Publications by authors named "Thomas Eling"

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NAG-1/GDF15 as a tumor suppressor in colorectal cancer: inhibition of β-catenin and NF-κB pathways via interaction with EpCAM.
Jaehak Lee, Ilju Kim, Junsun Ryu, Thomas Eling, Seung Joon Baek

Cell Death Dis· May 2025

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NAG-1/GDF15 inhibits diabetic nephropathy via inhibiting AGE/RAGE-mediated inflammation signaling pathways in C57BL/6 mice and HK-2 cells.
Jiajun Chen, He Peng, Chaojie Chen, Ying Wang, Tingting Sang, Thomas Eling

Life Sci· December 2022

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NAG-1/GDF15 protects against streptozotocin-induced type 1 diabetes by inhibiting apoptosis, preserving beta-cell function, and suppressing inflammation in pancreatic islets.
Ying Wang, Jiajun Chen, Tingting Sang, Chaojie Chen, He Peng, Thomas Eling

Mol Cell Endocrinol· June 2022

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Overexpression of NAG-1/GDF15 prevents hepatic steatosis through inhibiting oxidative stress-mediated dsDNA release and AIM2 inflammasome activation.
Ying Wang, Chaojie Chen, Jiajun Chen, Tingting Sang, He Peng, Thomas Eling

Redox Biol· June 2022

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The anti-diabetic effects of NAG-1/GDF15 on HFD/STZ-induced mice.
Pattawika Lertpatipanpong, Jaehak Lee, Ilju Kim, Thomas Eling, Seung Yeon Oh

Sci Rep· July 2021

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Activation of TRPA1 by volatile organic chemicals leading to sensory irritation.
Jeanelle M Martinez, Thomas E Eling

ALTEX· May 2020

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Growth differentiation factor 15 (GDF15): A survival protein with therapeutic potential in metabolic diseases.
Seung Joon Baek, Thomas Eling

Pharmacol Ther· June 2019

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Overproduction of growth differentiation factor 15 promotes human rhinovirus infection and virus-induced inflammation in the lung.
Qun Wu, Di Jiang, Niccolette R Schaefer, Laura Harmacek, Brian P O'Connor, Thomas E Eling

Am J Physiol Lung Cell Mol Physiol· March 2018

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Expression of Human NSAID Activated Gene 1 in Mice Leads to Altered Mammary Gland Differentiation and Impaired Lactation.
April K Binder, Justin P Kosak, Kyathanahalli S Janardhan, Glenda Moser, Thomas E Eling

PLoS One· July 2016

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Correction: Expression of Human NSAID Activated Gene 1 in Mice Leads to Altered Mammary Gland Differentiation and Impaired Lactation.
April K Binder, Justin P Kosak, Kyathanahalli S Janardhan, Glenda Moser, Thomas E Eling

PLoS One· July 2016

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Reinterpreting the best biomarker of oxidative stress: The 8-iso-prostaglandin F2α/prostaglandin F2α ratio shows complex origins of lipid peroxidation biomarkers in animal models.
Thomas J Van't Erve, Fred B Lih, Casey Jelsema, Leesa J Deterding, Thomas E Eling

Free Radic Biol Med· June 2016

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Reinterpreting the best biomarker of oxidative stress: The 8-iso-PGF(2α)/PGF(2α) ratio distinguishes chemical from enzymatic lipid peroxidation.
Thomas J van 't Erve, Fred B Lih, Maria B Kadiiska, Leesa J Deterding, Thomas E Eling

Free Radic Biol Med· June 2015

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hNAG-1 increases lifespan by regulating energy metabolism and insulin/IGF-1/mTOR signaling.
Xingya Wang, Kali Chrysovergis, Justin Kosak, Grace Kissling, Mike Streicker, Thomas E Eling

Aging (Albany NY)· August 2014

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Lower NLRP3 inflammasome activity in NAG-1 transgenic mice is linked to a resistance to obesity and increased insulin sensitivity.
Xingya Wang, Kali Chrysovergis, Justin Kosak, Thomas E Eling

Obesity (Silver Spring)· May 2014

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Anti-tumor activity of non-steroidal anti-inflammatory drugs: cyclooxygenase-independent targets.
Jason L Liggett, Xiaobo Zhang, Thomas E Eling, Seung Joon Baek

Cancer Lett· May 2014

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Obesity, rather than diet, drives epigenomic alterations in colonic epithelium resembling cancer progression.
Ruifang Li, Sara A Grimm, Kaliopi Chrysovergis, Justin Kosak, Xingya Wang, Thomas E Eling

Cell Metab· April 2014

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The diverse roles of nonsteroidal anti-inflammatory drug activated gene (NAG-1/GDF15) in cancer.
Xingya Wang, Seung Joon Baek, Thomas E Eling

Biochem Pharmacol· March 2013

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Proteasome inhibitor MG132 induces NAG-1/GDF15 expression through the p38 MAPK pathway in glioblastoma cells.
Sachie Shimizu, Mitsutoshi Kadowaki, Hiroki Yoshioka, Atsushi Kambe, Takashi Watanabe, Thomas E Eling

Biochem Biophys Res Commun· January 2013

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The H6D variant of NAG-1/GDF15 inhibits prostate xenograft growth in vivo.
Xingya Wang, Kali Chrysovergis, Rachelle J Bienstock, Minsub Shim, Thomas E Eling

Prostate· May 2012

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DNA methylation-mediated silencing of nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) in glioma cell lines.
Mitsutoshi Kadowaki, Hiroki Yoshioka, Hideki Kamitani, Takashi Watanabe, Paul A Wade, Thomas E Eling

Int J Cancer· January 2012

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COX inhibitors directly alter gene expression: role in cancer prevention?
Xingya Wang, Seung Joon Baek, Thomas Eling

Cancer Metastasis Rev· December 2011

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Resveratrol-induced apoptosis is mediated by early growth response-1, Krüppel-like factor 4, and activating transcription factor 3.
Nichelle C Whitlock, Jae Hoon Bahn, Seong-Ho Lee, Thomas E Eling, Seung Joon Baek

Cancer Prev Res (Phila)· January 2011

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The role of NAG-1/GDF15 in the inhibition of intestinal polyps in APC/Min mice by sulindac.
Xingya Wang, Philip J Kingsley, Larry J Marnett, Thomas E Eling

Cancer Prev Res (Phila)· January 2011

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Embryonic expression of cyclooxygenase-2 causes malformations in axial skeleton.
Minsub Shim, Julie Foley, Colleen Anna, Yuji Mishina, Thomas Eling

J Biol Chem· May 2010

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The cyclooxygenase inhibitor sulindac sulfide inhibits EP4 expression and suppresses the growth of glioblastoma cells.
Atsushi Kambe, Hiroki Yoshioka, Hideki Kamitani, Takashi Watanabe, Seung Joon Baek, Thomas E Eling

Cancer Prev Res (Phila)· December 2009

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