Publications by authors named "Thomas D Horvath"

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A Randomized Phase 1 Study Investigating Gut Microbiome Changes With Moxifloxacin vs Oral Vancomycin: Implications for Clostridioides difficile Risk.
Hossaena Ayele, Jinhee Jo, Khurshida Begum, Chenlin Hu, Thanh M Le, Thomas D Horvath

J Infect Dis· December 2025

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Heat-Induced Pathophysiological and Metabolic Changes at the Feto-Maternal Interface Predisposing to Preterm Birth.
Isidore Mushimiyimana, Lauren Richardson, Thomas D Horvath, Vladislav Orlovsky, Brinley Harrington

FASEB J· November 2025

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Identifying a therapeutic window of opportunity for people living with primary sclerosing cholangitis: Embryology and the overlap of inflammatory bowel disease with immune-mediated liver injury.
Richard Kellermayer, Marco Carbone, Thomas D Horvath, Reka G Szigeti, Cynthia Buness

Hepatology· October 2025

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Faecal pharmacokinetics, microbiome, and bile acid changes in healthy subjects given intravenous followed by oral omadacycline; a Phase 1 clinical trial.
Jinhee Jo, Travis J Carlson, Chenlin Hu, John C Williamson, Yolanda T Belin, Thomas D Horvath

J Antimicrob Chemother· October 2025

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The glutaminase activity of ASNS fuels glutamine metabolism in leukemia.
Wai-Kin Chan, Lin Tan, Sara A Martinez, Di Du, Thomas D Horvath

Haematologica· September 2025

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Efficacy, safety, pharmacokinetics, and associated microbiome changes of ibezapolstat compared with vancomycin in adults with Clostridioides difficile infection: a phase 2b, randomised, double-blind, active-controlled, multicentre study.
Taryn A Eubank, Jinhee Jo, M Jahangir Alam, Khurshida Begum, Jacob K McPherson, Thomas D Horvath

Lancet Microbe· August 2025

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Antibiofilm properties of 4-hydroxy-3-methyl-2-alkenylquinoline, a novel -derived alkaloid.
McKinley D Williams, Taylor R Sweeney, Sabrina Trieu, Ravi Orugunty, Abdelahhad Barbour, Thomas D Horvath

mSphere· May 2025

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colonization is not mediated by bile salts and utilizes Stickland fermentation of proline in an model.
Xiaoyun Huang, April E Johnson, Joshua N Brehm, Thi Van Thanh Do, Thomas A Auchtung, Thomas D Horvath

mSphere· February 2025

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Phase I trial comparing bile acid and short-chain fatty acid alterations in stool collected from human subjects treated with omadacycline or vancomycin.
Jinhee Jo, Chenlin Hu, Thomas D Horvath, Sigmund J Haidacher, Khurshida Begum

Antimicrob Agents Chemother· February 2025

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colonization is not mediated by bile salts and utilizes Stickland fermentation of proline in an model.
Xiaoyun Huang, April E Johnson, Joshua N Brehm, Thi Van Thanh Do, Thomas A Auchtung, Thomas D Horvath

bioRxiv· December 2024

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Phylogenetically diverse bacterial species produce histamine.
Kristen A Engevik, Amber Hazzard, Brenton Puckett, Kathleen M Hoch, Sigmund J Haidacher, Thomas D Horvath

Syst Appl Microbiol· September 2024

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Characterizing arginine, ornithine, and putrescine pathways in enteric pathobionts.
Ian M Lillie, Charles E Booth, Adelaide E Horvath, Matthew Mondragon, Melinda A Engevik, Thomas D Horvath

Microbiologyopen· April 2024

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Repurposing dried blood spot device technology to examine bile acid profiles in human dried fecal spot samples.
Melinda A Engevik, Santosh Thapa, Ian M Lillie, Mary Beth Yacyshyn, Bruce Yacyshyn, Thomas D Horvath

Am J Physiol Gastrointest Liver Physiol· February 2024

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Liquid Chromatography-Tandem Mass Spectrometry-Based Therapeutic Monitoring of Plasma Atovaquone Concentrations in Pediatric Patients.
Thomas D Horvath, Sridevi Devaraj

Methods Mol Biol· December 2023

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A high-throughput protocol for measuring solution pH of bacterial cultures using UV-Vis absorption spectrophotometry.
Kristen A Engevik, Hyland Gonzalez, Clay Daniels, Ronald K Stavert, Numan Oezguen, Thomas D Horvath

STAR Protoc· September 2023

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Discovery of phosphorylated lantibiotics with proimmune activity that regulate the oral microbiome.
Abdelahhad Barbour, Leif Smith, Morvarid Oveisi, McKinley Williams, Ruo Chen Huang, Thomas D Horvath

Proc Natl Acad Sci U S A· May 2023

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Interrogation of the mammalian gut-brain axis using LC-MS/MS-based targeted metabolomics with in vitro bacterial and organoid cultures and in vivo gnotobiotic mouse models.
Thomas D Horvath, Sigmund J Haidacher, Melinda A Engevik, Berkley Luck, Wenly Ruan

Nat Protoc· February 2023

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Addressing barriers in FAIR data practices for biomedical data.
Laura D Hughes, Ginger Tsueng, Jack DiGiovanna, Thomas D Horvath, Luke V Rasmussen

Sci Data· February 2023

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Serum 3-phenyllactic acid level is reduced in benign multiple sclerosis and is associated with effector B cell ratios.
Numan Oezguen, Vuslat Yılmaz, Thomas D Horvath, Ece Akbayir, Sigmund J Haidacher

Mult Scler Relat Disord· December 2022

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Validation of atovaquone plasma levels by liquid chromatography-tandem mass spectrometry for therapeutic drug monitoring in pediatric patients.
Thomas D Horvath, Izmarie Poventud-Fuentes, Lily Olayinka, Asha James, Sigmund J Haidacher

J Mass Spectrom Adv Clin Lab· November 2022

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Insights into Microbiome and Metabolic Signatures of Children Undergoing Peanut Oral Immunotherapy.
Andrea C Blackman, Santosh Thapa, Alamelu Venkatachalam, Thomas D Horvath, Jessica K Runge

Children (Basel)· August 2022

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colonization influences the abundance of intestinal short chain fatty acids and neurotransmitters.
Thomas D Horvath, Faith D Ihekweazu, Sigmund J Haidacher, Wenly Ruan, Kristen A Engevik

iScience· May 2022

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Mathematical models to study the biology of pathogens and the infectious diseases they cause.
Joao B Xavier, Jonathan M Monk, Saugat Poudel, Charles J Norsigian, Anand V Sastry, Thomas D Horvath

iScience· April 2022

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Unraveling the Metabolic Requirements of the Gut Commensal .
Robert Fultz, Taylor Ticer, Faith D Ihekweazu, Thomas D Horvath, Sigmund J Haidacher

Front Microbiol· November 2021

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Neurotransmitter Profiles Are Altered in the Gut and Brain of Mice Mono-Associated with .
Berkley Luck, Thomas D Horvath, Kristen A Engevik, Wenly Ruan, Sigmund J Haidacher

Biomolecules· July 2021

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