Publications by authors named "Terry A Beerman"

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The radiomimetic enediyne, 20'-deschloro-C-1027 induces inter-strand DNA crosslinks in hypoxic cells and overcomes cytotoxic radioresistance.
Terry A Beerman, Loretta S Gawron, Ben Shen, Daniel R Kennedy

DNA Repair (Amst)· September 2014

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DNA damage by C1027 involves hydrogen atom abstraction and addition to nucleobases.
Joanna Maria N San Pedro, Terry A Beerman, Marc M Greenberg

Bioorg Med Chem· August 2012

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C-1027, a radiomimetic enediyne anticancer drug, preferentially targets hypoxic cells.
Terry A Beerman, Loretta S Gawron, Seulkih Shin, Ben Shen, Mary M McHugh

Cancer Res· January 2009

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Designer enediynes generate DNA breaks, interstrand cross-links, or both, with concomitant changes in the regulation of DNA damage responses.
Daniel R Kennedy, Jianhua Ju, Ben Shen, Terry A Beerman

Proc Natl Acad Sci U S A· November 2007

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Single chemical modifications of the C-1027 enediyne core, a radiomimetic antitumor drug, affect both drug potency and the role of ataxia-telangiectasia mutated in cellular responses to DNA double-strand breaks.
Daniel R Kennedy, Loretta S Gawron, Jianhua Ju, Wen Liu, Ben Shen, Terry A Beerman

Cancer Res· January 2007

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Inhibition of RecBCD enzyme by antineoplastic DNA alkylating agents.
Barbara Dziegielewska, Terry A Beerman, Piero R Bianco

J Mol Biol· September 2006

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The radiomimetic enediyne C-1027 induces unusual DNA damage responses to double-strand breaks.
Daniel R Kennedy, Terry A Beerman

Biochemistry· March 2006

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Hedamycin, a DNA alkylator, induces (gamma)H2AX and chromosome aberrations: involvement of phosphatidylinositol 3-kinase-related kinases and DNA replication fork movement.
Lan Chun Tu, Sei Ichi Matsui, Terry A Beerman

Mol Cancer Ther· August 2005

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The antitumor enediyne C-1027 alters cell cycle progression and induces chromosomal aberrations and telomere dysfunction.
Mary M McHugh, Loretta S Gawron, Sei-Ichi Matsui, Terry A Beerman

Cancer Res· June 2005

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DNA damage effects of a polyamide-CBI conjugate in SV40 virions.
Brian J Philips, Aileen Y Chang, Peter B Dervan, Terry A Beerman

Mol Pharmacol· March 2005

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SV40 DNA replication inhibition by the monofunctional DNA alkylator Et743.
Barbara Dziegielewska, David Kowalski, Terry A Beerman

Biochemistry· November 2004

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DNA damage responses triggered by a highly cytotoxic monofunctional DNA alkylator, hedamycin, a pluramycin antitumor antibiotic.
Lan Chun Tu, Thomas Melendy, Terry A Beerman

Mol Cancer Ther· May 2004

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DNA crosslinking and biological activity of a hairpin polyamide-chlorambucil conjugate.
Yong-Dong Wang, Jaroslaw Dziegielewski, Nicholas R Wurtz, Barbara Dziegielewska, Peter B Dervan, Terry A Beerman

Nucleic Acids Res· February 2003

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Induction of DNA damage responses by adozelesin is S phase-specific and dependent on active replication forks.
Jen-Sing Liu, Shu-Ru Kuo, Terry A Beerman, Thomas Melendy

Mol Cancer Ther· January 2003

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Cell-free and cellular activities of a DNA sequence selective hairpin polyamide-CBI conjugate.
Yong-Dong Wang, Jaroslaw Dziegielewski, Aileen Y Chang, Peter B Dervan, Terry A Beerman

J Biol Chem· November 2002

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Cellular uptake of N-methylpyrrole/N-methylimidazole polyamide-dye conjugates.
Jason M Belitsky, Stephanie J Leslie, Paramjit S Arora, Terry A Beerman, Peter B Dervan

Bioorg Med Chem· October 2002

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Cellular responses to the DNA strand-scission enediyne C-1027 can be independent of ATM, ATR, and DNA-PK kinases.
Jaroslaw Dziegielewski, Terry A Beerman

J Biol Chem· June 2002

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Inhibiting transcription factor/DNA complexes using fluorescent microgonotropens (FMGTs).
Christine M White, Alexander L Satz, Loretta S Gawron, Thomas C Bruice, Terry A Beerman

Biochim Biophys Acta· February 2002

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