Publications by authors named "Terence Kin-Wah Lee"

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Adipocyte-derived FABP4 promotes metabolism-associated steatotic liver-induced hepatocellular carcinoma by driving ITGB1-mediated β-catenin activation.
Carmen Oi Ning Leung, Shilpa Gurung, Katherine Po Sin Chung, Rainbow Wing Hei Leung, Martina Mang Leng Lei, Terence Kin Wah Lee

J Clin Invest· December 2025

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Wild-type KRAS activation drives evasion of interferon-mediated immunity and resistance to immunotherapy in hepatocellular carcinoma.
Martina Mang Leng Lei, Carmen Oi Ning Leung, Rainbow Wing Hei Leung, Xue Qian Wu, Katherine Po Sin Chung, Terence Kin Wah Lee

Nat Commun· November 2025

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Metabolic reprogramming in macrophages: A glutamine rescue in β-catenin mutant hepatocellular carcinoma.
Gregory Kenneth Muliawan, Terence Kin Wah Lee

Hepatology· November 2025

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Targeting cell-state plasticity driven by FOXM1/CEBPB axis disrupts developmental heterogeneity and therapeutic resistance in hepatocellular carcinoma.
Xiao-Feng Zhang, Xiao-Yu Zuo, Yun Zhu, Jia-Xu Li, Jie-Shen Xian, Terence Kin Wah Lee

J Hepatol· October 2025

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Secreted lumican from the tumor microenvironment potentiates HCC stemness and progression.
Kristy Kwan-Shuen Chan, Cheuk-Yan Wong, Kwan-Yung Au, Long-Hin Suen, Wai-Wai Yip, Terence Kin-Wah Lee

Hepatol Commun· September 2025

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Chimeric antigen receptor macrophages: a new frontier in hepatocellular carcinoma treatment.
Rainbow Wing Hei Leung, Clarence Tsun Ting Wong, Terence Kin Wah Lee

Cancer Biol Med· September 2025

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DGKH-mediated phosphatidic acid oncometabolism as a driver of self-renewal and therapy resistance in HCC.
Jia Jian Loh, Kai Yu Ng, Ianto Bosheng Huang, Mingdan Deng, Yanyan Wang, Terence Kin-Wah Lee

Hepatology· August 2025

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Polypharmacology-Driven Discovery of ZAK-I-57: A Potent Multi-Targeted Benzoxazinone Small Molecule for Hepatocellular Carcinoma Therapy.
Shakeel Ahmad Khan, Huihai Yang, Fan Ying, Chin Ngok Chu, Terence Kin Wah Lee

MedComm (2020)· August 2025

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Harnessing the Microbiome: Unveiling the Influence of the Gut Microbiota on Hepatobiliary Cancer Therapeutic Strategies.
Melody Yusong Li, Xue Qian Wu, Terence Kin Wah Lee

Clin Mol Hepatol· August 2025

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Deciphering adenosine signaling in hepatocellular carcinoma: Pathways, prognostic models, and therapeutic implications.
Huihai Yang, Martina Mang Leng Lei, Longfei Xie, Yinuo Shou, Terence Kin Wah Lee

Clin Mol Hepatol· July 2025

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AGPAT4 targeted covalent inhibitor potentiates targeted therapy to overcome cancer cell plasticity in hepatocellular carcinoma mouse models.
Kai-Yu Ng, Tin-Yan Koo, Ianto Bosheng Huang, Terence Kin-Wah Lee, Tsz-Lok Fong

Sci Transl Med· July 2025

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PROX1: A Key Regulator of Hepatocyte Identity and Tumorigenesis.
Terence Kin Wah Lee, Stephanie Ma

Cancer Res· June 2025

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Reply to correspondence on "Unveiling TRIB3: A New Mediator in MET-Driven Hepatocellular Carcinoma Progression.
Many Sze Man Chan, Terence Kin Wah Lee

Clin Mol Hepatol· June 2025

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TM4SF1 - A new immune target for treatment of hepatocellular carcinoma: Editorial on "Targeting TM4SF1 promotes tumor senescence enhancing CD8+ T cell cytotoxic function in hepatocellular carcinoma".
Chen Rui Yuan, Terence Kin Wah Lee

Clin Mol Hepatol· April 2025

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Unveiling TRIB3: A New Mediator in MET-Driven Hepatocellular Carcinoma Progression.
Many Sze Man Chan, Terence Kin Wah Lee

Clin Mol Hepatol· April 2025

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UBE2S: A novel driver of HIF-1alpha-induced metabolic reprogramming in hepatocellular carcinoma: Editorial on "UBE2S promotes glycolysis in hepatocellular carcinoma by enhancing E3 enzyme-independent polyubiquitination of VHL".
Martina Mang Leng Lei, Terence Kin Wah Lee

Clin Mol Hepatol· January 2025

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Reply to correspondence on "UBE2S: A novel driver of HIF-1alpha-induced metabolic reprogramming in hepatocellular carcinoma".
Martina Mang Leng Lei, Terence Kin Wah Lee

Clin Mol Hepatol· January 2025

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Identification of KCTD17 as a Ras stabilizer in hepatocellular carcinoma: Editorial on "KCTD17-mediated Ras stabilization promotes hepatocellular carcinoma progression".
Rainbow Wing Hei Leung, Terence Kin Wah Lee

Clin Mol Hepatol· January 2025

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Tumor-associated neutrophils attenuate the immunosensitivity of hepatocellular carcinoma.
Jia Ming Nickolas Teo, Zhulin Chen, Weixin Chen, Rachael Julia Yuenyinn Tan, Qi Cao, Terence Kin Wah Lee

J Exp Med· January 2025

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Intestinal Akkermansia muciniphila complements the efficacy of PD1 therapy in MAFLD-related hepatocellular carcinoma.
Xue Qian Wu, Fan Ying, Katherine Po Sin Chung, Carmen Oi Ning Leung, Rainbow Wing Hei Leung, Terence Kin Wah Lee

Cell Rep Med· January 2025

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The roles of cancer stem cell-derived secretory factors in shaping the immunosuppressive tumor microenvironment in hepatocellular carcinoma.
Gregory Kenneth Muliawan, Terence Kin-Wah Lee

Front Immunol· June 2024

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Covalent conjugation of AZD8055 with unsaturated fatty acids for the development of mTOR nanoblockers: increasing the therapeutic efficacy of hepatocellular carcinoma treatment.
Wing Ki Chau, Terence Kin Wah Lee

EBioMedicine· May 2024

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Targeting AXL induces tumor-intrinsic immunogenic response in tyrosine kinase inhibitor-resistant liver cancer.
Yunong Xie, Haofeng Wu, Yimiao He, Linglin Liu, Ianto Bosheng Huang, Terence Kin-Wah Lee

Cell Death Dis· February 2024

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CRISPR/Cas9 screens unravel miR-3689a-3p regulating sorafenib resistance in hepatocellular carcinoma via suppressing CCS/SOD1-dependent mitochondrial oxidative stress.
Yuanjun Lu, Yau-Tuen Chan, Junyu Wu, Zixin Feng, Hongchao Yuan, Terence Kin-Wah Lee

Drug Resist Updat· November 2023

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Broad-spectrum kinome profiling identifies CDK6 upregulation as a driver of lenvatinib resistance in hepatocellular carcinoma.
Carmen Oi Ning Leung, Yang Yang, Rainbow Wing Hei Leung, Karl Kam Hei So, Hai Jun Guo, Terence Kin Wah Lee

Nat Commun· October 2023

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