Publications by authors named "Thaddeus Wadas"

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Monitoring Response to Combinatorial Immunotherapies by Tracking both T Cells and Natural Killer Cells via ImmunoPET-Raman Multimodal Gold Nanostars.
Gabriel P Cutshaw, Siddhant Kothadiya, Saji Uthaman, Darpan N Pandya, Xiaona Wen, Thaddeus J Wadas

ACS Appl Mater Interfaces· October 2025

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The Evaluation of (1,4,7,10)-α,α',α″,α‴-Tetramethyl-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic Acid (DOTMA) as a Chelator for Zirconium-89.
Darpan N Pandya, Pere Miro, Michael A Sinnwell, George B Crull, Thaddeus J Wadas

Molecules· October 2025

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Protein-based Radiopharmaceuticals that target fibroblast activation protein alpha: a review of current progress.
Abdelrahman Homedan, Darpan N Pandya, Nicholas J Schnicker, Thaddeus J Wadas

EJNMMI Radiopharm Chem· June 2025

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Cryo-electron microscopy reveals a single domain antibody with a unique binding epitope on fibroblast activation protein alpha.
Zhen Xu, Akesh Sinha, Darpan N Pandya, Nicholas J Schnicker, Thaddeus J Wadas

RSC Chem Biol· May 2025

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Cryo-electron microscopy reveals a single domain antibody with a unique binding epitope on fibroblast activation protein alpha.
Zhen Xu, Akesh Sinha, Darpan N Pandya, Nicholas J Schnicker, Thaddeus J Wadas

bioRxiv· October 2024

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Gallium Uncouples Iron Metabolism to Enhance Glioblastoma Radiosensitivity.
Stephenson B Owusu, Amira Zaher, Stephen Ahenkorah, Darpah N Pandya, Thaddeus J Wadas

Int J Mol Sci· September 2024

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A pipeline for facile cloning of antibody Fv domains and their expression, purification, and characterization as recombinant His-tagged IgGs.
Akesh Sinha, Jinha M Park, Naveed Gulzar, Darpan N Pandya, Thaddeus J Wadas

bioRxiv· February 2024

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Transgenic ferret models define pulmonary ionocyte diversity and function.
Feng Yuan, Grace N Gasser, Evan Lemire, Daniel T Montoro, Karthik Jagadeesh, Thaddeus J Wadas

Nature· September 2023

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Theranostics through Utilizing Cherenkov Radiation of Radioisotope Zr-89 with a Nanocomposite Combination of TiO and MnO.
Pyeong Seok Choi, Jun Young Lee, Jung Ho Chae, Thaddeus Wadas, Zhen Cheng

ACS Appl Mater Interfaces· January 2023

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Pharmacological ascorbate as a novel therapeutic strategy to enhance cancer immunotherapy.
Amira Zaher, Laura M Stephens, Ann M Miller, Stacey M Hartwig, Jeffrey M Stolwijk, Thaddeus J Wadas

Front Immunol· September 2022

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Radiopharmaceutical Quality Control Considerations for Accelerator-Produced Actinium Therapies.
Diane S Abou, Patrick Zerkel, James Robben, Mark McLaughlin, Tim Hazlehurst, Thaddeus J Wadas

Cancer Biother Radiopharm· June 2022

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Establishment of Novel Neuroendocrine Carcinoma Patient-Derived Xenograft Models for Receptor Peptide-Targeted Therapy.
Catherine G Tran, Luis C Borbon, Jacqueline L Mudd, Ellen Abusada, Solmaz AghaAmiri, Thaddeus J Wadas

Cancers (Basel)· April 2022

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Preclinical evaluation of [Ac]Ac-DOTA-TATE for treatment of lung neuroendocrine neoplasms.
Narges K Tafreshi, Darpan N Pandya, Christopher J Tichacek, Mikalai M Budzevich, Zhen Wang, Thaddeus J Wadas

Eur J Nucl Med Mol Imaging· October 2021

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Lipophilicity Determines Routes of Uptake and Clearance, and Toxicity of an Alpha-Particle-Emitting Peptide Receptor Radiotherapy.
Narges K Tafreshi, HyunJoo Kil, Darpan N Pandya, Christopher J Tichacek, Michael L Doligalski, Thaddeus J Wadas

ACS Pharmacol Transl Sci· April 2021

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Progress in Targeted Alpha-Particle-Emitting Radiopharmaceuticals as Treatments for Prostate Cancer Patients with Bone Metastases.
Chirayu M Patel, Thaddeus J Wadas, Yusuke Shiozawa

Molecules· April 2021

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Imaging and dosimetric characteristics of Cu.
Michael J Merrick, David A Rotsch, Ashok Tiwari, Jerry Nolen, Thomas Brossard, Thaddeus J Wadas

Phys Med Biol· January 2021

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Polyazamacrocycle Ligands Facilitate Zr Radiochemistry and Yield Zr Complexes with Remarkable Stability.
Darpan N Pandya, Kelly E Henry, Cynthia S Day, Stephen A Graves, Veronica L Nagle, Thaddeus J Wadas

Inorg Chem· December 2020

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Biodistribution and Multicompartment Pharmacokinetic Analysis of a Targeted α Particle Therapy.
Christopher J Tichacek, Narges K Tafreshi, HyunJoo Kil, Robert W Engelman, Michael L Doligalski, Thaddeus J Wadas

Mol Pharm· November 2020

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Imaging of Fibroblast Activation Protein Alpha Expression in a Preclinical Mouse Model of Glioma Using Positron Emission Tomography.
Darpan N Pandya, Akesh Sinha, Hong Yuan, Lysette Mutkus, Kristina Stumpf, Thaddeus J Wadas

Molecules· August 2020

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Development of Targeted Alpha Particle Therapy for Solid Tumors.
Narges K Tafreshi, Michael L Doligalski, Christopher J Tichacek, Darpan N Pandya, Mikalai M Budzevich, Thaddeus J Wadas

Molecules· November 2019

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A Monte Carlo Method for Determining the Response Relationship between Two Commonly Used Detectors to Indirectly Measure Alpha Particle Radiation Activity.
Christopher J Tichacek, Mikalai M Budzevich, Thaddeus J Wadas, David L Morse, Eduardo G Moros

Molecules· September 2019

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Melanocortin 1 Receptor-Targeted α-Particle Therapy for Metastatic Uveal Melanoma.
Narges K Tafreshi, Christopher J Tichacek, Darpan N Pandya, Michael L Doligalski, Mikalai M Budzevich, Thaddeus J Wadas

J Nucl Med· August 2019

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Zr-Chloride Can Be Used for Immuno-PET Radiochemistry Without Loss of Antigen Reactivity In Vivo.
Darpan N Pandya, Nikunj B Bhatt, Frankis Almaguel, Stephanie Rideout-Danner, Howard D Gage, Thaddeus J Wadas

J Nucl Med· May 2019

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Practical Guidelines for Cerenkov Luminescence Imaging with Clinically Relevant Isotopes.
Nikunj B Bhatt, Darpan N Pandya, William A Dezarn, Frank C Marini, Dawen Zhao, Thaddeus J Wadas

Methods Mol Biol· February 2019

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A comprehensively revised strategy that improves the specific activity and long-term stability of clinically relevant Zr-immuno-PET agents.
Nikunj B Bhatt, Darpan N Pandya, Stephanie Rideout-Danner, Howard D Gage, Frank C Marini, Thaddeus J Wadas

Dalton Trans· October 2018

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