Publications by authors named "Thomas Ahearn"

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Integrating multi-ancestry genomic and proteomic data to identify blood risk biomarkers and target proteins for breast cancer genetic risk loci.
Guochong Jia, Jie Ping, Ran Tao, Jirong Long, Lili Liu, Thomas Ahearn

Int J Cancer· November 2025

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Genetic and Cellular Architecture of Breast Cancer Risk in Multi-Ancestry Studies of 159,297 Cases and 212,102 Controls.
James L Li, Maria Zanti, Jacob Williams, Om Jahagirdar, Guochong Jia, Thomas U Ahearn

medRxiv· November 2025

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Threshold-Based Overlap of Breast Cancer High-Risk Classification Using Family History, Polygenic Risk Scores, and Traditional Risk Models in 180,398 Women.
Peh Joo Ho, Christine Kim Yan Loo, Ryan Jak Yang Lim, Meng Huang Goh, Mustapha Abubakar, Thomas U Ahearn

Cancers (Basel)· November 2025

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Breast Cancer Incidence Rates in Ghanaian and US Black Women From 2013 Through 2015.
Brittny C Davis Lynn, Jonine D Figueroa, Dennis Laryea, Fred Kwame Awittor, Naomi O Ohene Oti, Thomas Ahearn

JAMA Netw Open· October 2025

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Large-scale meta-analysis and precision functional assays identify FANCM regions in which PTVs confer different risks for ER-negative and triple-negative breast cancer.
Amandine Billaud, Gisella Figlioli, Clémence Mooser, Irene Casamassima, Violette Azzoni, Thomas U Ahearn

Breast· October 2025

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Unraveling the role of stromal disruption in aggressive breast cancer etiology and outcomes.
Mustapha Abubakar, Máire A Duggan, Shaoqi Fan, Ruth M Pfeiffer, Scott Lawrence, Thomas U Ahearn

J Natl Cancer Inst· August 2025

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Multi-Ancestry Transcriptome-wide Association Studies Uncover New Insights into Breast Cancer Genetics and Biology.
Jie Ping, Guochong Jia, Qiuyin Cai, Xingyi Guo, Jifeng Wang, Thomas Ahearn

medRxiv· August 2025

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Exogenous Hormones, Tumor Intrinsic Subtypes, and Breast Cancer.
Charlotte Le Cornet, Audrey Y Jung, Sabine Behrens, Pooja Middha, Thérèse Truong, Thomas U Ahearn

JAMA Netw Open· July 2025

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Analysis of more than 400,000 women provides case-control evidence for BRCA1 and BRCA2 variant classification.
Maria Zanti, Denise G O'Mahony, Michael T Parsons, Leila Dorling, Joe Dennis, Thomas U Ahearn

Nat Commun· May 2025

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Contribution of Prediagnostic Host Factors to Shaping the Stromal Microenvironment of Breast Cancer among Sub-Saharan African Women.
Mustapha Abubakar, Thomas U Ahearn, Maire A Duggan, Scott Lawrence, Ernest K Adjei

Cancer Epidemiol Biomarkers Prev· April 2025

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Polygenic risk scores stratify breast cancer risk among women with benign breast disease.
Mark E Sherman, Stacey J Winham, Robert A Vierkant, Bryan M McCauley, Christopher G Scott, Thomas Ahearn

J Natl Cancer Inst· March 2025

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Overlap of high-risk individuals across family history, genetic & non-genetic breast cancer risk models: Analysis of 180,398 women from European & Asian ancestries.
Peh Joo Ho, Christine Kim Yan Loo, Meng Huang Goh, Mustapha Abubakar, Thomas U Ahearn

medRxiv· March 2025

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Refining breast cancer genetic risk and biology through multi-ancestry fine-mapping analyses of 192 risk regions.
Guochong Jia, Zhishan Chen, Jie Ping, Qiuyin Cai, Ran Tao, Thomas Ahearn

Nat Genet· January 2025

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Risk factors for breast cancer subtypes by race and ethnicity: a scoping review.
Amber N Hurson, Thomas U Ahearn, Hela Koka, Brittany D Jenkins, Alexandra R Harris

J Natl Cancer Inst· December 2024

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Erratum: "Moving toward findable, accessible, interoperable, reusable practices in epidemiologic research".
Montserrat García-Closas, Thomas U Ahearn, Mia M Gaudet, Amber N Hurson, Jeya Balaji Balasubramanian

Am J Epidemiol· December 2024

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Polygenic score distribution differences across European ancestry populations: implications for breast cancer risk prediction.
Kristia Yiangou, Nasim Mavaddat, Joe Dennis, Maria Zanti, Qin Wang, Thomas U Ahearn

Breast Cancer Res· December 2024

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Co-observation of germline pathogenic variants in breast cancer predisposition genes: Results from analysis of the BRIDGES sequencing dataset.
Aimee L Davidson, Kyriaki Michailidou, Michael T Parsons, Cristina Fortuno, Manjeet K Bolla, Thomas U Ahearn

Am J Hum Genet· September 2024

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Analysis of more than 400,000 women provides case-control evidence for and variant classification.
Maria Zanti, Denise G O'Mahony, Michael T Parsons, Leila Dorling, Joe Dennis, Thomas U Ahearn

medRxiv· September 2024

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Publisher Correction: Understanding the genetic complexity of puberty timing across the allele frequency spectrum.
Katherine A Kentistou, Lena R Kaisinger, Stasa Stankovic, Marc Vaudel, Edson Mendes de Oliveira, Thomas U Ahearn

Nat Genet· August 2024

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Disentangling the relationships of body mass index and circulating sex hormone concentrations in mammographic density using Mendelian randomization.
Cameron B Haas, Hongjie Chen, Tabitha Harrison, Shaoqi Fan, Manuela Gago-Dominguez, Thomas Ahearn

Breast Cancer Res Treat· July 2024

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Wasm-iCARE: a portable and privacy-preserving web module to build, validate, and apply absolute risk models.
Jeya Balaji Balasubramanian, Parichoy Pal Choudhury, Srijon Mukhopadhyay, Thomas Ahearn, Nilanjan Chatterjee

JAMIA Open· July 2024

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Understanding the genetic complexity of puberty timing across the allele frequency spectrum.
Katherine A Kentistou, Lena R Kaisinger, Stasa Stankovic, Marc Vaudel, Edson Mendes de Oliveira, Thomas U Ahearn

Nat Genet· July 2024

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Using genome and transcriptome data from African-ancestry female participants to identify putative breast cancer susceptibility genes.
Jie Ping, Guochong Jia, Qiuyin Cai, Xingyi Guo, Ran Tao, Thomas Ahearn

Nat Commun· May 2024

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Genome-wide association analyses of breast cancer in women of African ancestry identify new susceptibility loci and improve risk prediction.
Guochong Jia, Jie Ping, Xingyi Guo, Yaohua Yang, Ran Tao, Thomas Ahearn

Nat Genet· May 2024

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Risk factors for breast cancer subtypes by race and ethnicity: A scoping review of the literature.
Amber N Hurson, Thomas U Ahearn, Hela Koka, Brittany D Jenkins, Alexandra R Harris

medRxiv· March 2024

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