Publications by authors named "Thomas Ekstrom"

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Transcriptional pause release at enhancers mediates cell identity.
Thomas L Ekstrom, Steven A Johnsen

NAR Cancer· December 2025

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Glucocorticoid receptor suppresses GATA6-mediated RNA polymerase II pause release to modulate classical subtype identity in pancreatic cancer.
Thomas L Ekstrom, Raya M Rosok, Amro M Abdelrahman, Christina Parassiadis, Meghana Manjunath

Gut· June 2025

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USP44 Overexpression Drives a MYC-Like Gene Expression Program in Neuroblastoma through Epigenetic Reprogramming.
Thomas L Ekstrom, Sajjad Hussain, Tibor Bedekovics, Asma Ali, Lucia Paolini

Mol Cancer Res· September 2024

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Interactive enhancer hubs (iHUBs) mediate transcriptional reprogramming and adaptive resistance in pancreatic cancer.
Feda H Hamdan, Amro M Abdelrahman, Ana Patricia Kutschat, Xin Wang, Thomas L Ekstrom

Gut· June 2023

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Repurposing Ceritinib Induces DNA Damage and Enhances PARP Inhibitor Responses in High-Grade Serous Ovarian Carcinoma.
Arun Kanakkanthara, Xiaonan Hou, Thomas L Ekstrom, Valentina Zanfagnin, Amelia M Huehls

Cancer Res· January 2022

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Aiming for the Bullseye: Targeted activities decrease misconceptions related to enzyme function for undergraduate biochemistry students.
Cassidy R Terrell, Thomas Ekstrom, Brian Nguyen, Kyle Nickodem

Biochem Mol Biol Educ· November 2021

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VLX600 Disrupts Homologous Recombination and Synergizes with PARP Inhibitors and Cisplatin by Inhibiting Histone Lysine Demethylases.
Thomas L Ekstrom, Nicholas M Pathoulas, Amelia M Huehls, Arun Kanakkanthara, Larry M Karnitz

Mol Cancer Ther· September 2021

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BRCA1 Deficiency Upregulates NNMT, Which Reprograms Metabolism and Sensitizes Ovarian Cancer Cells to Mitochondrial Metabolic Targeting Agents.
Arun Kanakkanthara, Kiran Kurmi, Thomas L Ekstrom, Xiaonan Hou, Emma R Purfeerst

Cancer Res· December 2019

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Robust activation of microhomology-mediated end joining for precision gene editing applications.
Hirotaka Ata, Thomas L Ekstrom, Gabriel Martínez-Gálvez, Carla M Mann, Alexey V Dvornikov

PLoS Genet· September 2018

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