Publications by authors named "Thomas A Steitz"

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RNA stabilization by a poly(A) tail 3'-end binding pocket and other modes of poly(A)-RNA interaction.
Seyed-Fakhreddin Torabi, Anand T Vaidya, Kazimierz T Tycowski, Suzanne J DeGregorio, Jimin Wang, Thomas A Steitz, Joan A Steitz

Science· February 2021

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Structural Insights into Transcription Initiation from RNA Synthesis to Transitioning into Elongation.
Yuhong Zuo, Swastik De, Yingang Feng, Thomas A Steitz

iScience· September 2020

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Molecular dynamics analysis of Mg -dependent cleavage of a pistol ribozyme reveals a fail-safe secondary ion for catalysis.
Newlyn N Joseph, Raktim N Roy, Thomas A Steitz

J Comput Chem· May 2020

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Crystal structure of the C-terminal domain of DENR.
Ivan B Lomakin, Swastik De, Jimin Wang, Aditi N Borkar, Thomas A Steitz

Comput Struct Biotechnol J· March 2020

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Identification of Dihydrofuro[3,4- d]pyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors with Promising Antiviral Activities and Desirable Physicochemical Properties.
Dongwei Kang, Heng Zhang, Zhao Wang, Tong Zhao, Tiziana Ginex, Thomas A Steitz

J Med Chem· February 2019

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Crystal structure of the DENR-MCT-1 complex revealed zinc-binding site essential for heterodimer formation.
Ivan B Lomakin, Sergey E Dmitriev, Thomas A Steitz

Proc Natl Acad Sci U S A· January 2019

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Structural basis for potent and broad inhibition of HIV-1 RT by thiophene[3,2-]pyrimidine non-nucleoside inhibitors.
Yang Yang, Dongwei Kang, Laura A Nguyen, Zachary B Smithline, Christophe Pannecouque, Thomas A Steitz

Elife· July 2018

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Ribosome-Targeting Antibiotics: Modes of Action, Mechanisms of Resistance, and Implications for Drug Design.
Jinzhong Lin, Dejian Zhou, Thomas A Steitz, Yury S Polikanov, Matthieu G Gagnon

Annu Rev Biochem· June 2018

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Structural basis of bacterial transcription activation.
Bin Liu, Chuan Hong, Rick K Huang, Zhiheng Yu, Thomas A Steitz

Science· November 2017

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Crystal Structure of the C-terminal Domain of Human eIF2D and Its Implications on Eukaryotic Translation Initiation.
Anand T Vaidya, Ivan B Lomakin, Newlyn N Joseph, Sergey E Dmitriev, Thomas A Steitz

J Mol Biol· September 2017

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Crystal Structure of the Human Ribosome in Complex with DENR-MCT-1.
Ivan B Lomakin, Elena A Stolboushkina, Anand T Vaidya, Chenguang Zhao, Maria B Garber, Thomas A Steitz

Cell Rep· July 2017

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Perspectives on the ribosome.
Thomas A Steitz, Peter B Moore

Philos Trans R Soc Lond B Biol Sci· March 2017

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A structure-based kinetic model of transcription.
Yuhong Zuo, Thomas A Steitz

Transcription· January 2017

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Structural insights into NusG regulating transcription elongation.
Bin Liu, Thomas A Steitz

Nucleic Acids Res· January 2017

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Crystal structure of Pistol, a class of self-cleaving ribozyme.
Laura A Nguyen, Jimin Wang, Thomas A Steitz

Proc Natl Acad Sci U S A· January 2017

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Insights into RNA binding by the anticancer drug cisplatin from the crystal structure of cisplatin-modified ribosome.
Sergey V Melnikov, Dieter Söll, Thomas A Steitz, Yury S Polikanov

Nucleic Acids Res· June 2016

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Elongation factor 4 remodels the A-site tRNA on the ribosome.
Matthieu G Gagnon, Jinzhong Lin, Thomas A Steitz

Proc Natl Acad Sci U S A· May 2016

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Structures of E. coli σS-transcription initiation complexes provide new insights into polymerase mechanism.
Bin Liu, Yuhong Zuo, Thomas A Steitz

Proc Natl Acad Sci U S A· April 2016

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Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition.
Matthieu G Gagnon, Raktim N Roy, Ivan B Lomakin, Tanja Florin, Alexander S Mankin, Thomas A Steitz

Nucleic Acids Res· March 2016

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Antimicrobial peptides targeting bacterial ribosome.
Ivan B Lomakin, Matthieu G Gagnon, Thomas A Steitz

Oncotarget· August 2015

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Crystal Structure of Human Profilaggrin S100 Domain and Identification of Target Proteins Annexin II, Stratifin, and HSP27.
Christopher G Bunick, Richard B Presland, Owen T Lawrence, David J Pearton, Leonard M Milstone, Thomas A Steitz

J Invest Dermatol· July 2015

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The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin.
Raktim N Roy, Ivan B Lomakin, Matthieu G Gagnon, Thomas A Steitz

Nat Struct Mol Biol· June 2015

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Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A.
Yury S Polikanov, Agata L Starosta, Manuel F Juette, Roger B Altman, Daniel S Terry, Thomas A Steitz

Mol Cell· June 2015

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Crystal structures of the E. coli transcription initiation complexes with a complete bubble.
Yuhong Zuo, Thomas A Steitz

Mol Cell· May 2015

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Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly.
Yury S Polikanov, Sergey V Melnikov, Dieter Söll, Thomas A Steitz

Nat Struct Mol Biol· April 2015

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