Publications by authors named "Terrance Egan"

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Contribution of S1pr1 -featured astrocyte subpopulation to cisplatin-induced neuropathic pain in male mice.
Ying Li, Silvia Squillace, Rachel Schafer, Luigino A Giancotti, Zhoumou Chen, Terrance M Egan

Pain· January 2026

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Contribution of -featured astrocyte subpopulation to cisplatin-induced neuropathic pain.
Ying Li, Silvia Squillace, Rachel Schafer, Luigino A Giancotti, Zhoumou Chen, Terrance M Egan

bioRxiv· April 2025

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Synthesis and in vitro evaluation of novel compounds and discovery of a promising iodine-125 radioligand for purinergic P2X7 receptor (P2X7R).
Lin Qiu, Jinzhi Wang, Manju Tewari, Derek T Rensing, Terrance M Egan

Bioorg Med Chem· February 2025

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Modulation of Microglial Function by ATP-Gated P2X7 Receptors: Studies in Rat, Mice and Human.
Manju Tewari, Stephanie Michalski, Terrance M Egan

Cells· January 2024

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Glioblastoma spheroid growth and chemotherapeutic responses in single and dual-stiffness hydrogels.
Joseph Bruns, Terrance Egan, Philippe Mercier, Silviya P Zustiak

Acta Biomater· June 2023

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Using Whole-Cell Electrophysiology and Patch-Clamp Photometry to Characterize P2X7 Receptor Currents.
Xin Liang, Laura Janks, Terrance M Egan

Methods Mol Biol· July 2022

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Physiology of Cultured Human Microglia Maintained in a Defined Culture Medium.
Manju Tewari, Maheen Khan, Megha Verma, Jeroen Coppens, Joanna M Kemp, Terrance M Egan

Immunohorizons· April 2021

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Ca flux through splice variants of the ATP-gated ionotropic receptor P2X7 is regulated by its cytoplasmic N terminus.
Xin Liang, Damien S K Samways, Jane Cox, Terrance M Egan

J Biol Chem· August 2019

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ATP-Gated P2X7 Receptors Require Chloride Channels To Promote Inflammation in Human Macrophages.
Laura Janks, Randy S Sprague, Terrance M Egan

J Immunol· February 2019

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A central role for P2X7 receptors in human microglia.
Laura Janks, Cristian V R Sharma, Terrance M Egan

J Neuroinflammation· November 2018

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Synthesis and in vitro characterization of a P2X7 radioligand [I]TZ6019 and its response to neuroinflammation in a mouse model of Alzheimer disease.
Hongjun Jin, Junbin Han, Derek Resing, Hui Liu, Xuyi Yue, Terrance M Egan

Eur J Pharmacol· February 2018

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P2X receptor overexpression induced by soluble oligomers of amyloid beta peptide potentiates synaptic failure and neuronal dyshomeostasis in cellular models of Alzheimer's disease.
Francisco Sáez-Orellana, María C Fuentes-Fuentes, Pamela A Godoy, Tiare Silva-Grecchi, Jessica D Panes, Terrance M Egan

Neuropharmacology· January 2018

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Pharmacologic characterizations of a P2X7 receptor-specific radioligand, [11C]GSK1482160 for neuroinflammatory response.
Junbin Han, Hui Liu, Chunling Liu, Hongjun Jin, Joel S Perlmutter, Terrance M Egan

Nucl Med Commun· May 2017

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CLIC1 null mice demonstrate a role for CLIC1 in macrophage superoxide production and tissue injury.
Barbara Ulmasov, Jonathan Bruno, Kiyoko Oshima, Yao-Wen Cheng, Stephen P Holly, Terrance M Egan

Physiol Rep· March 2017

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HSP90 Regulation of P2X7 Receptor Function Requires an Intact Cytoplasmic C-Terminus.
Keisuke Migita, Taku Ozaki, Shuji Shimoyama, Junko Yamada, Yoshikazu Nikaido, Terrance M Egan

Mol Pharmacol· August 2016

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Sorting Nexin 11 Regulates Lysosomal Degradation of Plasma Membrane TRPV3.
Caiyue Li, Wenbo Ma, Shikui Yin, Xin Liang, Xiaodong Shu, Terrance M Egan

Traffic· May 2016

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Engagement of the GABA to KCC2 signaling pathway contributes to the analgesic effects of A3AR agonists in neuropathic pain.
Amanda Ford, Annie Castonguay, Martin Cottet, Joshua W Little, Zhoumou Chen, Terrance M Egan

J Neurosci· April 2015

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Quantifying Ca2+ current and permeability in ATP-gated P2X7 receptors.
Xin Liang, Damien S K Samways, Kyle Wolf, Elizabeth A Bowles, Jennifer P Richards, Terrance M Egan

J Biol Chem· March 2015

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Imaging P2X4 receptor subcellular distribution, trafficking, and regulation using P2X4-pHluorin.
Ji Xu, Hua Chai, Konstantin Ehinger, Terrance M Egan, Rahul Srinivasan

J Gen Physiol· July 2014

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Principles and properties of ion flow in P2X receptors.
Damien S K Samways, Zhiyuan Li, Terrance M Egan

Front Cell Neurosci· March 2014

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Allosteric modulation of Ca2+ flux in ligand-gated cation channel (P2X4) by actions on lateral portals.
Damien S K Samways, Baljit S Khakh, Terrance M Egan

J Biol Chem· March 2012

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Calcium-dependent decrease in the single-channel conductance of TRPV1.
Damien S K Samways, Terrance M Egan

Pflugers Arch· November 2011

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Preferential use of unobstructed lateral portals as the access route to the pore of human ATP-gated ion channels (P2X receptors).
Damien S K Samways, Baljit S Khakh, Sébastien Dutertre, Terrance M Egan

Proc Natl Acad Sci U S A· August 2011

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Pannexin 1 is the conduit for low oxygen tension-induced ATP release from human erythrocytes.
Meera Sridharan, Shaquria P Adderley, Elizabeth A Bowles, Terrance M Egan, Alan H Stephenson

Am J Physiol Heart Circ Physiol· October 2010

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P2X4 receptors in activated C8-B4 cells of cerebellar microglial origin.
Estelle Toulme, Angie Garcia, Damien Samways, Terrance M Egan, Monica J Carson

J Gen Physiol· April 2010

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