Publications by authors named "Thomas Ashhurst"

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The changing immune landscape of innate-like T cells and other innate cells throughout life.
Marziyeh Taheri, Christopher Menne, Jeremy Anderson, Louis Perriman, Shuo Li, Thomas M Ashhurst

Immunol Cell Biol· December 2025

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High-dimensional flow cytometry reveals lymphocyte subset populations predictive of chronic lung allograft dysfunction.
Rohia Farighi, Steven Hiho, Thomas Ashhurst, Emily Sj Edwards, Lucy Sullivan

Clin Transl Immunology· September 2025

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Spatial mapping of the HCC landscape identifies unique intratumoral perivascular-immune neighborhoods.
Felix Marsh-Wakefield, Cositha Santhakumar, Angela L Ferguson, Thomas M Ashhurst, Joo-Shik Shin

Hepatol Commun· November 2024

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A unique human cord blood CD8CD45RACD27CD161 T-cell subset identified by flow cytometric data analysis using Seurat.
Julen Gabirel Araneta Reyes, Duan Ni, Brigitte Santner-Nanan, Gabriela Veronica Pinget, Lucie Kraftova, Thomas Myles Ashhurst

Immunology· September 2024

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T cell activation markers CD38 and HLA-DR indicative of non-seroconversion in anti-CD20-treated patients with multiple sclerosis following SARS-CoV-2 mRNA vaccination.
Niels J M Verstegen, Ruth R Hagen, Christine Kreher, Lisan H Kuijper, Jet van den Dijssel, Thomas Ashhurst

J Neurol Neurosurg Psychiatry· August 2024

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A single-dose intranasal live-attenuated codon deoptimized vaccine provides broad protection against SARS-CoV-2 and its variants.
Xiang Liu, Wern Hann Ng, Eva Zusinaite, Joseph Freitas, Adam Taylor, Thomas M Ashhurst

Nat Commun· August 2024

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Faecal microbial transfer and complex carbohydrates mediate protection against COPD.
Kurtis F Budden, Shakti D Shukla, Kate L Bowerman, Annalicia Vaughan, Shaan L Gellatly, Thomas Ashhurst

Gut· April 2024

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SuperCellCyto: enabling efficient analysis of large scale cytometry datasets.
Givanna H Putri, George Howitt, Felix Marsh-Wakefield, Thomas M Ashhurst, Belinda Phipson

Genome Biol· April 2024

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CD8 T Cells Mediate Lethal Lung Pathology in the Absence of PD-L1 and Type I Interferon Signalling following LCMV Infection.
Alanna G Spiteri, Tamara Suprunenko, Erin Cutts, Andrew Suen, Thomas M Ashhurst

Viruses· March 2024

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Clodronate is not protective in lethal viral encephalitis despite substantially reducing inflammatory monocyte infiltration in the CNS.
Alanna G Spiteri, Caryn van Vreden, Thomas M Ashhurst, Paula Niewold, Nicholas J C King

Front Immunol· August 2023

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A unique cytotoxic CD4 T cell-signature defines critical COVID-19.
Sarah Baird, Caroline L Ashley, Felix Marsh-Wakefield, Sibel Alca, Thomas M Ashhurst

Clin Transl Immunology· August 2023

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CD4 T cell calibration of antigen-presenting cells optimizes antiviral CD8 T cell immunity.
Elise Gressier, Jonas Schulte-Schrepping, Lev Petrov, Sophia Brumhard, Paula Stubbemann, Thomas Ashhurst

Nat Immunol· June 2023

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Circulating effector γδ T cell populations are associated with acute coronavirus disease 19 in unvaccinated individuals.
Anouk von Borstel, Thi Ho Nguyen, Louise C Rowntree, Thomas M Ashhurst, Lilith F Allen

Immunol Cell Biol· April 2023

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TrackSOM: Mapping immune response dynamics through clustering of time-course cytometry data.
Givanna H Putri, Jonathan Chung, Davis N Edwards, Felix Marsh-Wakefield, Irena Koprinska, Thomas M Ashhurst

Cytometry A· January 2023

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A high-dimensional cytometry atlas of peripheral blood over the human life span.
Sedigheh Jalali, Christopher M Harpur, Adam T Piers, Maria Auladell, Louis Perriman, Thomas M Ashhurst

Immunol Cell Biol· November 2022

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Peripheral B-cell dysregulation is associated with relapse after long-term quiescence in patients with multiple sclerosis.
Felix Marsh-Wakefield, Pierre Juillard, Thomas M Ashhurst, Annette Juillard, Diana Shinko

Immunol Cell Biol· July 2022

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Immune dynamics in SARS-CoV-2 experienced immunosuppressed rheumatoid arthritis or multiple sclerosis patients vaccinated with mRNA-1273.
Niels J M Verstegen, Ruth R Hagen, Jet van den Dijssel, Lisan H Kuijper, Christine Kreher, Thomas Ashhurst

Elife· July 2022

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SARS-CoV-2 infection results in immune responses in the respiratory tract and peripheral blood that suggest mechanisms of disease severity.
Wuji Zhang, Brendon Y Chua, Kevin J Selva, Lukasz Kedzierski, Thomas M Ashhurst

Nat Commun· May 2022

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The cytokines interleukin-6 and interferon-α induce distinct microglia phenotypes.
Phillip K West, Andrew N McCorkindale, Boris Guennewig, Thomas M Ashhurst, Barney Viengkhou

J Neuroinflammation· April 2022

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Integration, exploration, and analysis of high-dimensional single-cell cytometry data using Spectre.
Thomas Myles Ashhurst, Felix Marsh-Wakefield, Givanna Haryono Putri, Alanna Gabrielle Spiteri, Diana Shinko

Cytometry A· March 2022

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An updated guide for the perplexed: cytometry in the high-dimensional era.
Thomas Liechti, Lukas M Weber, Thomas M Ashhurst, Natalie Stanley, Martin Prlic

Nat Immunol· October 2021

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Making the most of high-dimensional cytometry data.
Felix Md Marsh-Wakefield, Andrew J Mitchell, Samuel E Norton, Thomas Myles Ashhurst, Julia Kh Leman

Immunol Cell Biol· August 2021

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Immune responses in COVID-19 respiratory tract and blood reveal mechanisms of disease severity.
Wuji Zhang, Brendon Chua, Kevin Selva, Lukasz Kedzierski, Thomas Ashhurst

Res Sq· August 2021

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High-parameter cytometry unmasks microglial cell spatio-temporal response kinetics in severe neuroinflammatory disease.
Alanna G Spiteri, Rachel L Terry, Claire L Wishart, Thomas M Ashhurst, Iain L Campbell

J Neuroinflammation· July 2021

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Integrated immune dynamics define correlates of COVID-19 severity and antibody responses.
Marios Koutsakos, Louise C Rowntree, Luca Hensen, Brendon Y Chua, Carolien E van de Sandt, Thomas M Ashhurst

Cell Rep Med· March 2021

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