Publications by authors named "Thomas Flad"

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Host cell protein detection gap risk mitigation: quantitative IAC-MS for ELISA antibody reagent coverage determination.
Daniel M Waldera-Lupa, Yvonne Jasper, Pia Köhne, Ronja Schwichtenhövel, Heiner Falkenberg, Thomas Flad

MAbs· January 2022

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Mass spectrometric evaluation of upstream and downstream process influences on host cell protein patterns in biopharmaceutical products.
Heiner Falkenberg, Daniel Michael Waldera-Lupa, Martin Vanderlaan, Thomas Schwab, Kurt Krapfenbauer, Thomas Flad

Biotechnol Prog· May 2019

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Haptoglobin-α1, -α2, vitamin D-binding protein and apolipoprotein C-III as predictors of etanercept drug response in rheumatoid arthritis.
Sabine Blaschke, Kathinka Rinke, Michael Maring, Thomas Flad, Susann Patschan

Arthritis Res Ther· March 2015

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Development of a fluorescence resonance energy transfer peptide library technology for detection of protease contaminants in protein-based raw materials used in diagnostic assays.
Hans-Peter Kapprell, Andreas Maurer, Florian Kramer, Boris Heinrich, Carsten Buenning, Thomas Flad

Assay Drug Dev Technol· October 2011

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Identification of serum proteins involved in pancreatic cancer cachexia.
Klaus Felix, Frederik Fakelman, Daniel Hartmann, Nathalia A Giese, Matthias M Gaida, Thomas Flad

Life Sci· January 2011

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Immuno-MALDI-TOF MS: new perspectives for clinical applications of mass spectrometry.
Katrin Sparbier, Thomas Wenzel, Hassan Dihazi, Sabine Blaschke, Gerhard-Anton Müller, Thomas Flad

Proteomics· March 2009

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Neural cell adhesion molecule expression on renal interstitial cells.
Jasmina Marković-Lipkovski, Claudia A Müller, Gerd Klein, Thomas Flad, Tatjana Klatt

Nephrol Dial Transplant· June 2007

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Whole cell profiling and identification of galectin-1 as a potential marker of renal cell carcinoma.
Hassan Dihazi, Claudia Müller, Abdul R Asif, Thomas Flad, Abderrahim Elmaouhoub

Proteomics Clin Appl· February 2007

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Direct protein identification from nonspecific peptide pools by high-accuracy MS data filtering.
Vinh An Thieu, Dieter Kirsch, Thomas Flad, Claudia Müller, Bernhard Spengler

Angew Chem Int Ed Engl· May 2006

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Cathepsin D is present in human eccrine sweat and involved in the postsecretory processing of the antimicrobial peptide DCD-1L.
Daniel Baechle, Thomas Flad, Alexander Cansier, Heiko Steffen, Birgit Schittek

J Biol Chem· March 2006

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T cell epitope definition by differential mass spectrometry: identification of a novel, immunogenic HLA-B8 ligand directly from renal cancer tissue.
Thomas Flad, Ludmila Mueller, Hassan Dihazi, Veneta Grigorova, Ralf Bogumil

Proteomics· January 2006

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Differential detection of S100A8 in transitional cell carcinoma of the bladder by pair wise tissue proteomic and immunohistochemical analysis.
Jonathan P Tolson, Thomas Flad, Volker Gnau, Hassan Dihazi, Joerg Hennenlotter

Proteomics· January 2006

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Expansion of peripheral CD8+ CD28- T cells in response to Epstein-Barr virus in patients with rheumatoid arthritis.
Tatjana Klatt, Qin Ouyang, Thomas Flad, Ina Koetter, Hans-Jörg Bühring

J Rheumatol· February 2005

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Mass spectrometry meets medical sciences: making headway in molecular disease diagnostics.
Thomas Flad, Jonathan Tolson

Anal Bioanal Chem· January 2005

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Serum protein profiling by SELDI mass spectrometry: detection of multiple variants of serum amyloid alpha in renal cancer patients.
Jonathan Tolson, Ralf Bogumil, Elke Brunst, Hermann Beck, Raimund Elsner, Thomas Flad

Lab Invest· July 2004

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Development of an MHC-class I peptide selection assay combining nanoparticle technology and matrix-assisted laser desorption/ionisation mass spectrometry.
Thomas Flad, Thomas Schiestel, Herwig Brunner, Jonathan Tolson, Qin Ouyang

J Immunol Methods· December 2003

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Detection of dermcidin-derived peptides in sweat by ProteinChip technology.
Thomas Flad, Ralf Bogumil, Jonathan Tolson, Birgit Schittek, Claus Garbe

J Immunol Methods· December 2002

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Cathepsin S activity is detectable in human keratinocytes and is selectively upregulated upon stimulation with interferon-gamma.
Gerold Schwarz, Wolf-Henning Boehncke, Manuela Braun, Christian J Schröter, Timo Burster, Thomas Flad

J Invest Dermatol· July 2002

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Human alpha-defensins HNPs-1, -2, and -3 in renal cell carcinoma: influences on tumor cell proliferation.
Claudia A Müller, Jasmina Markovic-Lipkovski, Tatjana Klatt, Jutta Gamper, Gerold Schwarz, Thomas Flad

Am J Pathol· April 2002

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