, Ted W Johnson

J Med Chem· April 2023

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COVID-19 and the Motorcycle Taxi Sector in Sub-Saharan African Cities: A Key Stakeholders' Perspective.
Krijn Peters, Jack Jenkins, Simon Ntramah, James Vincent, Patrick Hayombe, Ted Johnson

Transp Res Rec· April 2023

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Wastewater sequencing reveals early cryptic SARS-CoV-2 variant transmission.
Smruthi Karthikeyan, Joshua I Levy, Peter De Hoff, Greg Humphrey, Amanda Birmingham, Ted Johnson

Nature· September 2022

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Analysis of lorlatinib analogs reveals a roadmap for targeting diverse compound resistance mutations in ALK-positive lung cancer.
Aya Shiba-Ishii, Ted W Johnson, Ibiayi Dagogo-Jack, Mari Mino-Kenudson, Theodore R Johnson

Nat Cancer· June 2022

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Wastewater sequencing uncovers early, cryptic SARS-CoV-2 variant transmission.
Smruthi Karthikeyan, Joshua I Levy, Peter De Hoff, Greg Humphrey, Amanda Birmingham, Ted Johnson

medRxiv· April 2022

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LTK fusions: A new target emerges in non-small cell lung cancer.
Alissa J Cooper, Lecia V Sequist, Ted W Johnson, Jessica J Lin

Cancer Cell· January 2022

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Spectrum of Mechanisms of Resistance to Crizotinib and Lorlatinib in Fusion-Positive Lung Cancer.
Jessica J Lin, Noura J Choudhury, Satoshi Yoda, Viola W Zhu, Ted W Johnson

Clin Cancer Res· May 2021

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Atypical Presentations among Older Adults with COVID-19 Disease: A Need for Broadening the Differential Diagnosis.
Ugochi Ohuabunwa, Joyce Turner, Ted Johnson

Gerontol Geriatr Med· March 2021

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Multiple conformational states of the HPK1 kinase domain in complex with sunitinib reveal the structural changes accompanying HPK1 trans-regulation.
Eric Johnson, Michele McTigue, Rebecca A Gallego, Ted W Johnson, Sergei Timofeevski

J Biol Chem· June 2019

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Reviving B-Factors: Activating ALK Mutations Increase Protein Dynamics of the Unphosphorylated Kinase.
Ted W Johnson, Ben Bolanos, Alexei Brooun, Rebecca A Gallego, Dan Gehlhaar

ACS Med Chem Lett· September 2018

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Reviving B-Factors: Retrospective Normalized B-Factor Analysis of c-ros Oncogene 1 Receptor Tyrosine Kinase and Anaplastic Lymphoma Kinase L1196M with Crizotinib and Lorlatinib.
Ted W Johnson, Rebecca A Gallego, Alexei Brooun, Dan Gehlhaar, Michele McTigue

ACS Med Chem Lett· September 2018

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Lipophilic Efficiency as an Important Metric in Drug Design.
Ted W Johnson, Rebecca A Gallego, Martin P Edwards

J Med Chem· August 2018

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Sequential ALK Inhibitors Can Select for Lorlatinib-Resistant Compound Mutations in ALK-Positive Lung Cancer.
Satoshi Yoda, Jessica J Lin, Michael S Lawrence, Benjamin J Burke, Luc Friboulet, Ted W Johnson

Cancer Discov· June 2018

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A multipollutant evaluation of APEX using microenvironmental ozone, carbon monoxide, and particulate matter (PM) concentrations measured in Los Angeles by the exposure classification project.
Ted R Johnson, John E Langstaff, Stephen Graham, Eric M Fujita, David E Campbell

Cogent Environ Sci· March 2018

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The Axl kinase domain in complex with a macrocyclic inhibitor offers first structural insights into an active TAM receptor kinase.
Ketan S Gajiwala, Neil Grodsky, Ben Bolaños, Junli Feng, RoseAnn Ferre, Ted W Johnson

J Biol Chem· September 2017

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Discovery of 1-{(3R,4R)-3-[({5-Chloro-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-methoxypyrrolidin-1-yl}prop-2-en-1-one (PF-06459988), a Potent, WT Sparing, Irreversible Inhibitor of T790M-Containing EGFR Mutants.
Hengmiao Cheng, Sajiv K Nair, Brion W Murray, Chau Almaden, Simon Bailey, Ted O Johnson

J Med Chem· March 2016

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Conformational Studies and Atropisomerism Kinetics of the ALK Clinical Candidate Lorlatinib (PF-06463922) and Desmethyl Congeners.
Jeff Elleraas, Jason Ewanicki, Ted W Johnson, Neal W Sach, Michael R Collins

Angew Chem Int Ed Engl· March 2016

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Resensitization to Crizotinib by the Lorlatinib ALK Resistance Mutation L1198F.
Alice T Shaw, Luc Friboulet, Ignaty Leshchiner, Justin F Gainor, Simon Bergqvist, Ted W Johnson

N Engl J Med· January 2016

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Effects of Activating Mutations on EGFR Cellular Protein Turnover and Amino Acid Recycling Determined Using SILAC Mass Spectrometry.
Michael J Greig, Sherry Niessen, Scott L Weinrich, Jun Li Feng, Manli Shi, Ted O Johnson

Int J Cell Biol· December 2015

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CNS Anticancer Drug Discovery and Development Conference White Paper.
Victor A Levin, Peter J Tonge, James M Gallo, Marc R Birtwistle, Arvin C Dar, Ted W Johnson

Neuro Oncol· November 2015

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Recovery and Stability of Δ9-Tetrahydrocannabinol Using the Oral-Eze® Oral Fluid Collection System and Intercept® Oral Specimen Collection Device.
Kimberly L Samano, Lakshmi Anne, Ted Johnson, Kenneth Tang, R H Barry Sample

J Anal Toxicol· October 2015

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