Publications by authors named "Thomas D Pfister"

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Safety, Immunologic, and Clinical Activity of Durvalumab in Combination with Olaparib or Cediranib in Advanced Leiomyosarcoma: Results of the DAPPER Clinical Trial.
Abdulazeez Salawu, Ben X Wang, Ming Han, Caryn Geady, Alya Heirali, Thomas D Pfister

Clin Cancer Res· October 2023

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Novel antibody reagents for characterization of drug- and tumor microenvironment-induced changes in epithelial-mesenchymal transition and cancer stem cells.
Tony Navas, Thomas D Pfister, Simona Colantonio, Amina Aziz, Lynda Dieckman

PLoS One· April 2019

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The root causes of pharmacodynamic assay failure.
Katherine V Ferry-Galow, Hala R Makhlouf, Deborah F Wilsker, Scott M Lawrence, Thomas D Pfister

Semin Oncol· August 2016

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Pharmacodynamic Response of the MET/HGF Receptor to Small-Molecule Tyrosine Kinase Inhibitors Examined with Validated, Fit-for-Clinic Immunoassays.
Apurva K Srivastava, Melinda G Hollingshead, Jennifer Weiner, Tony Navas, Yvonne A Evrard, Thomas D Pfister

Clin Cancer Res· July 2016

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Clinical and pharmacologic evaluation of two dosing schedules of indotecan (LMP400), a novel indenoisoquinoline, in patients with advanced solid tumors.
Shivaani Kummar, Alice Chen, Martin Gutierrez, Thomas D Pfister, Lihua Wang

Cancer Chemother Pharmacol· July 2016

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Enhancing Mn(II)-Binding and Manganese Peroxidase Activity in a Designed Cytochrome c Peroxidase through Fine-Tuning Secondary-Sphere Interactions.
Parisa Hosseinzadeh, Evan N Mirts, Thomas D Pfister, Yi-Gui Gao, Christopher Mayne

Biochemistry· March 2016

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Characterization of DNA topoisomerase I in three SN-38 resistant human colon cancer cell lines reveals a new pair of resistance-associated mutations.
Niels Frank Jensen, Keli Agama, Amit Roy, David Hersi Smith, Thomas D Pfister

J Exp Clin Cancer Res· March 2016

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ATR inhibitors VE-821 and VX-970 sensitize cancer cells to topoisomerase i inhibitors by disabling DNA replication initiation and fork elongation responses.
Rozenn Jossé, Scott E Martin, Rajarshi Guha, Pinar Ormanoglu, Thomas D Pfister

Cancer Res· December 2014

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Identifying the elusive sites of tyrosyl radicals in cytochrome c peroxidase: implications for oxidation of substrates bound at a site remote from the heme.
Kyle D Miner, Thomas D Pfister, Parisa Hosseinzadeh, Nadime Karaduman, Lynda J Donald

Biochemistry· June 2014

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Development and validation of an immunoassay for quantification of topoisomerase I in solid tumor tissues.
Thomas D Pfister, Melinda Hollingshead, Robert J Kinders, Yiping Zhang, Yvonne A Evrard

PLoS One· June 2013

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Exon array analyses across the NCI-60 reveal potential regulation of TOP1 by transcription pausing at guanosine quartets in the first intron.
William C Reinhold, Jean-Louis Mergny, Hongfang Liu, Michael Ryan, Thomas D Pfister

Cancer Res· March 2010

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Monitoring drug-induced gammaH2AX as a pharmacodynamic biomarker in individual circulating tumor cells.
Lihua H Wang, Thomas D Pfister, Ralph E Parchment, Shivaani Kummar, Larry Rubinstein

Clin Cancer Res· February 2010

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Topoisomerase I levels in the NCI-60 cancer cell line panel determined by validated ELISA and microarray analysis and correlation with indenoisoquinoline sensitivity.
Thomas D Pfister, William C Reinhold, Keli Agama, Shalu Gupta, Sonny A Khin

Mol Cancer Ther· July 2009

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Kinetic and crystallographic studies of a redesigned manganese-binding site in cytochrome c peroxidase.
Thomas D Pfister, Amir Y Mirarefi, Alan J Gengenbach, Xuan Zhao, Connor Danstrom

J Biol Inorg Chem· January 2007

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Responses of protein phosphatases and cAMP-dependent protein kinase in a freeze-avoiding insect, Epiblema scudderiana.
Thomas D Pfister, Kenneth B Storey

Arch Insect Biochem Physiol· May 2006

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Insect freeze tolerance: Roles of protein phosphatases and protein kinase A.
Thomas D Pfister, Kenneth B Storey

Insect Biochem Mol Biol· January 2006

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Monooxygenation of an aromatic ring by F43W/H64D/V68I myoglobin mutant and hydrogen peroxide. Myoglobin mutants as a model for P450 hydroxylation chemistry.
Thomas D Pfister, Takahiro Ohki, Takafumi Ueno, Isao Hara, Seiji Adachi

J Biol Chem· April 2005

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Hopping in the electron-transfer photocycle of the 1:1 complex of Zn-cytochrome c peroxidase with cytochrome c.
Jennifer L Seifert, Thomas D Pfister, Judith M Nocek, Yi Lu, Brian M Hoffman

J Am Chem Soc· April 2005

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A site-selective dual anchoring strategy for artificial metalloprotein design.
James R Carey, Steven K Ma, Thomas D Pfister, Dewain K Garner, Hyeon K Kim

J Am Chem Soc· September 2004

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Resonance Raman spectroscopy of cytochrome c peroxidase variants that mimic manganese peroxidase.
Manliang Feng, Hiroyasu Tachikawa, Xiaotang Wang, Thomas D Pfister, Alan J Gengenbach

J Biol Inorg Chem· September 2003

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Neutral thiol as a proximal ligand to ferrous heme iron: implications for heme proteins that lose cysteine thiolate ligation on reduction.
Roshan Perera, Masanori Sono, Jeffrey A Sigman, Thomas D Pfister, Yi Lu

Proc Natl Acad Sci U S A· April 2003

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Purification and characterization of protein phosphatase-1 from two cold-hardy goldenrod gall insects.
Thomas D Pfister, Kenneth B Storey

Arch Insect Biochem Physiol· January 2002

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