Publications by authors named "Thomas C Wirth"

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A preclinical model for the identification of therapeutically active transgenes in local cancer immunotherapy.
Arne Menze, Dmitrij Ostroumov, Hans Heinrich Wedemeyer, Valery Volk, Friedrich Feuerhake, Thomas Christian Wirth

Oncoimmunology· December 2025

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Ga-FAPI-46 PET/CT in Primary Sclerosing Cholangitis and Suspected Cholangiocarcinoma.
Desiree Weiberg, Laura M Wilhelm, Tim Felgenhauer, Tobias Ross, Heiner Wedemeyer, Thomas C Wirth

J Nucl Med· November 2025

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Chemo- and Radiotherapy of Gastrointestinal Tumors during Pregnancy.
Thomas Christian Wirth, Anna Saborowski, Elna Kuehnle, Mirko Fischer, Eva Bültmann

Visc Med· April 2025

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Sequential STING and CD40 agonism drives massive expansion of tumor-specific T cells in liposomal peptide vaccines.
Dmitrij Ostroumov, Naomi Benne, Fernando Lozano Vigario, Oscar Escalona-Rayo, Ksenia Dodz, Thomas Christian Wirth

Cell Mol Immunol· February 2025

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Oncolytic viruses expressing MATEs facilitate target-independent T-cell activation in tumors.
Malin Peter, Bettina Mundt, Arne Menze, Norman Woller, Valery Volk, Thomas C Wirth

EMBO Mol Med· February 2025

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Atezolizumab/bevacizumab and lenvatinib for hepatocellular carcinoma: A comparative analysis in a European real-world cohort.
Tiago de Castro, Sabrina Welland, Leonie Jochheim, Cathrine Leyh, Kateryna Shmanko, Thomas C Wirth

Hepatol Commun· November 2024

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Molecular diagnostics and therapies for gastrointestinal tumors: a real-world experience.
Sabrina Welland, Tiago deCastro, Melanie Bathon, Thomas Christian Wirth, Tanja Reineke-Plaaß

J Cancer Res Clin Oncol· August 2022

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Chemotherapy and Hepatic Steatosis: Impact on Postoperative Morbidity and Survival after Liver Resection for Colorectal Liver Metastases.
Jan C Mahlmann, Thomas C Wirth, Björn Hartleben, Harald Schrem, Jens F Mahlmann

Visc Med· June 2021

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Transcriptome Profiling Identifies TIGIT as a Marker of T-Cell Exhaustion in Liver Cancer.
Dmitrij Ostroumov, Steven Duong, Jessica Wingerath, Norman Woller, Michael P Manns, Thomas C Wirth

Hepatology· April 2021

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Of microspheres and microbes: A double-hit strategy for cancer immunotherapy.
Benjamin Brinkhoff, Thomas C Wirth

Oncoimmunology· February 2021

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Live vaccines-a short-cut to cancer viro-immunotherapy.
Thomas C Wirth, Julia Niemann, Florian Kühnel

EMBO Mol Med· January 2020

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Molecular retargeting of antibodies converts immune defense against oncolytic viruses into cancer immunotherapy.
Julia Niemann, Norman Woller, Jennifer Brooks, Bettina Fleischmann-Mundt, Nikolas T Martin, Thomas C Wirth

Nat Commun· July 2019

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Choledochal Cyst and Malignancy: A Plea for Lifelong Follow-Up.
Omid Madadi-Sanjani, Thomas C Wirth, Joachim F Kuebler, Claus Petersen, Benno M Ure

Eur J Pediatr Surg· April 2019

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HCC Immune Surveillance and Antiviral Therapy of Hepatitis C Virus Infection.
Solomon Owusu Sekyere, Bernhard Schlevogt, Friederike Mettke, Mohammad Kabbani, Katja Deterding, Thomas Christian Wirth

Liver Cancer· February 2019

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Associating Liver Partition and Portal vein ligation for Staged hepatectomy after pre-operative chemotherapy.
Florian W R Vondran, Felix Oldhafer, Kristina I Ringe, Thomas C Wirth, Moritz Kleine

ANZ J Surg· April 2018

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Perioperative, Spatiotemporally Coordinated Activation of T and NK Cells Prevents Recurrence of Pancreatic Cancer.
Jennifer Brooks, Bettina Fleischmann-Mundt, Norman Woller, Julia Niemann, Silvia Ribback, Thomas C Wirth

Cancer Res· January 2018

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Neoantigen Targeting-Dawn of a New Era in Cancer Immunotherapy?
Thomas C Wirth, Florian Kühnel

Front Immunol· December 2017

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Recombinant LCMV Vectors Induce Protective Immunity following Homologous and Heterologous Vaccinations.
Jessica Wingerath, Dmitrij Ostroumov, Norman Woller, Michael P Manns, Daniel D Pinschewer, Thomas C Wirth

Mol Ther· November 2017

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CD40 Signaling Drives Potent Cellular Immune Responses in Heterologous Cancer Vaccinations.
Supot Nimanong, Dmitrij Ostroumov, Jessica Wingerath, Sarah Knocke, Norman Woller, Thomas C Wirth

Cancer Res· April 2017

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Surveillance in cholangiocellular carcinoma.
Thomas C Wirth, Arndt Vogel

Best Pract Res Clin Gastroenterol· December 2016

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Tailored Tumor Immunogenicity Reveals Regulation of CD4 and CD8 T Cell Responses against Cancer.
Sarah Knocke, Bettina Fleischmann-Mundt, Michael Saborowski, Michael P Manns, Florian Kühnel, Thomas C Wirth

Cell Rep· November 2016

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Administration of Gemcitabine After Pancreatic Tumor Resection in Mice Induces an Antitumor Immune Response Mediated by Natural Killer Cells.
Engin Gürlevik, Bettina Fleischmann-Mundt, Jennifer Brooks, Ihsan Ekin Demir, Katja Steiger, Thomas C Wirth

Gastroenterology· August 2016

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Viral Infection of Tumors Overcomes Resistance to PD-1-immunotherapy by Broadening Neoantigenome-directed T-cell Responses.
Norman Woller, Engin Gürlevik, Bettina Fleischmann-Mundt, Anja Schumacher, Sarah Knocke, Thomas C Wirth

Mol Ther· October 2015

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Microsphere priming facilitates induction of potent therapeutic T-cell immune responses against autochthonous liver cancers.
Benjamin Brinkhoff, Dmitrij Ostroumov, Jessica Heemcke, Norman Woller, Engin Gürlevik, Thomas C Wirth

Eur J Immunol· April 2014

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Spontaneous and therapeutic immune responses in hepatocellular carcinoma: implications for current and future immunotherapies.
Thomas C Wirth

Expert Rev Gastroenterol Hepatol· January 2014

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