Publications by authors named "Thomas C Boothby"

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OsmoFold: A high-throughput tool for predicting the impact of osmolytes on protein structure.
Vincent Nicholson, Sujina Maharjan, Shahar Sukenik, Thomas C Boothby

Biophys J· November 2025

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A phase transition modulates the protective function of a tardigrade disordered protein during desiccation.
Kenny Nguyen, Sourav Biswas, Shraddha Kc, Annie Walgren, Vincent Nicholson, Thomas C Boothby

Protein Sci· October 2025

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Protein surface chemistry encodes an adaptive tolerance to desiccation.
Paulette Sofía Romero-Pérez, Haley M Moran, David P Cordone, Azeem Horani, Alexander Truong, Thomas C Boothby

Cell Syst· October 2025

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A Group 6 LEA Protein Plays Key Roles in Tolerance to Water Deficit, and in Maintaining the Glassy State and Longevity of Seeds.
Inti A Arroyo-Mosso, H Nicholay Diaz-Ardila, Alejandro Garciarrubio, U G V S S Kumara, David F Rendón-Luna, Thomas C Boothby

Plant Cell Environ· September 2025

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Diversity in the protective role(s) of the conserved motif 1 from tardigrade cytoplasmic-abundant heat-soluble proteins during drying.
Sourav Biswas, Thomas C Boothby

Protein Sci· March 2025

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LEA_4 motifs function alone and in conjunction with synergistic cosolutes to protect a labile enzyme during desiccation.
Vincent Nicholson, Kenny Nguyen, Edith Gollub, Mary McCoy, Feng Yu, Thomas C Boothby

Protein Sci· February 2025

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Osmolyte-IDP interactions during desiccation.
Vincent Nicholson, Emma Meese, Thomas C Boothby

Prog Mol Biol Transl Sci· February 2025

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Disordered proteins interact with the chemical environment to tune their protective function during drying.
Shraddha Kc, Kenny H Nguyen, Vincent Nicholson, Annie Walgren, Tony Trent, Thomas C Boothby

Elife· November 2024

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Protein surface chemistry encodes an adaptive tolerance to desiccation.
Paulette Sofía Romero-Pérez, Haley M Moran, Azeem Horani, Alexander Truong, Edgar Manriquez-Sandoval, Thomas C Boothby

bioRxiv· October 2024

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An evaluation of thermal tolerance in six tardigrade species in an active and dry state.
Jacob Loeffelholz, Emma Meese, Ilaria Giovannini, Karsyn Ullibarri, Sogol Momeni, Thomas C Boothby

Biol Open· October 2024

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Disordered proteins interact with the chemical environment to tune their protective function during drying.
Shraddha Kc, Kenny H Nguyen, Vincent Nicholson, Annie Walgren, Tony Trent, Thomas C Boothby

bioRxiv· August 2024

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Surviving extreme radiation.
Chaitra Shree Udugere Shivakumara Swamy, Thomas C Boothby

Elife· July 2024

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Helicity of a tardigrade disordered protein contributes to its protective function during desiccation.
Sourav Biswas, Edith Gollub, Feng Yu, Garrett Ginell, Alex Holehouse, Thomas C Boothby

Protein Sci· February 2024

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Water content, transition temperature and fragility influence protection and anhydrobiotic capacity.
John F Ramirez, U G V S S Kumara, Navamoney Arulsamy, Thomas C Boothby

BBA Adv· January 2024

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Water content, transition temperature and fragility influence protection and anhydrobiotic capacity.
John F Ramirez, U G V S S Kumara, Navamoney Arulsamy, Thomas C Boothby

bioRxiv· November 2023

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Editorial: Physiology of invertebrate sensing in extreme conditions and hostile environment.
Michele Cesari, Chiara Boschetti, Thomas C Boothby

Front Physiol· November 2023

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The tardigrade protein CAHS D interacts with, but does not retain, water in hydrated and desiccated systems.
Silvia Sanchez-Martinez, John F Ramirez, Emma K Meese, Charles A Childs, Thomas C Boothby

Sci Rep· June 2023

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Natural and engineered mediators of desiccation tolerance stabilize Human Blood Clotting Factor VIII in a dry state.
Maxwell H Packebush, Silvia Sanchez-Martinez, Sourav Biswas, Shraddha Kc, Kenny H Nguyen, Thomas C Boothby

Sci Rep· March 2023

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National Blood Foundation 2021 Research and Development summit: Discovery, innovation, and challenges in advancing blood and biotherapies.
Jerry A Holmberg, Stephen M Henry, Thierry Burnouf, Dana Devine, Susanne Marschner, Thomas C Boothby

Transfusion· November 2022

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Trehalose and tardigrade CAHS proteins work synergistically to promote desiccation tolerance.
Kenny Nguyen, Shraddha Kc, Tyler Gonzalez, Hugo Tapia, Thomas C Boothby

Commun Biol· October 2022

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Production of reactive oxygen species and involvement of bioprotectants during anhydrobiosis in the tardigrade Paramacrobiotus spatialis.
Ilaria Giovannini, Thomas C Boothby, Michele Cesari, Bob Goldstein, Roberto Guidetti

Sci Rep· February 2022

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Water content influences the vitrified properties of CAHS proteins.
Thomas C Boothby

Mol Cell· February 2021

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The biology of tardigrade disordered proteins in extreme stress tolerance.
Cherie Hesgrove, Thomas C Boothby

Cell Commun Signal· November 2020

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Membrane and lipid metabolism plays an important role in desiccation resistance in the yeast Saccharomyces cerevisiae.
Qun Ren, Rebecca Brenner, Thomas C Boothby, Zhaojie Zhang

BMC Microbiol· November 2020

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Mechanisms and evolution of resistance to environmental extremes in animals.
Thomas C Boothby

Evodevo· November 2019

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